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Accession: PRJNA139127 ID: 139127

Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors (human)

See Genome Information for Homo sapiens
Here, we report synergistic inhibition of glycogen synthase kinase 3 (GSK3), transforming growth factor β (TGF β), and Notch signaling pathways by small molecules can efficiently convert monolayer cultured hESCs into homogenous primitive neuroepithelium within one week under chemically defined condition. More...
Project Type:Transcriptome or Gene expression
Attributes:Scope: Multiisolate; Material: Transcriptome; Capture: Whole; Method type: Array
Relevance:Medical
Other Accessions:GEO:GSE28595
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots147156
Data volume, Processed Mbytes4
Data volume, Supplementary Mbytes1
Publications:
  • Li W et al., "Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors.", Proc Natl Acad Sci U S A, 2011 Apr 27;108(20):8299-304
Submission:
Registration date: 28-Apr-2011
The Scripps Research Institute

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