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Accession: PRJNA126489 ID: 126489

Genome-wide analysis of skeletal muscle gene expression in Lin28A Tg mice (house mouse)

See Genome Information for Mus musculus
To identify mechanisms involved in growth and glucose metabolism, we performed whole genome mRNA expression analysis in five week old quadraceps muscle from 2 CD-1 background male Lin28A Tg and 2 WT littermates (all male) in which there was 7 fold overexpression of Lin28A, a RNA binding protein that enhances Igf2 translation and suppresses the let-7 microRNA biogenesis. More...
Project Type:Transcriptome or Gene expression
Attributes:Scope: Multiisolate; Material: Transcriptome; Capture: Whole; Method type: Array
Relevance:Model Organism
Other Accessions:GEO:GSE21226
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots72388
Data volume, Processed Mbytes2
Data volume, Supplementary Mbytes2
Publications:
  • Zhu H et al., "Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies.", Nat Genet, 2010 May 30;42(7):626-30
Submission:
Registration date: 7-Apr-2010
George Daley Lab, Hematology/Oncology, Children's Hospital of Boston

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