> Large tumor suppressor 2 (Lats2)
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UGID:1195813     UniGene Mm.347899     Mus musculus (mouse)   Lats2 Order cDNA clone, Links
Large tumor suppressor 2 (Lats2)

Mouse protein-coding gene Lats2. Represented by 268 ESTs from 118 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 1195813 - Mm.347899]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_056586.2 Lats2 gene product M. musculus 100.0 1041
NP_055387.2 LATS2 gene product H. sapiens 91.6 1087
NP_001121728.1 lats2 gene product D. rerio 76.2 1077
NP_001087838.1 LATS, large tumor suppressor, homolog 1 X. laevis 65.2 1085
NP_014238.3 Cbk1p S. cerevisiae 53.8 463
XP_001690043.1 serine/threonine protein kinase 19 C. reinhardtii 52.8 441
NP_524170.2 tricornered, isoform A D. melanogaster 51.9 426
NP_193171.2 AGC (cAMP-dependent, cGMP-dependent and protein kinase C) kinase family protein A. thaliana 50.8 533
NP_492699.1 Protein WTS-1 C. elegans 49.3 811
XP_962150.1 serine/threonine-protein kinase orb6 N. crassa 45.6 463
Other hits (2 of 62) [Show all]SpeciesId(%)Len(aa)
NP_001100737.1 serine/threonine-protein kinase LATS2 R. norvegicus 96.9 1041
XP_003913688.1 PREDICTED: serine/threonine-protein kinase LATS2 P. anubis 91.9 1085

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: embryonic tissue; brain; eye; testis; mixed; skin; spleen; spinal cord; mammary gland; uncharacterized tissue; prostate; adipose tissue; extraembryonic tissue; lymph node; heart; kidney; lung; pancreas; thymus; vagina; ovary; bone; bladder; connective tissue; oviduct; salivary gland; liver; sympathetic ganglion; blood
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 14
Map position: 14 C3|14
UniSTS entry: Chr 14 AW228608
UniSTS entry: Lats2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (26)

AK029966.1 Mus musculus adult male testis cDNA, RIKEN full-length enriched library, clone:4932411G09 product:large tumor suppressor 2, full insert sequence P
AK081190.2 Mus musculus 10 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:B930098K05 product:large tumor suppressor 2, full insert sequence P
AK029870.1 Mus musculus adult male testis cDNA, RIKEN full-length enriched library, clone:4931418E17 product:large tumor suppressor 2, full insert sequence P
AK029242.1 Mus musculus 0 day neonate head cDNA, RIKEN full-length enriched library, clone:4831438F24 product:large tumor suppressor 2, full insert sequence P
BC040025.1 Mus musculus large tumor suppressor 2, mRNA (cDNA clone IMAGE:5146973) P
BC024819.2 Mus musculus large tumor suppressor 2, mRNA (cDNA clone IMAGE:5360539) P
AB028209.1 Mus musculus mRNA, up-regulated by FUS-ERG, 3' region, cDNA fragment: C14G220 A
BC053028.1 Mus musculus large tumor suppressor 2, mRNA (cDNA clone MGC:62249 IMAGE:6409832), complete cds PA
AK214107.1 Mus musculus cDNA, clone:Y2G0130K20, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000069482, based on BLAT search P
AK214001.1 Mus musculus cDNA, clone:Y2G0130E06, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000069482, based on BLAT search
AK213007.1 Mus musculus cDNA, clone:Y2G0126N10, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000022531, based on BLAT search
AK198862.1 Mus musculus cDNA, clone:Y1G0129G12, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000069482, based on BLAT search
AK193851.1 Mus musculus cDNA, clone:Y1G0113I22, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000069482, based on BLAT search
AK191566.1 Mus musculus cDNA, clone:Y1G0106E15, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000022531, based on BLAT search
AK190438.1 Mus musculus cDNA, clone:Y1G0102M03, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000069482, based on BLAT search P
AK183287.1 Mus musculus cDNA, clone:Y0G0125G01, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000069482, based on BLAT search P
AK178361.1 Mus musculus cDNA, clone:Y0G0106G16, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000069482, based on BLAT search P
AK164789.1 Mus musculus 10 days lactation, adult female mammary gland cDNA, RIKEN full-length enriched library, clone:D730034C24 product:large tumor suppressor 2, full insert sequence P
AK137436.1 Mus musculus 16 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:9630060M07 product:large tumor suppressor 2, full insert sequence P
AK163607.1 Mus musculus 4 days neonate male adipose cDNA, RIKEN full-length enriched library, clone:B430302L02 product:large tumor suppressor 2, full insert sequence P
AK161243.1 Mus musculus adult male testis cDNA, RIKEN full-length enriched library, clone:4921505H05 product:large tumor suppressor 2, full insert sequence P
NM_153382.1 Mus musculus large tumor suppressor 2 (Lats2), transcript variant B, mRNA PA
AB023958.1 Mus musculus MmLATS2 mRNA for warts/lats-like kinase, complete cds PA
NM_015771.2 Mus musculus large tumor suppressor 2 (Lats2), transcript variant A, mRNA PA
AY015062.1 Mus musculus LATS2C (Lats2) mRNA, complete cds, alternatively spliced PA
AY015061.1 Mus musculus LATS2B (Lats2) mRNA, complete cds, alternatively spliced PA

EST sequences (10 of 268) [Show all sequences]

BY059916.1 Clone I920004G02 heart 5' read
BY086656.1 Clone K630062F11 extraembryonic tissue 5' read
BY091693.1 Clone K630088D16 extraembryonic tissue 5' read
BY309244.1 Clone I320009A21 uncharacterized tissue 5' read
BY322381.1 Clone L030014A10 connective tissue 5' read
BY322393.1 Clone L030014B10 connective tissue 5' read
BY358788.1 Clone 3221402N19 embryonic tissue 3' read A
BY358915.1 Clone 3321404L02 embryonic tissue 3' read A
BY414262.1 Clone I920001I02 kidney 3' read A
BY419379.1 Clone I920043I06 kidney 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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