> Rho guanine nucleotide exchange factor (GEF) 10 (ARHGEF10)
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UGID:142400     UniGene Hs.98594     Homo sapiens (human)   ARHGEF10 Order cDNA clone, Links
Rho guanine nucleotide exchange factor (GEF) 10 (ARHGEF10)

Human protein-coding gene ARHGEF10. Represented by 281 ESTs from 137 cDNA libraries. Corresponds to reference sequence NM_014629.2. [UniGene 142400 - Hs.98594]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_055444.2 ARHGEF10 gene product H. sapiens 100.0 1343
NP_766339.2 Arhgef10 gene product M. musculus 86.2 1344
XP_002665240.2 PREDICTED: rho guanine nucleotide exchange factor 10 D. rerio 68.9 1233
NP_788924.2 CG43658, isoform B D. melanogaster 48.8 215
Other hits (2 of 31) [Show all]SpeciesId(%)Len(aa)
XP_003902425.1 PREDICTED: rho guanine nucleotide exchange factor 10 isoform 1 P. anubis 98.9 1344
XP_002805294.1 PREDICTED: rho guanine nucleotide exchange factor 10-like M. mulatta 98.0 1047

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; embryonic tissue; eye; pharynx; thymus; placenta; cervix; uncharacterized tissue; pancreas; uterus; mixed; lung; kidney; mammary gland; larynx; ascites; connective tissue; ovary; heart; nerve; ganglia; bone; prostate; intestine; liver; skin; ear; salivary gland; muscle; trachea; adrenal gland; epididymis
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 8
Map position: 8p23
UniSTS entry: Chr 8 WI-11694 [Map Viewer]
UniSTS entry: Chr 8 AF009214
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

BC047307.1 Homo sapiens, clone IMAGE:5103002, mRNA A
AL137508.1 Homo sapiens mRNA; cDNA DKFZp761P221 (from clone DKFZp761P221) PA
NM_014629.2 Homo sapiens Rho guanine nucleotide exchange factor (GEF) 10 (ARHGEF10), mRNA P
CR749570.1 Homo sapiens mRNA; cDNA DKFZp686H0726 (from clone DKFZp686H0726) PA
BC112926.1 Homo sapiens Rho guanine nucleotide exchange factor (GEF) 10, mRNA (cDNA clone MGC:131664 IMAGE:6500770), complete cds PA
AK309799.1 Homo sapiens cDNA, FLJ99840 P
BC026965.1 Homo sapiens Rho guanine nucleotide exchange factor (GEF) 10, mRNA (cDNA clone IMAGE:5103002) A
BC036809.1 Homo sapiens Rho guanine nucleotide exchange factor (GEF) 10, mRNA (cDNA clone IMAGE:5737598), complete cds PA
BC040474.1 Homo sapiens Rho guanine nucleotide exchange factor (GEF) 10, mRNA (cDNA clone IMAGE:4250879), complete cds PA
AB002292.2 Homo sapiens mRNA for KIAA0294 gene, partial cds P
AF009205.1 Homo sapiens clone L5 unknown mRNA, partial cds PA

EST sequences (281)

AA973436.1 Clone IMAGE:1569062 lung 3' read A
AA922940.1 Clone IMAGE:1457427 intestine 3' read A
AI023253.1 Clone IMAGE:1642138 testis 3' read A
AI073923.1 Clone IMAGE:1632309 mammary gland 3' read A
AI076488.1 Clone IMAGE:1676644 embryonic tissue 3' read A
AI080139.1 Clone IMAGE:1678542 mixed 3' read A
AI161009.1 Clone IMAGE:1705412 heart 3' read A
AI190222.1 Clone IMAGE:1732737 heart 3' read A
CB122542.1 Clone L10ChoCK0-16-D10 liver 5' read
CB132814.1 Clone L14ChoiCK0-7-B11 liver 5' read
AI200894.1 Clone IMAGE:1755173 testis 3' read A
AI309232.1 Clone IMAGE:1913653 intestine 3' read A
AI336430.1 Clone IMAGE:1951015 lung 3' read PA
R38456.1 Clone IMAGE:136916 placenta 5' read
AI348138.1 Clone IMAGE:1927069 intestine 3' read A
AI359482.1 Clone IMAGE:2010127 uncharacterized tissue 3' read A
AI360941.1 Clone IMAGE:2010813 brain 3' read A
AI367567.1 Clone IMAGE:1989746 uterus 3' read
AI453641.1 Clone IMAGE:2144501 mixed 3' read A
AI472308.1 Clone IMAGE:2148476 mixed 3' read A
AI583226.1 Clone IMAGE:2213563 lung 3' read A
AI611015.1 Clone IMAGE:2254038 prostate 3' read A
AI621242.1 Clone IMAGE:2237286 uncharacterized tissue 3' read A
AI659207.1 Clone IMAGE:2249881 prostate 3' read A
AI680591.1 Clone IMAGE:2322063 prostate 3' read A
AI803869.1 Clone IMAGE:2189914 uterus 3' read A
AL048550.1 Clone DKFZp586P1324 uterus P
AL046200.1 Clone DKFZp434D117 testis 5' read A
AL046475.1 Clone DKFZp434B128 testis 5' read
AI823963.1 Clone IMAGE:2403471 kidney 3' read A
AI825242.1 Clone IMAGE:2305857 uncharacterized tissue 3' read A
AI829030.1 Clone IMAGE:2402266 kidney 3' read A
AI910829.1 Clone IMAGE:2393254 intestine 3' read
AI914232.1 Clone IMAGE:2337380 lung 3' read A
AI916776.1 Clone IMAGE:2316211 kidney 3' read A
AI638222.1 Clone IMAGE:2239270 uncharacterized tissue 3' read A
AI640616.1 Clone IMAGE:2298242 kidney 3' read
AL042034.1 Clone DKFZp434H171 testis 5' read P
AL043515.1 Clone DKFZp434C0427 testis 3' read
AI867761.1 Clone IMAGE:2307923 uncharacterized tissue 3' read A
BX437595.2 Clone CS0CAP007YL05 thymus 3' read
BX437596.2 Clone CS0CAP007YL05 thymus 5' read
AI952702.1 Clone IMAGE:2549677 ovary 3' read A
AI954767.1 Clone IMAGE:2473042 uncharacterized tissue 3' read
BX447036.2 Clone CL0BB024ZE12 uncharacterized tissue 5' read P
CD514846.1 Clone IMAGE:30396053 brain 5' read P
CD516168.1 Clone IMAGE:30397567 brain 5' read
CD518496.1 Clone IMAGE:30396154 brain 5' read
AW022804.1 Clone IMAGE:2486264 ear 5' read A
BX488375.1 Clone DKFZp686M24269 muscle 5' read P
AW027806.1 Clone IMAGE:2530530 kidney 3' read A
AW137716.1 Clone IMAGE:2716724 mixed 3' read A
AW137967.1 Clone IMAGE:2717420 mixed 3' read A
AW189080.1 Clone IMAGE:2674889 uterus 3' read A
AI902599.1 mammary gland P
AW296844.1 Clone IMAGE:2728289 uncharacterized tissue 3' read A
AW340568.1 Clone IMAGE:2908073 mixed 3' read
AW374957.1 intestine P
CK004712.1 Clone IMAGE:30723085 brain 5' read
AW515725.1 Clone IMAGE:2916512 uncharacterized tissue 3' read A
AW593554.1 Clone IMAGE:2945977 uncharacterized tissue 3' read A
AW594315.1 Clone IMAGE:2949885 uncharacterized tissue 3' read A
AW769756.1 Clone IMAGE:3006390 kidney 3' read A
AW772049.1 Clone IMAGE:3032605 kidney 3' read A
CK904584.1 Clone IMAGE:5673533 pancreas 3' read A
CK904585.1 Clone IMAGE:5673533 pancreas 5' read A
AW873746.1 Clone IMAGE:3120813 adrenal gland 3' read A
AW898941.1 brain
H02771.1 Clone IMAGE:150884 placenta 5' read
CN278620.1 embryonic tissue 5' read
CN307764.1 embryonic tissue 5' read P
CN307765.1 embryonic tissue 5' read P
CN307766.1 embryonic tissue 5' read P
CN307767.1 embryonic tissue 5' read
CN307768.1 embryonic tissue 5' read P
CN307777.1 embryonic tissue 5' read P
CN307778.1 embryonic tissue 5' read
