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Search Database of PSI-BLAST Profiles with IMPALA
The NCBI BLAST group has developed IMPALAsoftware to match a protein sequence against a library of score matrices stored from PSI-BLAST. A standalone version of the IMPALA suite of programs is included within the standalone BLAST distributions found at ftp://ncbi.nlm.nih.gov/blast/executables/.
A Web-based IMPALA search is available on the BLOCKS server at the Fred Hutchinson Cancer Center (blocks.fhcrc.org/blocks/impala.html). Any protein can be searched against a library of score matrices derived from the BLOCKS database.
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