> Fumarylacetoacetate hydrolase (fumarylacetoacetase) (FAH)
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UGID:139604     UniGene Hs.73875     Homo sapiens (human)   FAH Order cDNA clone, Links
Fumarylacetoacetate hydrolase (fumarylacetoacetase) (FAH)

Human protein-coding gene FAH. Represented by 312 ESTs from 154 cDNA libraries. Corresponds to reference sequence NM_000137.2. [UniGene 139604 - Hs.73875]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000128.1 FAH gene product H. sapiens 100.0 418
XP_001155533.3 PREDICTED: fumarylacetoacetase isoform 3 P. troglodytes 99.8 420
NP_034306.2 Fah gene product M. musculus 91.9 418
NP_955895.1 fah gene product D. rerio 80.1 346
NP_001080458.1 fumarylacetoacetase X. laevis 79.2 419
NP_509083.1 Protein FAH-1 C. elegans 69.3 414
NP_524830.2 fumarylacetoacetase D. melanogaster 68.5 412
NP_172669.2 fumarylacetoacetase A. thaliana 63.4 418
XP_001701519.1 predicted protein C. reinhardtii 57.6 425
XP_960499.1 fumarylacetoacetase N. crassa 56.4 427
Other hits (2 of 50) [Show all]SpeciesId(%)Len(aa)
XP_001109382.1 PREDICTED: fumarylacetoacetase isoform 1 M. mulatta 97.6 418
XP_003901338.1 PREDICTED: fumarylacetoacetase P. anubis 97.6 418

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: pancreas; lymph; pharynx; mouth; salivary gland; thyroid; connective tissue; blood; eye; lung; testis; ovary; kidney; uncharacterized tissue; brain; skin; cervix; liver; mixed; placenta; esophagus; spleen; mammary gland; prostate; heart; adipose tissue; uterus; intestine; muscle; embryonic tissue; lymph node; stomach; ganglia; bone; pituitary gland; adrenal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q25.1
UniSTS entry: RH13
UniSTS entry: GDB:369113
UniSTS entry: Chr 15 RH136637
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

BT007160.1 Homo sapiens fumarylacetoacetate hydrolase (fumarylacetoacetase) mRNA, complete cds P
NM_000137.2 Homo sapiens fumarylacetoacetate hydrolase (fumarylacetoacetase) (FAH), mRNA PA
M55150.1 Human fumarylacetoacetate hydrolase mRNA, complete cds P
BC002527.1 Homo sapiens fumarylacetoacetate hydrolase (fumarylacetoacetase), mRNA (cDNA clone MGC:1557 IMAGE:3139988), complete cds PA
AK313951.1 Homo sapiens cDNA, FLJ94596, Homo sapiens fumarylacetoacetate hydrolase (fumarylacetoacetase)(FAH), mRNA P
X51728.1 Human mRNA for fumarylacetoacetase (EC 3.7.1.2) P
S63549.1 fumaryl acetoacetate hydrolase {alternatively spliced S product} [human, mRNA Partial Mutant, 117 nt]
S63548.1 fumaryl acetoacetate hydrolase {alternatively spliced L product} [human, mRNA Partial Mutant, 324 nt]

EST sequences (312)

AA969802.1 Clone IMAGE:1572718 kidney 3' read PA
AA946814.1 Clone IMAGE:1589100 kidney 3' read PA
BX113482.1 Clone IMAGp998A11264_;_IMAGE:162706 mammary gland P
BX117399.1 Clone IMAGp998B165997 brain 5' read A
AI207324.1 Clone IMAGE:1762157 kidney 3' read PA
CB164152.1 Clone L17N670205n1-36-E09 liver 5' read P
CB123338.1 Clone L13SNU387-3-B07 liver 5' read P
CB149777.1 Clone L15CKK1-47-B06 liver 5' read P
AI197878.1 Clone IMAGE:1860157 brain 3' read
AI273103.1 Clone IMAGE:1986297 uterus 3' read A
AI300664.1 Clone IMAGE:1909232 lung 3' read A
AI347512.1 Clone IMAGE:2063108 intestine 3' read A
AI431855.1 Clone IMAGE:2131568 kidney 3' read PA
AI434352.1 Clone IMAGE:2133696 lymph node 3' read A
AI473317.1 Clone IMAGE:2125271 mixed 3' read A
AI473732.1 Clone IMAGE:2137085 kidney 3' read A
AI400031.1 Clone IMAGE:2115572 mixed 3' read A
AI623631.1 Clone IMAGE:2229316 pancreas 3' read PA
AI597683.1 Clone IMAGE:2254577 prostate 3' read PA
AI634024.1 Clone IMAGE:2299835 kidney 3' read P
AI652755.1 Clone IMAGE:2310249 uncharacterized tissue 3' read A
AI655725.1 Clone IMAGE:2240788 uncharacterized tissue 3' read P
AI657020.1 Clone IMAGE:2244085 uncharacterized tissue 3' read P
AI659260.1 Clone IMAGE:2251399 prostate 3' read
F34188.1 Clone s3000064E01 muscle PA
AI671961.1 Clone IMAGE:2316808 kidney 3' read PA
AI721274.1 Clone IMAGE:2335261 intestine 3' read P
AI738545.1 Clone IMAGE:2392050 intestine 3' read P
AL048038.2 Clone DKFZp586E0823 uterus P
AL048039.1 Clone DKFZp586E0823 uterus A
AI817717.1 Clone IMAGE:2413359 brain 3' read A
BX346413.2 Clone CS0DL009YO12 uncharacterized tissue 3' read P
BX346414.2 Clone CS0DL009YO12 uncharacterized tissue 5' read P
BX376761.2 Clone CS0DD005YG01 uncharacterized tissue 5' read P
CD108550.1 Clone IMAGE:30364670 pituitary gland 5' read P
BX329587.2 Clone CS0DC013YI22 uncharacterized tissue 3' read P
BX353953.2 Clone CS0DC013YI22 uncharacterized tissue 5' read P
BX351394.2 Clone CS0DI011YA05 placenta 3' read A
BX364749.2 Clone CS0DI011YA05 placenta 3' read P
BX385863.2 Clone CS0DI011YA05 placenta 5' read P
BX381525.2 Clone CS0DI066YL10 placenta 3' read P
BX381526.2 Clone CS0DI066YL10 placenta 5' read P
BX396058.2 Clone CS0DI011YA05 placenta 5' read P
BX341251.2 Clone CS0DJ013YP24 blood 5' read P
BX330922.2 Clone CS0DJ013YP24 blood 3' read PA
AI950361.1 Clone IMAGE:2464407 kidney 3' read PA
BX405116.2 Clone CS0DH001YG11 blood 5' read
BX444514.2 Clone CS0DN003YD21 brain 5' read P
BX411514.2 Clone CS0DN003YD21 brain 3' read
AI970254.1 Clone IMAGE:2479299 uncharacterized tissue 3' read PA
CD369851.1 Clone UI-H-FT1-bke-g-13-0-UI lung 3' read PA
AW006854.1 Clone IMAGE:2497247 kidney 3' read PA
BX474390.1 Clone DKFZp686H22169 muscle 5' read
AW025998.1 Clone IMAGE:2528649 kidney 3' read A
CD673836.1 Clone fs05b06 eye 5' read P
CD699577.1 pharynx P
AW078966.1 Clone IMAGE:2576875 kidney 3' read A
CF130306.1 Clone IMAGE:30559448 lung 5' read PA
CF126929.1 Clone IMAGE:30563484 lung 5' read P
AW194886.1 Clone IMAGE:2696587 kidney 3' read PA
BP429848.1 Clone LEU1852_27_C12 P
AW206951.1 Clone IMAGE:2723078 mixed 3' read PA
AW328180.1 Clone IMAGE:2847185 lymph 5' read P
AW328181.1 Clone IMAGE:2847185 lymph 3' read PA
AW444672.1 Clone IMAGE:2733438 uncharacterized tissue 3' read PA
AW594679.1 Clone IMAGE:2950922 uncharacterized tissue 3' read
AW675064.1 Clone IMAGE:2900997 placenta 5' read P
AW732915.1 Clone IMAGE:2963109 placenta 5' read P
AW904058.1 brain
AW950492.1 uncharacterized tissue P
CN278438.1 embryonic tissue 5' read P
BE045550.1 Clone IMAGE:2955962 lung 3' read PA
BE046351.1 Clone IMAGE:3026648 intestine 3' read PA
BE076562.1 mammary gland P
BE222148.1 Clone IMAGE:3165969 lung 3' read P
CV029215.1 mixed 5' read P
BE270488.1 Clone IMAGE:3543294 lymph 5' read P
BE276702.1 Clone IMAGE:3050080 skin 5' read P
BP242962.1 Clone HEP18327 liver 5' read P
BE277563.1 Clone IMAGE:3050957 skin 5' read P
BP296402.1 Clone MPC00891 uncharacterized tissue 5' read P
BP305160.1 Clone MPG03703 uncharacterized tissue 5' read P
BE281065.1 Clone IMAGE:3139988 placenta 5' read P
BP317420.1 Clone PCD03661 heart 5' read P
BP353608.1 Clone T7R01683 esophagus 5' read P
BP331947.1 Clone REC00848 kidney 5' read P
H25257.1 Clone IMAGE:161180 mammary gland 3' read
BP340208.1 Clone SPL08331 spleen 5' read P
BP259476.1 Clone HRT06876 heart 5' read P
BP265910.1 Clone JTH02258 thyroid 5' read P
BP276400.1 Clone KDN06289 kidney 5' read P
BE326748.1 Clone IMAGE:3133262 kidney 3' read PA
BP381646.1 Clone adKA03359 adipose tissue 5' read P
H26104.1 Clone IMAGE:161131 mammary gland 3' read
H27535.1 Clone IMAGE:162706 mammary gland 3' read A
H27604.1 Clone IMAGE:162706 mammary gland 5' read
BE465622.1 Clone IMAGE:3171860 skin 3' read P
BE514002.1 Clone IMAGE:3634694 lymph 5' read P
BE539182.1 Clone IMAGE:3451311 placenta 5' read
BE540143.1 Clone IMAGE:3447739 placenta 5' read P
BE545414.1 Clone IMAGE:3459266 cervix 5' read P
CX164724.1 Clone IMAGE:7467992 embryonic tissue 5' read P
AV652849.1 Clone GLCDEG04 liver 3' read P
AV653576.1 Clone GLCDMD02 liver 3' read P
H44956.1 Clone IMAGE:183200 mammary gland 3' read
BE707463.1 thyroid
BE731501.1 Clone IMAGE:3843438 placenta 5' read P
BE731646.1 Clone IMAGE:3841806 placenta 5' read P
BE735387.1 Clone IMAGE:3639244 pancreas 5' read P
BE787159.1 Clone IMAGE:3879463 lung 5' read P
AV685112.1 Clone GKCECD05 liver 5' read P
AV685114.1 Clone GKCECD07 liver 5' read P
AV686093.1 Clone GKCEDA12 liver 5' read P
AV695285.1 Clone GKCFVD04 liver 5' read P
AV696309.1 Clone GKCFJG11 liver 5' read
AV699455.1 Clone GKCEDB12 liver 3' read PA
AV700094.1 Clone GKCECA12 liver 3' read P
DN996252.1 Clone TC120070 mammary gland 5' read P
BE971288.1 Clone IMAGE:3935110 muscle 5' read P
BF001255.1 Clone IMAGE:3314319 intestine 3' read
DR159021.1 Clone IMAGE:7968127 embryonic tissue 5' read P
AV735979.1 Clone CBLAOF12 blood 5' read A
AU126645.2 Clone NT2RP1001349 testis 5' read P
BF116102.1 Clone IMAGE:3570547 ovary 3' read PA
BF196323.1 Clone IMAGE:3569714 ovary 3' read P
T29301.1 brain 5' read
BF316821.1 Clone IMAGE:4135734 brain 5' read P
H57100.1 Clone IMAGE:204767 mixed 5' read
DA085975.1 Clone BRACE2040493 brain 5' read P
BF688407.1 Clone IMAGE:4299574 eye 5' read P
BF688882.1 Clone IMAGE:4299574 eye 3' read P
H67318.1 Clone IMAGE:229638 mixed 5' read
H68527.1 Clone IMAGE:229638 mixed 3' read A
DA139672.1 Clone BRALZ2014005 brain 5' read P
BF727056.1 Clone by16b09 eye 5' read P
DA687722.1 Clone NT2NE2006312 5' read P
DA401725.1 Clone BRTHA3005189 brain 5' read P
AW301168.1 Clone IMAGE:2773734 kidney 3' read PA
DA402659.1 Clone BRTHA3006503 brain 5' read P