CN307779.1 embryonic tissue 5' read
CN307780.1 embryonic tissue 5' read
CN307781.1 embryonic tissue 5' read P
CN307775.1 embryonic tissue 5' read P
CN307769.1 embryonic tissue 5' read P
CN307770.1 embryonic tissue 5' read
CN307771.1 embryonic tissue 5' read P
CN307772.1 embryonic tissue 5' read P
CN307773.1 embryonic tissue 5' read P
CN307774.1 embryonic tissue 5' read P
CN307776.1 embryonic tissue 5' read P
CN358643.1 embryonic tissue 5' read P
AW971071.1 uncharacterized tissue A
CV030934.1 mixed 5' read P
BP348873.1 Clone SZR02212 brain 5' read
BE504606.1 Clone IMAGE:3209356 uncharacterized tissue 3' read A
CV807480.1 Clone IMAGE:7501660 embryonic tissue 5' read A
BE546776.1 Clone IMAGE:3458204 cervix 5' read
H44629.1 Clone IMAGE:187919 mammary gland 3' read
H46405.1 Clone IMAGE:187919 mammary gland 5' read
CX871313.1 Clone IMAGE:7485893 embryonic tissue 5' read
BE777768.1 Clone IMAGE:3866712 eye 5' read P
BE814863.1 mammary gland
BE885770.1 Clone IMAGE:3910292 uterus 5' read P
DN994743.1 Clone TC101451 brain 5' read P
DR005168.1 Clone TC118131 prostate 5' read P
BE937777.1 testis
BF034097.1 Clone IMAGE:3859979 ovary 5' read
BF093614.1 testis
AU120207.1 Clone HEMBB1000199 mixed 5' read
AU125128.1 Clone NT2RM4001079 testis 5' read P
AU125341.1 Clone NT2RM4001432 testis 5' read P
BF115328.1 Clone IMAGE:3562360 brain 3' read A
AU134444.1 Clone OVARC1001980 ovary 5' read P
BF344743.1 Clone IMAGE:4152862 brain 5' read P
BF327295.1 mammary gland
BF446554.1 Clone IMAGE:3705482 lung 3' read A
BF446893.1 Clone IMAGE:3578848 prostate 3' read A
AA722461.1 Clone IMAGE:409951 heart 3' read A
DA116869.1 Clone BRACE3036364 brain 5' read P
DA038335.1 Clone BGGI12000875 uncharacterized tissue 5' read P
DA236970.1 Clone BRAWH3033755 brain 5' read
BF677292.1 Clone IMAGE:4250879 prostate 5' read
DA237812.1 Clone BRAWH3034783 brain 5' read P
DA291859.1 Clone BRHIP2003562 brain 5' read P
DA330756.1 Clone BRHIP3028222 brain 5' read P
DA213468.1 Clone BRAWH3003228 brain 5' read P
DA207520.1 Clone BRAWH2014593 brain 5' read P
DA025412.1 Clone ASTRO2008342 brain 5' read P
DA182925.1 Clone BRAMY3000334 brain 5' read P
DA190760.1 Clone BRAMY3013325 brain 5' read P
DA106884.1 Clone BRACE3021398 brain 5' read P
DA302855.1 Clone BRHIP2018151 brain 5' read P
BF846764.1 lung
DA109357.1 Clone BRACE3025905 brain 5' read P
DA529713.1 Clone FEBRA2022501 brain 5' read P
DA387889.1 Clone BRTHA2023810 brain 5' read P
DA400495.1 Clone BRTHA3003451 brain 5' read P
AW300465.1 Clone IMAGE:2774507 kidney 3' read A
AW302582.1 Clone IMAGE:2827262 brain 3' read A
DA406892.1 Clone BRTHA3012313 brain 5' read P
H70930.1 Clone IMAGE:239172 pharynx 3' read A
H70935.1 Clone IMAGE:239171 pharynx 3' read A
H71016.1 Clone IMAGE:239172 pharynx 5' read
H71021.1 Clone IMAGE:239171 pharynx 5' read
BF057043.1 Clone IMAGE:3444374 uncharacterized tissue 3' read A
DA487147.1 Clone FCBBF2004970 brain 5' read P
AU146338.2 Clone HEMBB1000199 mixed 3' read A
AU148860.1 Clone NT2RM4001079 testis 3' read A
DA909259.1 Clone SKNSH2001740 brain 5' read P
BF436869.1 Clone IMAGE:3650717 prostate 3' read A
DB046555.1 Clone TESTI2035136 testis 5' read
DA787238.1 Clone OCBBF2024718 brain 5' read P
BF591063.1 Clone IMAGE:3319265 intestine 3' read A
DB080912.1 Clone TESTI4026691 testis 5' read P
DB342369.1 Clone THYMU1000498 thymus 3' read A
DB075202.1 Clone TESTI4019007 testis 5' read P
DB075500.1 Clone TESTI4019396 testis 5' read P
DB069115.1 Clone TESTI4011258 testis 5' read P
DB271626.1 Clone UTERU2033519 uterus 5' read P
DB108833.1 Clone THYMU2011328 thymus 5' read P
DB298963.1 Clone BRACE3010136 brain 3' read A
DB109435.1 Clone THYMU2012158 thymus 5' read P
DB305114.1 Clone BRAWH3016904 brain 3' read A
DB305747.1 Clone BRAWH3033755 brain 3' read A
DB077104.1 Clone TESTI4021617 testis 5' read P
DB090018.1 Clone TESTI4038790 testis 5' read P
DB090404.1 Clone TESTI4039356 testis 5' read P
DB123695.1 Clone THYMU2032829 thymus 5' read P
DB352874.1 Clone UTERU3016843 uterus 3' read A
DB196797.1 Clone TRACH2003567 trachea 5' read P
DB130335.1 Clone THYMU2040943 thymus 5' read P
DB281047.1 Clone UTERU3007887 uterus 5' read P
DB119857.1 Clone THYMU2027702 thymus 5' read P
DB126522.1 Clone THYMU2036267 thymus 5' read P
BF748513.1 mammary gland
DB061291.1 Clone TESTI4001113 testis 5' read P
DB362999.1 Clone NT2RM4001432 testis 3' read A
DB127989.1 Clone THYMU2038048 thymus 5' read P
DB239531.1 Clone TRACH3035781 trachea 5' read P
DB101177.1 Clone THYMU1000498 thymus 5' read P
DB062675.1 Clone TESTI4002910 testis 5' read P
DB102031.1 Clone THYMU2001038 thymus 5' read P
DB129099.1 Clone THYMU2039398 thymus 5' read P
DB129228.1 Clone THYMU2039557 thymus 5' read P
DB102812.1 Clone THYMU2002209 thymus 5' read P
DB175185.1 Clone TKIDN2011364 kidney 5' read P
DB175191.1 Clone TKIDN2011372 kidney 5' read P
DB287796.1 Clone UTERU3016843 uterus 5' read
DB326941.1 Clone OCBBF3005101 brain 3' read
DB209786.1 Clone TRACH2022845 trachea 5' read
DB150374.1 Clone THYMU3026960 thymus 5' read P
DB111197.1 Clone THYMU2014654 thymus 5' read P
DB105043.1 Clone THYMU2005596 thymus 5' read P
DB105633.1 Clone THYMU2006495 thymus 5' read P
DB289318.1 Clone UTERU3018907 uterus 5' read P
BF773371.1 epididymis
DW413490.1 liver
DW422360.1 liver P
DW427975.1 liver
BF844516.1 larynx
BG180144.1 Clone IMAGE:4431127 prostate 5' read
DB518407.1 Clone H013059J17 testis 3' read A
DB442270.1 Clone H013003G19 testis 5' read
DB448701.1 Clone H013038A11 testis 5' read
EB385334.1 Clone nbj01c07 brain 5' read P
DB452942.1 Clone H013059J17 testis 5' read P
DB513840.1 Clone H013038A11 testis 3' read A
BG483302.1 Clone IMAGE:4617497 lung 5' read P
N46249.1 Clone IMAGE:279113 brain 5' read
N46250.1 Clone IMAGE:279113 brain 3' read A
DT220869.1 brain
BG536818.1 Clone IMAGE:4691125 lung 5' read
N50349.1 Clone IMAGE:280421 brain 5' read
N51571.1 Clone IMAGE:280421 brain 3' read A
N53385.1 Clone IMAGE:284022 brain 3' read A
BG760476.1 Clone IMAGE:4840274 skin 5' read
EL736658.1 mixed 5' read P
BG984236.1 intestine P
ES314255.1 skin 5' read
BI753125.1 Clone IMAGE:5196355 brain 5' read P
BM054717.1 Clone IMAGE:5673533 pancreas 3' read A
BM068727.1 Clone IMAGE:5673533 pancreas 5' read A
