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Accession: PRJNA127043 ID: 127043

The transcription factors STAT5a/b negatively regulate cell proliferation through the activation of cdkn2b and cdkn1a expression (house mouse)

See Genome Information for Mus musculus
Although the cytokine-inducible transcription factors STAT5a/b promote proliferation of a wide range of cell types, there are cell- and context specific cases in which loss of STAT5a/b results in enhanced cell proliferation. More...
Project Data Type:Transcriptome or Gene expression
Attributes:Scope: Multiisolate; Material: Transcriptome; Capture: Whole; Method type: Array
Relevance:Model Organism
Other Accessions:GEO:GSE21861
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots360808
Data volume, Processed Mbytes7
Data volume, Supplementary Mbytes120
Publications:
  • Yu JH et al., "The transcription factors signal transducer and activator of transcription 5A (STAT5A) and STAT5B negatively regulate cell proliferation through the activation of cyclin-dependent kinase inhibitor 2b (Cdkn2b) and Cdkn1a expression.", Hepatology, 2010 Nov;52(5):1808-18
Submission:
Registration date: 15-Nov-2010
Genomics Core Lab, MCL, NIDDK/NIH

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