Dazzling Graphics
with Cn3D 3.0
HomoloGene:
Clusters of Clusters
Fly Genome Deposited
in GenBank
Drosophila Finds
New Home Page
Drosophila Finds a Home Page at NCBI
NCBI has combined a gateway to the complete genomic sequence of the fruit fly, an array of links to related Drosophila resources such as FlyBase and GadFly, and a mix of pre-computed analyses conducted at NCBI, to produce a special Drosophila Web page to serve as a springboard for the analysis of the fly genome sequenced jointly by Celera Genomics and the Berkeley Drosophila Genome Project.
The Genome Map Viewer
The genome of the fruit fly is accessible through five chromosome links, each of which invokes NCBI’s new Genome Map Viewer to provide access to the sequence data. Users can select from five different maps, which run the gamut from physical maps showing chromosomal banding patterns, to sequence maps with links to GenBank records. Using a query box at the top of the main Drosophila page, it is possible to perform text searches followed by protein neighbor searches in which the results are graphically mapped onto the Drosophila chromosomes.
NCBI Analysis
Pre-computed BLAST comparisons between protein sequences derived from the Drosophila sequence and all protein sequences in the BLAST non-redundant database can be accessed through a link on the Drosophila page.
In addition, a one can generate a 2-dimensional dot plot showing the similarity of the set of Drosophila proteins to the protein sets of any two organisms or taxa. A Related Structures link on the Drosophila page leads to a listing of Drosophila protein sequences with significant similarity to the sequences of proteins with known structure. Using NCBI’s Cn3D macromolecular viewer it is possible to view 3-D images of the Drosophila protein sequences superimposed upon protein structures to which they bear sequence similarity.
The Drosophila Web page can be reached through a link on NCBI’s Genomic Biology Web page at www.ncbi.nlm.nih.gov/Genomes/index.html.—DW
NCBI’s Human Genome Map Viewer can display up to seven parallel chromosomal maps simultaneously. The maps displayed can be selected from a set of 19, and include cytogenetic maps, such as G-banding chromosomal ideograms, sequence-based maps, such as those showing contig and clone information, and radiation hybrid maps, such as the G3 and GB4 maps used to construct GeneMap ’99. To take a broad view of the human genome click on the Map Viewer link on NCBI’s Human Genome Resources Web page at www.ncbi.nlm.nih.gov/genome/guide/.
A Map Viewer for the Human Genome