BM564667.1 Clone IMAGE:5737598 intestine 5' read
BM688690.1 Clone UI-E-CQ1-acq-g-04-0-UI brain 5' read
BM706495.1 Clone UI-E-CR1-ady-e-12-0-UI eye 5' read
BM707183.1 Clone UI-E-CR1-aea-g-04-0-UI eye 5' read
BM827861.1 Clone S11SNU1-45-H04 ascites 5' read
BM921957.1 Clone IMAGE:5753571 mixed 5' read P
BM978210.1 Clone UI-CF-EC1-aeb-b-17-0-UI lung 3' read A
AL702654.1 Clone DKFZp686O0815 muscle 5' read P
AL704004.1 Clone DKFZp686I0528 muscle 5' read P
BQ002527.1 Clone IMAGE:5844590 connective tissue 3' read A
BQ003951.1 Clone IMAGE:5848131 connective tissue 3' read A
BQ008629.1 Clone IMAGE:5840017 connective tissue 3' read A
BQ008902.1 Clone IMAGE:5840574 connective tissue 3' read A
BQ018422.1 Clone IMAGE:5893030 connective tissue 3' read A
W95331.1 Clone IMAGE:357689 heart 5' read
W95332.1 Clone IMAGE:357689 heart 3' read A
BQ231258.1 Clone IMAGE:6095725 skin 5' read P
BQ309332.1 mammary gland
BQ309393.1 mammary gland
BQ425267.1 Clone IMAGE:6156030 uterus 5' read P
BQ447674.1 Clone UI-H-EU1-baf-f-09-0-UI connective tissue 3' read A
BQ670124.1 Clone IMAGE:6213597 salivary gland 5' read
BQ719438.1 Clone IMAGE:6188074 nerve 5' read P
BF930007.1 brain P
BG119526.1 Clone IMAGE:4442261 liver 5' read P
BQ882509.1 Clone IMAGE:6181512 ganglia 5' read P
BQ889114.1 Clone IMAGE:6183602 ganglia 5' read P
BQ945920.1 Clone IMAGE:6470148 uterus 5' read A
BU178611.1 Clone IMAGE:6171253 eye 5' read P
BU193584.1 Clone IMAGE:6161028 skin 5' read P
BU506905.1 Clone IMAGE:6500770 uterus 5' read P
BU508773.1 Clone IMAGE:6503233 uterus 5' read P
BU153547.1 Clone IMAGE:6012541 uncharacterized tissue 5' read P
BU618148.1 Clone UI-H-FH1-bfe-a-04-0-UI bone 3' read A
BU618608.1 Clone UI-H-FH1-bfk-i-10-0-UI bone 3' read A
BU630774.1 Clone UI-H-FL0-bds-a-16-0-UI bone 3' read PA
BU616522.1 Clone UI-H-DF0-bey-n-21-0-UI bone 3' read A
BU626387.1 Clone UI-H-DF0-beu-m-14-0-UI bone 3' read A
BU727063.1 Clone UI-E-CQ1-acq-g-04-0-UI brain 3' read A
BU741995.1 Clone UI-E-EO1-aja-j-20-0-UI eye 3' read A
BU754567.1 Clone UI-1-BB1-aid-a-05-0-UI placenta 3' read A
HY005691.1 Clone H04D020B01 testis P
HY032444.1 Clone H04D112D13 testis P
CA390972.1 Clone cs116f11 eye 5' read P
CA423120.1 Clone UI-H-FE1-bdz-b-12-0-UI bone 3' read A
CA427009.1 Clone UI-H-DF0-bem-d-24-0-UI bone 3' read A
CA427713.1 Clone UI-H-DF0-bes-k-11-0-UI bone 3' read A
CA427910.1 Clone UI-H-DF0-bep-a-16-0-UI bone 3' read A
CA434016.1 Clone UI-H-DF0-arr-d-13-0-UI bone 3' read A
CA434024.1 Clone UI-H-DF0-arr-f-23-0-UI bone 3' read A
CA439175.1 Clone UI-H-DI0-auv-i-05-0-UI lung 3' read A
CA443097.1 Clone UI-H-DH1-awo-c-01-0-UI connective tissue 3' read A
AA400480.1 Clone IMAGE:742799 testis 3' read P
AA400454.1 Clone IMAGE:742799 testis 5' read P
F20190.2 Clone NOTAVAIL04359 muscle
AA507675.1 Clone IMAGE:941858 prostate
AA507684.1 Clone IMAGE:941857 prostate
AA507869.1 Clone IMAGE:942059 prostate
AA758332.1 Clone 1320523 testis 3' read A
R10884.1 Clone IMAGE:129126 mixed 3' read A
R10934.1 Clone IMAGE:129126 mixed 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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