Thiopurine methyltransferase (Tpmt)

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UGID:258948 UniGene Mm.10169 Mus musculus (mouse) Tpmt

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Thiopurine methyltransferase (Tpmt)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
NP_058065.2	thiopurine S-methyltransferase	M. musculus	100.0	239
NP_000358.1	thiopurine S-methyltransferase	H. sapiens	81.6	244
NP_001002569.2	thiopurine S-methyltransferase	D. rerio	57.5	227
NP_001087908.1	MGC84277 protein	X. laevis	56.1	229

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	kidney; brain; embryonic tissue; mixed; ovary; heart; liver; bone marrow; eye; pancreas; testis; connective tissue; muscle; thymus; prostate; spinal cord; inner ear

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	13
Map position:	13 A5\|13 28.0 cM
UniSTS entry:	Chr 13	AW106912

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

AK019205.1	Mus musculus 11 days embryo whole body cDNA, RIKEN full-length enriched library, clone:2700029K22 product:thiopurine methyltransferase, full insert sequence	P
AF046887.1	Mus musculus thiopurine S-methyltransferase mRNA, complete cds	P
AF037043.1	Mus musculus strain DBA/2J thiopurine S-methyltransferase (Tpmt) mRNA, complete cds	PA
AF037044.1	Mus musculus strain C57BL/6J thiopurine S-methyltransferase (Tpmt) mRNA, complete cds	P
AF037045.1	Mus musculus strain M.SPRET/EI thiopurine S-methyltransferase (Tpmt) mRNA, complete cds	P
NM_016785.2	Mus musculus thiopurine methyltransferase (Tpmt), mRNA	PA
AK002335.1	Mus musculus adult male kidney cDNA, RIKEN full-length enriched library, clone:0610008H11 product:thiopurine methyltransferase, full insert sequence	P
BC021598.1	Mus musculus thiopurine methyltransferase, mRNA (cDNA clone MGC:35956 IMAGE:5098857), complete cds	PA

EST sequences (10 of 78) [Show all sequences]

CA571066.1	Clone NIA:K0515D06_IMAGE:30065321	bone marrow	5' read	PM
CA571938.1	Clone NIA:K0526H12_IMAGE:30066431	bone marrow	5' read	PM
BY070227.1	Clone I920071L03	liver	5' read	P
BY332630.1	Clone L130026D18	connective tissue	5' read	P
BY423970.1	Clone I920071L03	liver	3' read	A
BY702872.1	Clone 0610008H11	kidney	5' read	P
BY707734.1	Clone 1810037D09	pancreas	5' read	P
BY711463.1	Clone 2700029K22	embryonic tissue	5' read	P
CB945542.1	Clone IMAGE:30317274	testis	5' read	P
CB954306.1	Clone IMAGE:30305160	kidney	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria