Gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6 (Gabra6)

Restricted Expression:

brain [show more like this]

juvenile [show more like this]

EST Profile:

Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]

GEO Profiles:

Experimental gene expression data (Gene Expression Omnibus).

cDNA Sources:

brain; mixed

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Finding cDNAs

UGID:257908 UniGene Mm.4915 Mus musculus (mouse) Gabra6

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Gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6 (Gabra6)

Mouse protein-coding gene Gabra6. Represented by 55 ESTs from 13 cDNA libraries. EST representation biased toward brain; juvenile. Corresponds to 2 reference sequences (different isoforms). [UniGene 257908 - Mm.4915]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_001093111.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Gabra6 gene product	M. musculus	100.0	452
NP_000802.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	GABRA6 gene product	H. sapiens	92.3	452
XP_002667403.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: gamma-aminobutyric acid receptor subunit alpha-6	D. rerio	80.6	418
NP_001087431.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	gamma-aminobutyric acid (GABA) A receptor, alpha 2 precursor	X. laevis	71.9	430
Other hits (2 of 23) [Show all]		Species	Id(%)	Len(aa)
NP_068613.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	gamma-aminobutyric acid receptor subunit alpha-6 precursor	R. norvegicus	97.1	452
XP_001086065.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: gamma-aminobutyric acid receptor subunit alpha-6	M. mulatta	92.7	448

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	11
Map position:	11 A5\|11 25.03 cM
UniSTS entry:	Chr 11	Gabra6
UniSTS entry:	Chr 11	X51986

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

AK137331.1	Mus musculus 16 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:9630012C19 product:gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 6, full insert sequence	P
AK135145.1	Mus musculus 10 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:6530415G18 product:gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 6, full insert sequence	P
BC145702.1	Mus musculus gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 6, mRNA (cDNA clone MGC:175589 IMAGE:40131005), complete cds	P
NM_001099641.1	Mus musculus gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6 (Gabra6), transcript variant 1, mRNA	PA
BC145158.1	Mus musculus gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 6, mRNA (cDNA clone MGC:178717 IMAGE:9053709), complete cds	P
X51986.1	Mouse mRNA for GABAA receptor alpha-6 subunit	P
NM_008068.2	Mus musculus gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6 (Gabra6), transcript variant 2, mRNA	PA
AF256197.1	Mus musculus strain C57BL/6J GABA-A receptor alpha-6 subunit protein long splice variant (Gabra6) mRNA, complete cds	P
AF256198.1	Mus musculus strain DBA/2J GABA-A receptor alpha-6 subunit protein long splice variant (Gabra6) mRNA, complete cds	P

EST sequences (10 of 55) [Show all sequences]

BY373598.1	Clone G630027C02	brain	3' read	A
BY722419.1	Clone 9630012C19	brain	5' read	P
BY125019.1	Clone L630032H01	brain	5' read
CB524625.1	Clone IMAGE:6846781	brain	5' read	A
CO044772.1	Clone UI-M-AH0-acw-a-01-0-UI	brain	3' read	PA
CJ050477.1	Clone 6530415G18	brain	5' read	P
AV028875.1	Clone 1500002A07	brain
AV033558.1	Clone 1500040P17	brain
AV033810.1	Clone 1500041P19	brain
AI839865.1	Clone UI-M-AH0-acw-a-01-0-UI	brain	3' read	PA

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria