Glial fibrillary acidic protein (Gfap)

Restricted Expression:

adult [show more like this]

EST Profile:

Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]

GEO Profiles:

Experimental gene expression data (Gene Expression Omnibus).

cDNA Sources:

uncharacterized tissue; brain; spinal cord; embryonic tissue; mixed; liver; eye; inner ear

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Finding cDNAs

UGID:256227 UniGene Mm.1239 Mus musculus (mouse) Gfap

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Glial fibrillary acidic protein (Gfap)

Mouse protein-coding gene Gfap. Represented by 392 ESTs from 27 cDNA libraries. EST representation biased toward adult. Corresponds to 2 reference sequences (different isoforms). [UniGene 256227 - Mm.1239]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_034407.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Gfap gene product	M. musculus	100.0	429
NP_002046.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	GFAP gene product	H. sapiens	95.1	431
NP_571448.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	gfap gene product	D. rerio	77.0	383
NP_001080908.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	vimentin-1/2	X. laevis	61.9	422
Other hits (2 of 22) [Show all]		Species	Id(%)	Len(aa)
NP_058705.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Gfap gene product	R. norvegicus	98.4	429
NP_776490.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	GFAP gene product	B. taurus	96.0	427

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	11
Map position:	11 D\|11 66.48 cM
UniSTS entry:		Gfap
UniSTS entry:	Chr 11	PMC125376P2
UniSTS entry:		Gfap
UniSTS entry:		Gfap
UniSTS entry:		Gfap
UniSTS entry:		Gfap
UniSTS entry:		Gfap
UniSTS entry:	Chr 11	Gfap
UniSTS entry:		K01347
UniSTS entry:		RH131871

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

AK079577.1	Mus musculus adult male hypothalamus cDNA, RIKEN full-length enriched library, clone:A230103O17 product:glial fibrillary acidic protein, astrocyte, full insert sequence	P
NM_010277.3	Mus musculus glial fibrillary acidic protein (Gfap), transcript variant 2, mRNA	PA
BC103571.1	Mus musculus glial fibrillary acidic protein, mRNA (cDNA clone IMAGE:40045440), partial cds	P
BC100737.1	Mus musculus glial fibrillary acidic protein, mRNA (cDNA clone IMAGE:40045433), partial cds	P
BC100728.1	Mus musculus glial fibrillary acidic protein, mRNA (cDNA clone IMAGE:40045436), partial cds	P
AK140151.1	Mus musculus adult male corpora quadrigemina cDNA, RIKEN full-length enriched library, clone:B230315D14 product:glial fibrillary acidic protein, full insert sequence	P
BC101968.1	Mus musculus glial fibrillary acidic protein, mRNA (cDNA clone IMAGE:40045438), partial cds	P
DQ887822.1	Mus musculus glial fibrillary acidic protein mRNA, partial cds	P
EF042974.1	Mus musculus glial fibrillary acidic protein (Gfap) mRNA, partial cds	P
EF101554.1	Mus musculus glial fibrillary acidic protein (Gfap) mRNA, partial cds	P
BC139358.1	Mus musculus glial fibrillary acidic protein, mRNA (cDNA clone MGC:170985 IMAGE:8862380), complete cds	P
BC139357.1	Mus musculus glial fibrillary acidic protein, mRNA (cDNA clone MGC:170984 IMAGE:8862379), complete cds	P
NM_001131020.1	Mus musculus glial fibrillary acidic protein (Gfap), transcript variant 1, mRNA	PA
M25937.1	Mouse glial fibrillary acidic protein mRNA, 3' end	P
K01347.1	Mouse glial fibrillary acidic protein (GFAP) mRNA	P
AF332062.1	glial fibrillary acidic protein [Mus musculus], mRNA sequence	P
AF332061.1	glial fibrillary acidic protein [Mus musculus], mRNA sequence	P

EST sequences (10 of 392) [Show all sequences]

BY229875.1	Clone F930011F15	inner ear	5' read	P
BY126127.1	Clone L630043A22	brain	5' read	P
CA882935.1	Clone NIA:B0100A03_IMAGE:30093794	uncharacterized tissue	3' read	A
CA882977.2	Clone NIA:B0100C07_IMAGE:30093822	uncharacterized tissue	5' read	P
CA883003.2	Clone NIA:B0100D11_IMAGE:30093838	uncharacterized tissue	5' read	P
CA883010.1	Clone NIA:B0100E05_IMAGE:30093844	uncharacterized tissue	3' read	A
CA883011.2	Clone NIA:B0100E05_IMAGE:30093844	uncharacterized tissue	5' read	P
CA883018.2	Clone NIA:B0100E09_IMAGE:30093848	uncharacterized tissue	5' read	P
CA883037.2	Clone NIA:B0100F09_IMAGE:30093860	uncharacterized tissue	5' read	P
CA883039.2	Clone NIA:B0100F11_IMAGE:30093862	uncharacterized tissue	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria