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Results: 1 to 20 of 114

1.

RHO GTPases Activate Formins

Formins are a family of proteins with 15 members in mammals, organized into 8 subfamilies. Formins are involved in the regulation of actin cytoskeleton. Many but not all formin family members are activated by RHO GTPases. Formins that serve as effectors of RHO GTPases belong to different...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
2.

RHO GTPase Effectors

RHO GTPases regulate cell behaviour by activating a number of downstream effectors that regulate cytoskeletal organization, intracellular trafficking and transcription (reviewed by Sahai and Marshall 2002).One of the best studied RHO GTPase effectors are protein kinases ROCK1 and...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
3.

mitotic cell cycle phase

One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1129320
GO
: GO:0098763
4.

CENP-A containing chromatin organization

Any process that results in the specification, formation or maintenance of the physical structure of CENP-A containing chromatin. Synonym: centromeric chromatin organization;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1039895
GO
: GO:0061641
5.

biological phase

A distinct period or stage in a biological process or cycle.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1022085
GO
: GO:0044848
6.

chromosomal region

Any subdivision of a chromosome along its length. Synonym: chromosome region;

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
994751
GO
: GO:0098687
7.

organic cyclic compound metabolic process

The chemical reactions and pathways involving organic cyclic compound. Synonym: organic cyclic compound metabolism;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
754322
GO
: GO:1901360
8.

single-organism cellular process

Any process that is carried out at the cellular level, occurring within a single organism.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
751905
GO
: GO:0044763
9.

single organism signaling

A signaling process occurring within a single organism.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
751844
GO
: GO:0044700
10.

single-organism process

A biological process that involves only one organism. Synonym: single organism process;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
751843
GO
: GO:0044699
11.

Separation of Sister Chromatids

While sister chromatids resolve in prometaphase, separating along chromosomal arms, the cohesion of sister centromeres persists until anaphase. At the anaphase onset, the anaphase promoting complex/cyclosome (APC/C) ubiquitinates PTTG1 (securin), targeting it for degradation (Hagting...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
12.

Mitotic Metaphase and Anaphase

Metaphase is marked by the formation of the metaphase plate. The metaphase plate is formed when the spindle fibers align the chromosomes along the middle of the cell. Such an organization helps to ensure that later, when the chromosomes are separated, each new nucleus that is formed...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
13.

Resolution of Sister Chromatid Cohesion

The resolution of sister chromatids in mitotic prometaphase involves removal of cohesin complexes from chromosomal arms, with preservation of cohesion at centromeres (Losada et al. 1998, Hauf et al. 2001, Hauf et al. 2005). CDK1-mediated phosphorylation of cohesin-bound CDCA5 (Sororin)...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
14.

Cell Cycle

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
15.

nucleic acid metabolic process

Any cellular metabolic process involving nucleic acids.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
518444
GO
: GO:0090304
16.

cellular component organization or biogenesis

A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. Synonyms: GO:0071841; cellular component organisation or biogenesis; cellular component organisation or biogenesis at cellular...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
516762
GO
: GO:0071840
17.

protein-DNA complex subunit organization

Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex. Synonyms: DNA-protein complex subunit organization; protein-DNA complex subunit organisation;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
516746
GO
: GO:0071824
18.

protein complex subunit organization

Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex. Synonym: protein complex subunit organisation;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
516744
GO
: GO:0071822
19.

organic substance metabolic process

The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. Synonyms: organic molecular entity metabolic process; organic molecular entity metabolism; organic substance metabolism;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
516628
GO
: GO:0071704
20.

DNA conformation change

A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule. Synonym: DNA conformation modification;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
516029
GO
: GO:0071103

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