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1.

U2-type catalytic step 1 spliceosome

A spliceosomal complex that is formed by the displacement of the U1 and U4 snRNPs from the precatalytic spliceosome; the U2, U5 and U6 snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome,...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
515932
GO
: GO:0071006
2.

Prp19 complex

A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
487198
GO
: GO:0000974
3.

first spliceosomal transesterification activity

Catalysis of the first transesterification reaction of spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron...

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
486870
GO
: GO:0000384

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