Table 6Definitions of the grades of the overall strength of evidence

GradeDefinition
HighFurther research is very unlikely to change our confidence in the estimate of effect.
ModerateFurther research is likely to have an important impact on our confidence in the estimate of the effect and may change the estimate.
LowFurther research is very likely to have an important impact on our confidence in the estimate of the effect and is likely to change the estimate.

Source: Adapted from the GRADE working group.18

From: Methods

Cover of Drug Class Review: Constipation Drugs
Drug Class Review: Constipation Drugs: Final Report [Internet].
Gartlehner G, Jonas DE, Morgan LC, et al.
Portland (OR): Oregon Health & Science University; 2007 Sep.
Copyright © 2007, Oregon Health & Science University, Portland, Oregon.

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