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UGID:142456     UniGene Hs.98712     Homo sapiens (human)   TXNDC2
Thioredoxin domain containing 2 (spermatozoa) (TXNDC2)

Human protein-coding gene TXNDC2. Represented by 92 ESTs from 9 cDNA libraries. EST representation biased toward testis; normal; adult. Corresponds to 2 reference sequences (different isoforms). [UniGene 142456 - Hs.98712]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001091999.1 TXNDC2 gene product H. sapiens 100.0 552
NP_705739.2 Txndc2 gene product M. musculus 48.6 532
Other hits (2 of 8) [Show all]SpeciesId(%)Len(aa)
XP_001135716.1 PREDICTED: thioredoxin domain-containing protein 2 isoform 2 P. troglodytes 93.3 491
XP_003914199.1 PREDICTED: thioredoxin domain-containing protein 2 isoform 1 P. anubis 86.8 417

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: testis [show more like this]
normal [show more like this]
adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; placenta
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 18
UniSTS entry: RH92269
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

BC050132.1 Homo sapiens thioredoxin domain containing 2 (spermatozoa), mRNA (cDNA clone MGC:35026 IMAGE:5164861), complete cds PA
NM_032243.5 Homo sapiens thioredoxin domain containing 2 (spermatozoa) (TXNDC2), transcript variant 1, mRNA PA
EF560747.1 Homo sapiens clone IMAGp998K0211411 TXNDC2 protein (TXNDC2) mRNA, complete cds PA
NM_001098529.1 Homo sapiens thioredoxin domain containing 2 (spermatozoa) (TXNDC2), transcript variant 2, mRNA PA
AF080095.1 Homo sapiens sperm-specific thioredoxin (Sptrx) mRNA, complete cds P
AK097656.1 Homo sapiens cDNA FLJ40337 fis, clone TESTI2032044, moderately similar to THIOREDOXIN P
AK303045.1 Homo sapiens cDNA FLJ61503 complete cds, moderately similar to Thioredoxin domain-containing protein 2 P

EST sequences (92)

