> Natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) (NPR2)
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UGID:140224     UniGene Hs.78518     Homo sapiens (human)   NPR2
Natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) (NPR2)

Human protein-coding gene NPR2. Represented by 134 ESTs from 74 cDNA libraries. Corresponds to reference sequence NM_003995.3. [UniGene 140224 - Hs.78518]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003911569.1 PREDICTED: atrial natriuretic peptide receptor 2 P. anubis 100.0 1046
NP_003986.2 NPR2 gene product H. sapiens 100.0 1046
XP_001085221.1 PREDICTED: atrial natriuretic peptide receptor 2 isoform 2 M. mulatta 99.9 1046
XP_001168194.1 PREDICTED: atrial natriuretic peptide receptor 2 isoform 2 P. troglodytes 99.9 1046
NP_776149.1 Npr2 gene product M. musculus 99.1 1046
NP_001084176.1 natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) X. laevis 84.7 1019
NP_001038402.1 atrial natriuretic peptide receptor 1 precursor D. rerio 73.3 1017
NP_650505.2 CG31183 D. melanogaster 65.1 682
NP_491380.1 Protein GCY-28, isoform b C. elegans 64.5 498
XP_001697314.1 guanylate cyclase C. reinhardtii 51.9 188
Other hits (2 of 38) [Show all]SpeciesId(%)Len(aa)
XP_001504537.1 PREDICTED: atrial natriuretic peptide receptor 2 E. caballus 99.3 1046
NP_446290.1 Npr2 gene product R. norvegicus 99.2 1046

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; eye; ovary; prostate; thyroid; uterus; adipose tissue; skin; ear; testis; mammary gland; liver; kidney; intestine; adrenal gland; larynx; heart; connective tissue; pancreas; umbilical cord; bone; lung; pituitary gland; uncharacterized tissue; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 9
Map position: 9p21-p12
UniSTS entry: Npr2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (3)

NM_003995.3 Homo sapiens natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) (NPR2), mRNA PA
BC023017.1 Homo sapiens natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B), mRNA (cDNA clone IMAGE:4939622), partial cds PA
L13436.1 Homo sapiens guanylate cyclase mRNA, complete mature peptide P

EST sequences (134)

AA994689.1 Clone IMAGE:1632011 mammary gland 3' read PA
R19620.1 Clone IMAGE:34645 brain 5' read
AI051689.1 Clone IMAGE:1673788 mixed 3' read
AI090222.1 Clone IMAGE:1697078 uterus 3' read P
AI199042.1 Clone IMAGE:1859506 brain 3' read
AI274470.1 Clone IMAGE:1986056 uterus 3' read
AI288159.1 Clone IMAGE:1986989 uterus 3' read
AI433910.1 Clone IMAGE:2130789 kidney 3' read P
R51752.1 Clone IMAGE:38928 brain 5' read P
R51753.1 Clone IMAGE:38928 brain 3' read A
R54629.1 Clone IMAGE:154521 mammary gland 3' read
R54636.1 Clone IMAGE:154836 mammary gland 3' read
R54893.1 Clone IMAGE:154521 mammary gland 5' read P
AI653862.1 Clone IMAGE:2277905 uterus 3' read P
R44407.1 Clone IMAGE:34645 brain 3' read
AI587508.1 Clone IMAGE:2221857 pancreas 3' read PA
AI672965.1 Clone IMAGE:2346851 intestine 3' read
AI675662.1 Clone IMAGE:2321089 prostate 3' read P
R55442.1 Clone IMAGE:154968 mammary gland 5' read
AI684178.1 Clone IMAGE:2267536 uterus 3' read P
AI686545.1 Clone IMAGE:2268562 uterus 3' read
AI695246.1 Clone IMAGE:2296878 kidney 3' read A
AI702776.1 Clone IMAGE:2340386 lung 3' read
AI768998.1 Clone IMAGE:2366705 mixed 3' read P
AI784653.1 Clone IMAGE:2042994 uterus 3' read
AI799095.1 Clone IMAGE:2349153 mixed 3' read P
AI804800.1 Clone IMAGE:2268082 uterus 3' read
AI804819.1 Clone IMAGE:2268075 uterus 3' read
AL039986.1 Clone DKFZp434L2012 testis 5' read
CB269692.1 adipose tissue 5' read P
AI925370.1 Clone IMAGE:2449157 lung 3' read P
AI934871.1 Clone IMAGE:2469538 brain 3' read
BX433213.1 Clone CS0DF034YJ22 brain 3' read
AI972940.1 Clone IMAGE:2490664 prostate 3' read P
AW001125.1 Clone IMAGE:2520989 intestine 3' read PA
CD513723.1 Clone IMAGE:30393488 pituitary gland 5' read P
AW009073.1 Clone IMAGE:2503845 intestine 3' read
AW021883.1 Clone IMAGE:2484958 ear 5' read
AL119417.1 Clone DKFZp761J111 brain 5' read P
AL120802.1 Clone DKFZp762E172 skin 5' read PA
AW051383.1 Clone IMAGE:2555288 mixed 3' read P
AW118990.1 Clone IMAGE:2604679 mixed 3' read P
AI114487.1 liver P
F07784.1 Clone c-2hf02 brain P
F04038.1 Clone c-2hf02 brain 3' read
AW172274.1 Clone IMAGE:2659335 mixed 3' read
AW172859.1 Clone IMAGE:2656282 uterus 3' read P
AL133931.1 Clone DKFZp761O0714 brain 5' read P
F12779.1 Clone c-3ed03 brain P
F10387.1 Clone c-3ed03 brain 3' read
AW373106.1 mammary gland
AW373117.1 mammary gland
AW384623.1 thyroid
AW384634.1 thyroid
AW444775.1 Clone IMAGE:2733228 uncharacterized tissue 3' read A
AW468745.1 Clone IMAGE:2910725 mixed 3' read P
AW513674.1 Clone IMAGE:2737850 intestine 3' read
AW959953.1 uncharacterized tissue P
CN841943.1 Clone IMAGE:7002022 mixed 5' read P
BP871636.1 Clone HKR00990 kidney 5' read P
CR745749.1 Clone IMAGp998M074883_;_IMAGE:1986990 uterus 3' read A
CR740687.1 Clone IMAGp998J154173_;_IMAGE:1644782 testis 5' read
AV649932.2 Clone GLCBZC02 liver 3' read
BE834110.1 ovary
AV695041.2 Clone GKCAGF12 liver 5' read
BE881748.1 Clone IMAGE:3892363 lung 5' read P
DR006407.1 Clone TC117646 intestine 5' read P
R94585.1 Clone IMAGE:276280 mixed 5' read P
R94586.1 Clone IMAGE:276280 mixed 3' read
AV747335.1 Clone NPCCWH04 pituitary gland 5' read
AV750469.1 Clone NPCARF09 pituitary gland 5' read
T28606.1 brain 5' read P
BF112084.1 Clone IMAGE:3523862 mixed 3' read P
BF112225.1 Clone IMAGE:3523982 mixed 3' read P
BF438988.1 Clone IMAGE:3269771 mixed 3' read
BF569929.1 Clone IMAGE:4310130 kidney 5' read P
BF570413.1 Clone IMAGE:4310130 kidney 3' read P
H86537.1 Clone IMAGE:223307 eye 3' read
H86623.1 Clone IMAGE:223307 eye 5' read
BF825925.1 larynx P
BF844062.1 thyroid P
BF969116.1 Clone IMAGE:4358036 adrenal gland 5' read P
BF961582.1 brain
BG167086.1 Clone IMAGE:4454731 kidney 5' read PA
DB540090.1 Clone H023051F15 brain 3' read PA
BG911225.1 Clone IMAGE:4939622 brain 5' read P
BI045583.1 prostate P
BI045632.1 prostate P
BI754833.1 Clone IMAGE:5195686 brain 5' read P
BM677353.1 Clone UI-E-EO1-aic-l-24-0-UI eye 3' read A
BM678122.1 Clone UI-E-EJ0-aif-a-11-0-UI eye 3' read PA
BM680695.1 Clone UI-E-EO1-ajc-b-15-0-UI eye 3' read PA
BM682796.1 Clone UI-E-EJ1-ajf-i-24-0-UI eye 3' read PA
BM683362.1 Clone UI-E-EJ1-aje-k-04-0-UI eye 3' read PA
BM718802.1 Clone UI-E-EO1-ajc-b-15-0-UI eye 5' read P
BM719471.1 Clone UI-E-EJ1-ajf-i-24-0-UI eye 5' read P
BM721771.1 Clone UI-E-EO1-aic-l-24-0-UI eye 5' read P
BM725486.1 Clone UI-E-EJ0-aif-a-11-0-UI eye 5' read P
W67706.1 Clone IMAGE:343297 heart 5' read P
W68165.1 Clone IMAGE:343297 heart 3' read
W68319.1 Clone IMAGE:342692 heart 3' read
BQ006433.1 Clone IMAGE:5845965 connective tissue 3' read A
BQ015978.1 Clone IMAGE:5886533 connective tissue 3' read PA
BQ180956.1 Clone IMAGE:5851808 connective tissue 3' read PA
BQ184647.1 Clone UI-E-EJ1-ajr-n-01-0-UI eye 3' read PA
BQ186623.1 Clone UI-E-EJ1-ajr-n-01-0-UI eye 5' read P
AA004366.1 Clone IMAGE:428369 mixed 5' read
AA004367.1 Clone IMAGE:428369 mixed 3' read A
BQ446138.1 Clone UI-H-EU1-baa-c-05-0-UI connective tissue 3' read PA
BQ771511.1 Clone UI-H-EZ1-bbf-i-14-0-UI bone 3' read A
BM929411.1 Clone UI-E-EJ1-aje-k-04-0-UI eye 5' read A
BU076981.1 Clone IMAGE: pancreas 3' read
BU077323.1 Clone IMAGE: pancreas 5' read
AA136039.1 Clone IMAGE:490138 uterus 3' read
AA136201.1 Clone IMAGE:490138 uterus 5' read P
AA187473.1 Clone IMAGE:625567 umbilical cord 5' read P
AA187648.1 Clone IMAGE:625567 umbilical cord 3' read
BU957197.1 Clone IMAGE:6731187 mammary gland 5' read P
CA397959.1 Clone cs98b05 eye 3' read PA
CA397960.1 Clone cs98b05 eye 5' read P
T75207.1 Clone IMAGE:22841 brain 5' read P
CA423152.1 Clone UI-H-FE1-bdz-h-06-0-UI bone 3' read PA
CA424770.1 Clone UI-H-FE1-bdx-h-22-0-UI bone 3' read PA
CA427137.1 Clone UI-H-DF0-bex-o-15-0-UI bone 3' read PA
CA429143.1 Clone UI-H-FH1-bfh-m-20-0-UI bone 3' read PA
AA314498.1 intestine 5' read P
AA361824.1 uncharacterized tissue 5' read P
AA365501.1 pineal gland 5' read P
T88750.1 Clone IMAGE:115492 mixed 5' read
AA565715.1 Clone IMAGE:993354 adrenal gland 3' read
AA565716.1 Clone IMAGE:993356 adrenal gland 3' read
AA700814.1 Clone IMAGE:436078 mixed 3' read P
AA702979.1 Clone IMAGE:447178 mixed 3' read
AA704545.1 Clone IMAGE:451138 mixed 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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