BOX 1-1Particular Issues Surrounding Animal Use in Neuroscience

  • Models of nervous system disease may include behavioral and cognitive phenotypes that have the potential to result in suffering:
    • Research on conditions such as addiction, depression, anxiety, and fear may be problematic.
  • Pain, which is normally avoided in the design of experiments, is an important topic of study.
  • Modification of sensory experience may be considered a form of suffering.
  • Non-human primate use raises concerns due to costs and public perception.
  • Research may involve invasive methodology, restriction or control of food or water intake, and/or prolonged or repetitive procedures.

SOURCE: Blakemore presentation.

From: 1, Introduction and Overview

Cover of International Animal Research Regulations
International Animal Research Regulations: Impact on Neuroscience Research: Workshop Summary.
Institute of Medicine (US); National Research Council (US).
Washington (DC): National Academies Press (US); 2012.
Copyright © 2012, National Academy of Sciences.

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