AI125222.1 Clone IMAGE:1736490 testis 3' read PA
BX281456.1 Clone IMAGp998G194412_;_IMAGE:1736490 testis P
CD557557.1 Clone IMAGE:30390325 testis 5' read P
DB040404.1 Clone TESTI2027208 testis 5' read P
DB040434.1 Clone TESTI2027248 testis 5' read P
DB028036.1 Clone TESTI2010775 testis 5' read P
DB028163.1 Clone TESTI2010960 testis 5' read P
DB028603.1 Clone TESTI2011541 testis 5' read P
DB041524.1 Clone TESTI2028621 testis 5' read P
DB041750.1 Clone TESTI2028907 testis 5' read P
DB041774.1 Clone TESTI2028937 testis 5' read P
DB029621.1 Clone TESTI2012891 testis 5' read P
DB042273.1 Clone TESTI2029578 testis 5' read P
DB036503.1 Clone TESTI2022221 testis 5' read P
DB037693.1 Clone TESTI2023766 testis 5' read
DB044145.1 Clone TESTI2032044 testis 5' read P
DB044266.1 Clone TESTI2032192 testis 5' read P
DB044465.1 Clone TESTI2032443 testis 5' read P
DB020452.1 Clone TESTI2000647 testis 5' read P
DB021013.1 Clone TESTI2001437 testis 5' read P
DB022692.1 Clone TESTI2003704 testis 5' read P
DB023655.1 Clone TESTI2004928 testis 5' read P
DB030190.1 Clone TESTI2013656 testis 5' read P
DB030736.1 Clone TESTI2014442 testis 5' read P
DB025610.1 Clone TESTI2007507 testis 5' read P
DB026083.1 Clone TESTI2008150 testis 5' read P
DB032859.1 Clone TESTI2017444 testis 5' read P
DB026796.1 Clone TESTI2009094 testis 5' read P
DB026967.1 Clone TESTI2009311 testis 5' read P
DB033347.1 Clone TESTI2018135 testis 5' read P
DB040114.1 Clone TESTI2026817 testis 5' read P
DB080661.1 Clone TESTI4026334 testis 5' read P
DB338078.1 Clone TESTI2032044 testis 3' read PA
DB050090.1 Clone TESTI2039555 testis 5' read P
DB050165.1 Clone TESTI2039644 testis 5' read P
DB050249.1 Clone TESTI2039753 testis 5' read P
DB050333.1 Clone TESTI2039858 testis 5' read P
DB052773.1 Clone TESTI2043090 testis 5' read P
DB053067.1 Clone TESTI2043474 testis 5' read P
DB056072.1 Clone TESTI2047574 testis 5' read P
DB057692.1 Clone TESTI2049972 testis 5' read P
DB058072.1 Clone TESTI2050562 testis 5' read P
DB058182.1 Clone TESTI2050734 testis 5' read P
DB058498.1 Clone TESTI2051213 testis 5' read P
DB099560.1 Clone TESTI4051284 testis 5' read P
DB099921.1 Clone TESTI4051713 testis 5' read P
DB066763.1 Clone TESTI4008194 testis 5' read P
BF996550.1 placenta P
DB516495.1 Clone H013051K05 testis 3' read PA
DB547544.1 Clone H023080L07 brain 3' read PA
DB443653.1 Clone H013011D22 testis 5' read
DB519952.1 Clone H013065N11 testis 3' read PA
DB466866.1 Clone H023024M01 brain 5' read
DB445057.1 Clone H013018E04 testis 5' read
DB523239.1 Clone H013079A02 testis 3' read PA
DB508611.1 Clone H013011D22 testis 3' read PA
DB451003.1 Clone H013051K05 testis 5' read
DB510041.1 Clone H013018E04 testis 3' read PA
DB454522.1 Clone H013065N11 testis 5' read P
DB457748.1 Clone H013079A02 testis 5' read
DB478882.1 Clone H023080L07 brain 5' read
BI460141.1 Clone IMAGE:5267836 testis 5' read P
BI463874.1 Clone IMAGE:5268459 testis 5' read P
BI562175.1 Clone IMAGE:5297849 testis 5' read P
BI826592.1 Clone IMAGE:5168602 brain 5' read P
BI828141.1 Clone IMAGE:5165689 brain 5' read P
BI828938.1 Clone IMAGE:5166841 brain 5' read P
BI829219.1 Clone IMAGE:5171312 brain 5' read P
BI831646.1 Clone IMAGE:5166500 brain 5' read P
BI831948.1 Clone IMAGE:5168171 brain 5' read P
BI831969.1 Clone IMAGE:5167810 brain 5' read P
BI832369.1 Clone IMAGE:5164861 brain 5' read P
BM553904.1 Clone IMAGE:5742221 brain 5' read P
BM554364.1 Clone IMAGE:5742487 brain 5' read P
BM559733.1 Clone IMAGE:5744383 brain 5' read P
BM563078.1 Clone IMAGE:5743795 brain 5' read
HY021092.1 Clone H04D071E07 testis P
HY025024.1 Clone H04D085H19 testis P
HY026549.1 Clone H04D090M08 testis P
HY027356.1 Clone H04D093O07 testis P
HY029719.1 Clone H04D102O08 testis
HY029851.1 Clone H04D103I05 testis P
HY034161.1 Clone H04D118B11 testis P
HY053308.1 Clone H04D188P22 testis P
HY197918.1 Clone H04D047I05 testis P
HY204113.1 Clone H04D071E07 testis P
HY208708.1 Clone H04D085H19 testis P
HY211490.1 Clone H04D093O07 testis P
HY214236.1 Clone H04D102O08 testis P
HY214428.1 Clone H04D103I05 testis P
HY233034.1 Clone H04D163E03 testis P
HY241236.1 Clone H04D188P22 testis P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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