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Accession: PRJNA103283 ID: 103283

An E2F1-Dependent Gene Expression Program That Determines the Balance Between Proliferation and Cell Death (Norway rat)

See Genome Information for Rattus norvegicus
E2F1 has been shown to induce both proliferation and apoptosis. We now show that PI3K/Akt signaling regulates the balance of these events by specifically blocking expression of genes in the E2F1 apoptotic program but not the proliferative program. More...
Project Data Type: Transcriptome or Gene expression
Attributes:Scope: Multiisolate; Material: Transcriptome; Capture: Whole; Method type: Array
Relevance:Model Organism
Other Accessions:GEO:GSE9496
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots175153
Data volume, Processed Mbytes6
Data volume, Supplementary Mbytes28
Publications:
  • Hallstrom TC et al., "An E2F1-dependent gene expression program that determines the balance between proliferation and cell death.", Cancer Cell, 2008 Jan;13(1):11-22
Submission:
Registration date: 2-Nov-2007
Pediatrics, University of Minnesota

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