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Accession: PRJNA121759 ID: 121759

Expression data identifying hypermethylated genes associated with acquired cisplatin resistance (human)

See Genome Information for Homo sapiens
Treatment-related DNA hypermethylation may play a role in creating drug resistant phenotypes by inactivating genes that are required for cytotoxicity, but there have been no genome-wide studies to systematically investigate methylation of individual genes following exposure to chemotherapy. More...
Project Type:Transcriptome or Gene expression
Attributes:Scope: Multiisolate; Material: Transcriptome; Capture: Whole; Method type: Array
Relevance:Medical
Other Accessions:GEO:GSE19397
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots267396
Data volume, Processed Mbytes8
Data volume, Supplementary Mbytes20
Publications:
  • Chang X et al., "Identification of hypermethylated genes associated with cisplatin resistance in human cancers.", Cancer Res, 2010 Mar 9;70(7):2870-9
Submission:
Registration date: 1-Apr-2010
David Sidransky, Otolaryngology, Johns Hopkins University

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