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Treadwell J, Tipton K, Oyesanmi O, et al. Surgical Options for Inguinal Hernia: Comparative Effectiveness Review [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2012 Aug. (Comparative Effectiveness Reviews, No. 70.)

Cover of Surgical Options for Inguinal Hernia: Comparative Effectiveness Review

Surgical Options for Inguinal Hernia: Comparative Effectiveness Review [Internet].

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Appendix ASearch Strategy

Electronic Database Searches

The following databases have been searched for relevant information:

NameDate LimitsPlatform/Provider
ClinicalTrials​.govSearched October 29, 2010www​.clinicaltrials.gov
The Cochrane Central Register of Controlled Trials (CENTRAL)Through 2010, Issue 10www​.thecochranelibrary.com
The Cochrane Database of Methodology Reviews (Methodology Reviews)Through 2010, Issue 10www​.thecochranelibrary.com
The Cochrane Database of Systematic Reviews (Cochrane Reviews)Through 2010, Issue 10www​.thecochranelibrary.com
Database of Abstracts of Reviews of Effects (DARE)Through 2010, Issue 10www​.thecochranelibrary.com
EMBASE (Excerpta Medica)1990 through November 4, 2011OVID SP
Health Technology Assessment Database (HTA)Through 2010, Issue 10www​.thecochranelibrary.com
MEDLINE and PreMEDLINE1999 through November 4, 2011OVID SP
PubMedSearched November 17, 2011http://www​.ncbi.nlm.nih.gov/pubmed
U.K. National Health Service Economic Evaluation Database (NHS EED)Through 2010, Issue 10www​.thecochranelibrary.com

Hand Searches of Journal and Nonjournal Literature

Journals and supplements maintained in ECRI Institute's collections were routinely reviewed. Nonjournal publications and conference proceedings from professional organizations, private agencies, and government agencies were also screened. Other mechanisms used to retrieve additional relevant information included review of bibliographies/reference lists from peer-reviewed and gray literature. (Gray literature consists of reports, studies, articles, and monographs produced by federal and local government agencies, private organizations, educational facilities, consulting firms, and corporations. These documents do not appear in the peer-reviewed journal literature.)

The search strategies employed combinations of freetext keywords as well as controlled vocabulary terms including (but not limited to) the following concepts. The strategy below is presented in OVID syntax; the search was simultaneously conducted across EMBASE and MEDLINE. A parallel strategy was used to search the databases comprising the Cochrane Library.

Medical Subject Headings (MeSH), EMTREE, PsycINFO and Keywords

Conventions:

OVID

$=truncation character (wildcard)
exp=“explodes” controlled vocabulary term (e.g., expands search to all more specific related terms in the vocabulary's hierarchy)
.de. or /=limit controlled vocabulary heading
.fs.=floating subheading
.hw=limit to heading word
.md.=type of methodology (PsycINFO)
.mp.=combined search fields (default if no fields are specified)
.pt.=publication type
.ti.=limit to title
.tw.=limit to title and abstract fields

PubMed

[mh]=MeSH heading
[majr]=MeSH heading designated as major topic
[pt]=publication type
[sb]=subset of PubMed database (In Process, Publisher, Systematic)
[sh]=MeSH subheading (qualifiers used in conjunction with MeSH headings)
[tiab]=keyword in title or abstract

Topic-Specific Search Terms – Alphabetical Listing

ConceptControlled VocabularyKeywords
Adverse effectsLaparoscopy/ae
Patient safety/
Adverse effect$
Adverse event$
Bowel
Bladder
Complication$
Injur$
Numbness
Patient and safety
Recurrence
Vascular
Visceral
CostsCost-benefit analysis/
Cost and cost analysis/
Cost effectiveness analysis/
Laparoscopy/economics
Cost$
Cost benefit analysis
Cost?effectiveness
HerniaHernia, inguinal/
Inguinal canal
Inguinal hernia/
Inguinal region/
Abdominal
Direct
Fascia
Groin
Hernia
Hernias
Indirect
Inguinal
Surgical deviceFibrin glue/ad
Laparoscope/
Polypropylenes/
Surgical equipment/
Surgical mesh
Bassini
Composix
Fibrin glue
Hernia
Implant$
Intra?peritoneal onlay mesh
IPOM
Kugel
McVay
Mesh
Mesh plug
Polypropylene
Prolene
PTFE
Shouldice
Stoppa
Suture
Synthetic mesh
Total extra?peritoneal
Transabdominal pre?peritoneal
Ugahary
Surgical experienceInguinal hernia/su
Laparoscopic surgery/me
Surgery/me
Education
Experience
Expert$
Knowledge
Learning curve
Training
Volume adj outcome$
Surgical techniqueExp surgical approach/
Exp surgical equipment/
Exp surgical technique/
Hernioplasty/
Herniorrhaphy/
Laparoscopy/me
Laparoscopic surgery/
Su.fs.
Extra adj peritoneal
Intra adj peritoneal
Hernioplast$
Herniorrhaph$
Intraperitoneal onlay mesh
IPOM
Laparoscop$
Lichtenstein
Mesh plug
Minimal access laparoscop$
Minimally invasive
Open mesh
Open and surg$
Preperitoneal
TAPP
TEP
Total extraperitoneal
Transabdominal
Transperitoneal
Treatment outcomeClinical effectiveness/
Convalescence/
Length of stay/
Operation duration/
Pain, postoperative/
Pain measurement/
Postoperative complications/
Postoperative pain/
Recurrence/pc
Treatment outcome/
Heal$
Outcome$
Pain
Painful

