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Results: 1 to 20 of 409

1.

AMPK signaling pathway

AMP-activated protein kinase (AMPK) is a serine threonine kinase that is highly conserved through evolution. AMPK system acts as a sensor of cellular energy status. It is activated by increases in the cellular AMP:ATP ratio caused by metabolic stresses that either interfere with ATP...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
2.

AMPK signaling pathway

AMP-activated protein kinase (AMPK) is a serine threonine kinase that is highly conserved through evolution. AMPK system acts as a sensor of cellular energy status. It is activated by increases in the cellular AMP:ATP ratio caused by metabolic stresses that either interfere with ATP...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
3.

cGMP-PKG signaling pathway

Cyclic GMP (cGMP) is the intracellular second messenger that mediates the action of nitric oxide (NO) and natriuretic peptides (NPs), regulating a broad array of physiologic processes. The elevated intracellular cGMP level exerts its physiological action through two forms of cGMP-dependent...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
4.

cGMP-PKG signaling pathway

Cyclic GMP (cGMP) is the intracellular second messenger that mediates the action of nitric oxide (NO) and natriuretic peptides (NPs), regulating a broad array of physiologic processes. The elevated intracellular cGMP level exerts its physiological action through two forms of cGMP-dependent...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
5.

protein kinase complex

A protein complex which is capable of protein kinase activity.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
982479
GO
: GO:1902911
6.

membrane region

A membrane that is a part of a larger membrane. Examples include the apical region of the plasma membrane of an epithelial cell and the various regions of the endoplasmic reticulum membrane. Synonym: region of membrane;

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
948871
GO
: GO:0098589
7.

bounding membrane of organelle

The lipid bilayer that forms the outer-most layer of an organelle.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
948870
GO
: GO:0098588
8.

FoxO signaling pathway

The forkhead box O (FOXO) family of transcription factors regulates the expression of genes in cellular physiological events including apoptosis, cell-cycle control, glucose metabolism, oxidative stress resistance, and longevity. A central regulatory mechanism of FOXO proteins is...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
9.

positive regulation of intracellular signal transduction

Any process that activates or increases the frequency, rate or extent of intracellular signal transduction. Synonyms: GO:0010740; activation of intracellular signal transduction; activation of intracellular signal transduction pathway; activation of intracellular signaling cascade;...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
921132
GO
: GO:1902533
10.

regulation of intracellular signal transduction

Any process that modulates the frequency, rate or extent of intracellular signal transduction. Synonyms: GO:0010627; regulation of intracellular protein kinase cascade; regulation of intracellular signal transduction pathway; regulation of intracellular signaling cascade; regulation...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
921130
GO
: GO:1902531
11.

transferase complex

A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor).

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
911534
GO
: GO:1990234
12.

catalytic complex

A protein complex which is capable of catalytic activity. Synonym: enzyme complex;

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
911482
GO
: GO:1902494
13.

Rap1 signaling pathway

Rap1 is a small GTPase that controls diverse processes, such as cell adhesion, cell-cell junction formation and cell polarity. Like all G proteins, Rap1 cycles between an inactive GDP-bound and an active GTP-bound conformation. A variety of extracellular signals control this cycle...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
14.

Rap1 signaling pathway

Rap1 is a small GTPase that controls diverse processes, such as cell adhesion, cell-cell junction formation and cell polarity. Like all G proteins, Rap1 cycles between an inactive GDP-bound and an active GTP-bound conformation. A variety of extracellular signals control this cycle...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
15.

Ras signaling pathway

The Ras proteins are GTPases that function as molecular switches for signaling pathways regulating cell proliferation, survival, growth, migration, differentiation or cytoskeletal dynamism. Ras proteins transduce signals from extracellular growth factors by cycling between inactive...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
16.

Non-alcoholic fatty liver disease (NAFLD)

Non-alcoholic fatty liver disease (NAFLD) represents a spectrum ranging from simple steatosis to more severe steatohepatitis with hepatic inflammation and fibrosis, known as nonalcoholic steatohepatitis (NASH). NASH may further lead to cirrhosis and hepatocellular carcinoma (HCC)....

Type
:
pathway
Taxonomic scope
:
conserved biosystem
17.

Non-alcoholic fatty liver disease (NAFLD)

Non-alcoholic fatty liver disease (NAFLD) represents a spectrum ranging from simple steatosis to more severe steatohepatitis with hepatic inflammation and fibrosis, known as nonalcoholic steatohepatitis (NASH). NASH may further lead to cirrhosis and hepatocellular carcinoma (HCC)....

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
18.

Ovarian steroidogenesis

The ovarian steroids, 17-beta estradiol (E2) and progesterone (P4), are critical for normal uterine function, establishment and maintenance of pregnancy, and mammary gland development. Furthermore, the local effects that are essential for normal ovarian physiology are dependent on...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
19.

Ovarian steroidogenesis

The ovarian steroids, 17-beta estradiol (E2) and progesterone (P4), are critical for normal uterine function, establishment and maintenance of pregnancy, and mammary gland development. Furthermore, the local effects that are essential for normal ovarian physiology are dependent on...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
20.

regulation of RNA biosynthetic process

Any process that modulates the frequency, rate or extent of RNA biosynthetic process. Synonyms: regulation of RNA anabolism; regulation of RNA biosynthesis; regulation of RNA formation; regulation of RNA synthesis;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
755247
GO
: GO:2001141

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