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Accession: PRJNA112973 ID: 112973

A TGFB Responsive Gene Expression Signature is Associated With More Severe Skin and Lung Disease in Diffuse Scleroderma (human)

See Genome Information for Homo sapiens
Primary dermal fibroblasts from patients with dSSc and healthy controls were treated with TGF beta for up to 24h and the genome-wide patterns of gene expression measured on DNA microarrays. More...
Project Data Type:Transcriptome or Gene expression
Attributes:Scope: Multiisolate; Material: Transcriptome; Capture: Whole; Method type: Array
Relevance:Medical
Other Accessions:GEO:GSE12493
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots749576
Data volume, Processed Mbytes14
Data volume, Supplementary Mbytes231
Publications:
  • Sargent JL et al., "A TGFbeta-responsive gene signature is associated with a subset of diffuse scleroderma with increased disease severity.", J Invest Dermatol, 2009 Oct 8;130(3):694-705
Submission:
Registration date: 19-Aug-2008
Whitfield, Genetics, Dartmouth Medical School

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