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Items: 12

1.

cellular response to UV

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
503844
GO
: GO:0034644
2.

oxidized purine nucleobase lesion DNA N-glycosylase activity

Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination...

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
492810
GO
: GO:0008534
3.

nucleotide-excision repair, DNA incision, 5'-to lesion

The endonucleolytic cleavage of the damaged strand of DNA 5' to the site of damage. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound. The incision follows the incision formed 3' to the site of damage....

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
491257
GO
: GO:0006296
4.

nucleotide-excision repair, DNA incision, 3'-to lesion

The endonucleolytic cleavage of the damaged strand of DNA 3' to the site of damage. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound. The incision precedes the incision formed 5' to the site of damage....

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
491256
GO
: GO:0006295
5.

base-excision repair, AP site formation

The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
491248
GO
: GO:0006285
6.

base-excision repair

In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Synonym: BER;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
491247
GO
: GO:0006284
7.

mitochondrion

A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. Synonym: mitochondria;

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
489659
GO
: GO:0005739
8.

DNA-(apurinic or apyrimidinic site) lyase activity

Catalysis of the cleavage of the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. Synonyms: AP endonuclease class I activity; AP lyase activity; AP site-DNA...

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
489393
GO
: GO:0003906
9.

oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity

Catalysis of the removal oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar. The reaction involves formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination...

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
487000
GO
: GO:0000703
10.

nucleotide-excision repair factor 3 complex

One of several protein complexes involved in nucleotide-excision repair; possesses endodeoxynuclease and DNA helicase activities. In S. cerevisiae, it is composed of Rad2p and the core TFIIH-Ssl2p complex (core TFIIH is composed of Rad3p, Tfb1p, Tfb2p, Ssl1p, Tfb4p and Tfb5p. Note...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
486652
GO
: GO:0000112
11.

nucleotide-excision repair factor 1 complex

One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and endodeoxynuclease activities. In S. cerevisiae, it is composed of Rad1p, Rad10p, and Rad14p; in human the subunits are ERCC4/XPF, ERCC1 and XPA, respectively. Synonyms: NEF1...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
486650
GO
: GO:0000110
12.

single-stranded DNA endodeoxyribonuclease activity

Catalysis of the hydrolysis of ester linkages within a single-stranded deoxyribonucleic acid molecule by creating internal breaks. Synonyms: single-stranded DNA specific endodeoxyribonuclease activity; ssDNA-specific endodeoxyribonuclease activity;

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
486566
GO
: GO:0000014

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