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Accession: PRJNA125485 ID: 125485

Activation or maintenance of a leukemia stem cell self-renewal pathway in downstream myeloid cells (house mouse)

See Genome Information for Mus musculus
Activation or maintenance of a leukemia stem cell self-renewal pathway in downstream myeloid cells is an important component of AML development We generated either MLL-AF9 mediated murine leukemias that originate from committed progenitor (GMP) cells or Hoxa9/Meis1a mediated murine leukemias that originate from hematopoietic stem cells (HSC). More...
Project Data Type: Transcriptome or Gene expression
Attributes:Scope: Multiisolate; Material: Transcriptome; Capture: Whole; Method type: Array
Relevance:Model Organism
Other Accessions:GEO:GSE20377
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets2
GEO Data Details
ParameterValue
Data volume, Spots340350
Data volume, Processed Mbytes8
Data volume, Supplementary Mbytes32
Publications:
  • Wang Y et al., "The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.", Science, 2010 Mar 26;327(5973):1650-3
Submission:
Registration date: 15-Mar-2010
Armstrong Lab, Pediatric Oncology, Dana-Farber Cancer Institute

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