Nitric oxide synthase 2, inducible (Nos2)

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UGID:256918 UniGene Mm.2893 Mus musculus (mouse) Nos2

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Nitric oxide synthase 2, inducible (Nos2)

Mouse protein-coding gene Nos2. Represented by 22 ESTs from 10 cDNA libraries. Corresponds to reference sequence NM_010927.3. [UniGene 256918 - Mm.2893]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_035057.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Nos2 gene product	M. musculus	100.0	1143
NP_000616.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	NOS2 gene product	H. sapiens	80.9	1150
NP_001098407.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	nos2a gene product	D. rerio	58.2	1053
NP_001079155.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	nitric oxide synthase 1 (neuronal)	X. laevis	53.2	1120
NP_523541.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	nitric oxide synthase, isoform A	D. melanogaster	45.0	1109
Other hits (2 of 37) [Show all]		Species	Id(%)	Len(aa)
NP_036743.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Nos2 gene product	R. norvegicus	94.1	1146
NP_001137162.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	NOS2 gene product	S. scrofa	83.3	1056

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	uncharacterized tissue; skin; brain; mixed; mammary gland; heart

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	11
Map position:	11 B5\|11 46.74 cM
UniSTS entry:		GDB:437694
UniSTS entry:		Nos2
UniSTS entry:	Chr 11	PMC122623P2
UniSTS entry:	Chr 11	PMC186377P3
UniSTS entry:		Nos2
UniSTS entry:		Nos2
UniSTS entry:		Nos2
UniSTS entry:	Chr 11	Nos2
UniSTS entry:	Chr 11	M84373

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

BC062378.1	Mus musculus nitric oxide synthase 2, inducible, mRNA (cDNA clone MGC:68162 IMAGE:4978648), complete cds	PA
GU451261.1	Mus musculus strain MF1 nitric oxide synthase 2 (Nos2) mRNA, partial cds	P
M87039.1	Mus musculus nitric oxide synthase (iNOSl) mRNA, complete cds	P
M84373.1	Murine nitric oxide synthase (MAC-NOS) gene, complete cds	P
M92649.1	Mus musculus nitric oxide synthase mRNA	PA
U43428.1	Mus musculus inducible nitric oxide synthase mRNA, complete cds	P
AF065919.1	Mus musculus strain BALB/cByJ nitric oxide synthase 2 (Nos2) mRNA, complete cds	P
AF065920.1	Mus musculus strain DBA/2J nitric oxide synthase 2 (Nos2) mRNA, complete cds	P
AF065921.2	Mus musculus strain B10.S/J nitric oxide synthase 2 (Nos2) mRNA, complete cds	P
AF065922.2	Mus musculus strain SJL/J nitric oxide synthase 2 (Nos2) mRNA, complete cds	P
AF065923.2	Mus musculus strain NOD/LtJ nitric oxide synthase 2 (Nos2) mRNA, complete cds	P
NM_010927.3	Mus musculus nitric oxide synthase 2, inducible (Nos2), mRNA	P
AY090567.1	Mus musculus strain ICR inducible nitric oxide synthase (Nos2) mRNA, complete cds	P

EST sequences (10 of 22) [Show all sequences]

BY174336.1	Clone F630001B15	uncharacterized tissue	5' read	P
BY175860.1	Clone F630014I02	uncharacterized tissue	5' read
BY176421.1	Clone F630019B03	uncharacterized tissue	5' read
BY181954.1	Clone F630049F19	uncharacterized tissue	5' read	P
BY186129.1	Clone F630217C10	uncharacterized tissue	5' read	P
BY192714.1	Clone F630329C06	uncharacterized tissue	5' read
BY193291.1	Clone F730002N07	skin	5' read
BY202059.1	Clone F730110L21	skin	5' read	P
BY202308.1	Clone F730112F05	skin	5' read	P
BY203786.1	Clone F730120F11	skin	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria