Natriuretic peptide type A (Nppa)

Restricted Expression:

heart [show more like this]

EST Profile:

Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]

GEO Profiles:

Experimental gene expression data (Gene Expression Omnibus).

cDNA Sources:

heart; embryonic tissue; mixed; uncharacterized tissue; kidney; muscle

NCBI

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Finding cDNAs

UGID:4418474 UniGene Mm.482123 Mus musculus (mouse) Nppa

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Natriuretic peptide type A (Nppa)

Mouse protein-coding gene Nppa. Represented by 130 ESTs from 26 cDNA libraries. EST representation biased toward heart. Corresponds to reference sequence NM_008725.2. [UniGene 4418474 - Mm.482123]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_032751.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Nppa gene product	M. musculus	100.0	151
NP_006163.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	natriuretic peptides A preproprotein	H. sapiens	86.8	150
NP_001090387.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	natriuretic peptide A precursor	X. laevis	49.3	141
Other hits (2 of 11) [Show all]		Species	Id(%)	Len(aa)
NP_036744.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Nppa gene product	R. norvegicus	97.4	151
XP_850357.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: natriuretic peptides A	C. lupus familiaris	87.9	148

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	4
Map position:	4 E2\|4 78.66 cM
UniSTS entry:	Chr 4	Nppa
UniSTS entry:	Chr 4	PMC123178P1
UniSTS entry:	Chr 4	PMC316718P1
UniSTS entry:	Chr 4	Nppa
UniSTS entry:	Chr 4	PMC26660P3
UniSTS entry:	Chr 4	Nppa

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (3)

BC089615.1	Mus musculus natriuretic peptide precursor type A, mRNA (cDNA clone MGC:107674 IMAGE:6755676), complete cds	PA
NM_008725.2	Mus musculus natriuretic peptide type A (Nppa), mRNA	PA
AK147180.1	Mus musculus 16 days embryo heart cDNA, RIKEN full-length enriched library, clone:I920194N08 product:Atrial natriuretic factor precursor (ANF) (Atrial natriuretic peptide) (ANP) (Prepronatriodilatin), full insert sequence	P

EST sequences (10 of 130) [Show all sequences]

CA786685.1	Clone IMAGE:6756430	heart	5' read	P
CA786783.1	Clone IMAGE:6757404	heart	5' read	P
CA786845.1	Clone IMAGE:6757567	heart	5' read	P
CA786864.1	Clone IMAGE:6757610	heart	5' read	PA
CA787031.1	Clone IMAGE:6757872	heart	5' read	P
CA787043.1	Clone IMAGE:6757888	heart	5' read	P
CA787204.1	Clone IMAGE:6758570	heart	5' read	P
CA787217.1	Clone IMAGE:6758591	heart	5' read	P
CA787232.1	Clone IMAGE:6758625	heart	5' read	P
CA787277.1	Clone IMAGE:6758716	heart	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria