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Accession: PRJNA148127 ID: 148127

Eosinophil specific transcriptome in homeostatic intestine and lung (house mouse)

See Genome Information for Mus musculus
Objective: To study the physiological role of eosinophils in the GI tract and lung under homeostatic conditions, Method: we analyzed tissue-specific eosinophil gene expression patterns by genome-wide expression microarray analysis using RNA isolated from FACS-sorted eosinophils from the small intestine or lung of naive BALB/cmice (Live eosinophils were identified as DAPI-CCR3+Siglec-F+CD45+CD4-CD8a-CD19-B220-SSChigh cells). More...
Project Type:Transcriptome or Gene expression
Attributes:Scope: Multiisolate; Material: Transcriptome; Capture: Whole; Method type: Array
Relevance:Model Organism
Other Accessions:GEO:GSE33807
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots284456
Data volume, Processed Mbytes5
Data volume, Supplementary Mbytes36
Publications:
  • Wen T et al., "The pan-B cell marker CD22 is expressed on gastrointestinal eosinophils and negatively regulates tissue eosinophilia.", J Immunol, 2011 Dec 21;188(3):1075-82
Submission:
Registration date: 23-Nov-2011
Rothenberg, Allergy, Cincinnati Children's Hospital Medical Center

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