EMBASE/MEDLINE

Remove overlap, 1990-current

Set NumberConceptSearch Statement
1HerniaHernia, inguinal/ or inguinal hernia/ or inguinal canal/ or inguinal region/
2((hernia or hernias) and (groin or inguinal or direct or indirect or fascia or abdominal)).ti,ab.
3Combine setsor/1-2
4Surgical techniqueLaparoscopy/me or laparoscopic surgery/ or hernioplasty/ or herniorrhaphy/
5Exp surgical approach/ or exp surgical technique/ or exp surgical equipment/ or su.fs.
6(Lichtenstein or open mesh or laparscop$ or extra?peritoneal or intra?peritoneal or pre?peritoneal or hernioplast$ or herniorrhaph$ or (minimal adj (access or invasive)) or transabdominal or transperitoneal or mesh plug).mp. or ((open and surg$) or (extra adj peritoneal) or (intra adj peritoneal)).ti,ab.
7Combine setsor/4-6
8Surgical experienceLaparoscopic surgery/ or inguinal hernia/su or surgery/me or laparoscopy/
9(educat$ or train$ or knowledge or experience or expert$ or learning curve or (volume adj2 outcome$)).mp.
10Combine sets8 and 9
11Surgical deviceSurgical mesh/ or polypropylene/ or surgical equipment/ or laparoscope/ or fibrin glue/ad
12(mesh or plug or polypropylene or prolene or synthetic or PTFE or prosthesis or prostheses or fibrin glue or suture$ or implant$).mp.
13(Prolene hernia system or mesh plug or composix or kugel or bassini or shouldice or Lichtenstein or mcvay or stoppa or ugahary or “transabdominal pre?peritoneal” or “TAPP” or “TEP” or total extra?peritoneal or “IPOM” or “intra?peritoneal onlay mesh”).mp.
14Combine setsor/11-13
15Treatment outcomePain, postoperative/ or pain measurement/ or postoperative complications/ or recurrence/pc or treatment outcome/ or convalescence/ or length of stay/ or operation duration/ or (pain and (adverse events or complications)).fs.
16(pain or painful or outcome$ or heal$).mp.
17Adverse effectsLaparoscopy/ae or patient safety or ((injur$ and (vascular or visceral or bladder or bowel)) or adverse effect$ or adverse event$ or complication$ or (patient and safety) or recurrence or numbness).mp.
18Treatment outcome/ or clinical effectiveness
19Combine setsor/15-18
20CostCost analysis/ or cost-benefit analysis/ or laparoscopy/ec or cost effectiveness analysis/ or cost benefit analysis.mp. or cost$.mp. or cost?effective$.mp.
21Combine sets: Hernia, surgical technique or device3 and (7 or 14)
22Combine sets: Hernia and surgical experience3 and 10
23Combine sets: Surgical experience and costs, outcomes, adverse effects22 and (19 or 20)
24Combine sets: Hernia, surgical technique, device, costs, outcomes, adverse effects21 and (19 or 20)
25Combine sets:23 or 24
26Limit by dateLimit 25 to yr=“1990-2011”
27Eliminate overlapRemove duplicates from 25
28Eliminate pub types27 not (letter/ or editorial/ or news/ or comment/ or case report.mp. or case reports/ or note/ or conference paper/ or (letter or editorial or news or comment or case reports).pt.)
29Apply trials hedge28 and (Randomized controlled trial/ or random allocation/ or double-blind method/ or single-blind method/ or placebos/ or cross-over studies/ or crossover procedure/ or cross over studies/ or double blind procedure/ or single blind procedure/ or placebo/ or latin square design/ or crossover design/ or double-blind studies/ or single-blind studies/ or tripleblind studies/ or random assignment/ or exp controlled study/ or exp clinical trial/ or exp comparative study/ or cohort analysis.mp. or follow-up studies/ or intermethod comparison/ or parallel design/ or control group/ or prospective study/ or retrospective study/ or case control study/ or major clinical study/ or evaluation studies/ or follow-up studies/ or random$.hw. or random$.ti. or placebo$.mp. or ((singl$ or doubl$ or tripl$ or trebl$) and (dummy or blind or sham)).mp. or latin square.mp. or ISRCTN$.mp. or ACTRN$.mp. or (NCT$ not NCT).mp.)
30Apply systematic review hedge28 and ((research synthesis or pooled).mp. or systematic review/ or meta analysis/ or metaanalysis/ or ((evidence base$ or methodol$ or systematic or quantitative$ or studies or search$).mp. and (review/ or review.pt.)))
31Combine29 or 30
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