Dazzling Graphics
with Cn3D 3.0
HomoloGene:
Clusters of Clusters
Fly Genome
Deposited in GenBank
Fly Genome Deposited in GenBank
The Drosophila genome sequence described in Science (Mar 2000; 287, 2185–95) is publicly available in GenBank. The genome, sequenced jointly by scientists at Celera Genomics and the Berkeley Drosophila Genome Project (BDGP), was deposited in the form of more than 700 “scaffolds” consisting of annotated, ordered sets of contigs having gaps of known length. Approximately 134 scaffolds, representing 98% of the genome, have been mapped to a chromosome and these mappings appear in the GenBank record with a “/chromosome” qualifier in the source feature field.
Many scaffolds contain unsequenced gaps of known length, indicated by the appropriate number of Ns. The sequence spanning the gaps will be filled, primarily by the BDGP, from one end of the genome to the other, in the coming months. As each chromosome is completed, it will be completely reannotated, reviewed, and updated with a complete, consistent set of annotated records. In the meantime, the BDGP plans to provide regular unannotated updates to NCBI of the most recent versions of the scaffold sequences. These updates will be available from the NCBI FTP site. NCBI will also align the annotated GenBank records to the most recent unannotated versions of the scaffolds in order to combine the annotation available from the initial release with the most recent sequence data.—JO, DW