DA912367.1 Clone SKNSH2006131 brain 5' read P
BF573232.1 Clone IMAGE:4254147 skin 5' read P
DB243486.1 Clone TSTOM2002118 stomach 5' read
BF830418.1 mouth P
BF982992.1 Clone IMAGE:4399539 intestine 5' read P
BF977626.1 Clone IMAGE:4306372 skin 5' read
BG178311.1 Clone IMAGE:4431878 prostate 5' read P
DB576810.1 Clone H033095J20 brain 3' read PA
DB505531.1 Clone H033095J20 brain 5' read P
BG248794.1 Clone IMAGE:4546434 intestine 5' read P
EB362109.1 Clone ki23a09 eye
AL521927.3 Clone CS0DB007YF24 uncharacterized tissue 5' read P
AL527761.3 Clone CS0DC026YP24 uncharacterized tissue 5' read P
AL558508.3 Clone CS0DJ006YC20 blood 5' read P
AL562973.3 Clone CS0DC026YP24 uncharacterized tissue 3' read P
AL580312.3 Clone CS0DJ006YC20 blood 3' read P
BG281443.1 Clone IMAGE:4544151 skin 5' read P
BG331590.1 Clone IMAGE:4550947 lung 5' read P
BG332217.1 Clone IMAGE:4551395 lung 5' read P
BG431115.1 Clone IMAGE:4612138 kidney 5' read P
BG477285.1 Clone IMAGE:4641777 skin 5' read P
BG480261.1 Clone IMAGE:4653910 placenta 5' read P
BG491713.1 Clone IMAGE:4654192 skin 5' read P
BG492281.1 Clone IMAGE:4654192 skin 3' read P
BG492912.1 Clone IMAGE:4655580 salivary gland 5' read P
BG497292.1 Clone IMAGE:4659300 salivary gland 5' read P
BG500752.1 Clone IMAGE:4669337 prostate 5' read P
AU099797.1 Clone KAT03992 uncharacterized tissue 5' read
BG540323.1 Clone IMAGE:4693493 lung 5' read P
BG565367.1 Clone IMAGE:4711371 liver 5' read PA
BG566541.1 Clone IMAGE:4714409 liver 5' read P
BG574984.1 Clone IMAGE:4706611 mammary gland 5' read P
BG183607.1 connective tissue A
BG184119.1 connective tissue
BG188847.1 connective tissue A
BG190488.1 connective tissue
BG193025.1 connective tissue A
BG193026.1 connective tissue A
BG207429.1 connective tissue A
BG209026.1 connective tissue
BG211103.1 connective tissue
BG216990.1 connective tissue A
BG219035.1 connective tissue A
BG674250.1 Clone IMAGE:4746026 skin 5' read P
BG744095.1 Clone IMAGE:4849315 blood 5' read P
BG744760.1 Clone IMAGE:4849315 blood 3' read P
BG750217.1 Clone IMAGE:4845722 eye 5' read P
BG763885.1 Clone IMAGE:4862434 skin 5' read P
BG764021.1 Clone IMAGE:4862405 skin 5' read P
BG767488.1 Clone IMAGE:4871377 skin 5' read P
BG768404.1 Clone IMAGE:4871845 skin 5' read
BG769620.1 Clone IMAGE:4877791 skin 5' read P
BI090083.1 Clone IMAGE:4998599 placenta 5' read P
N75464.1 Clone IMAGE:299150 lung 3' read A
BI009150.1 kidney
N79231.1 Clone IMAGE:292390 mixed 5' read PA
BJ995334.1 Clone hmft-2252 liver 5' read P
BJ995335.1 Clone hmft-2252 liver 3' read P
BI226664.1 Clone IMAGE:5095796 lymph 5' read P
AL598665.1 Clone DKFZp313N0721 uncharacterized tissue 5' read
DC361845.1 Clone KIDNE2008873 kidney 5' read P
DC357909.1 Clone HHDPC2006472 skin 5' read P
BI522754.1 Clone IMAGE:5240071 brain 5' read P
BI771177.1 Clone IMAGE:5204253 mixed 5' read P
BI826132.1 Clone IMAGE:5168874 brain 5' read P
BI828275.1 Clone IMAGE:5169905 brain 5' read P
BI908526.1 Clone IMAGE:5219064 blood 5' read P
BM008973.1 Clone IMAGE:5423105 pancreas 5' read P
BM009026.1 Clone IMAGE:5423102 pancreas 5' read P
W05273.1 Clone IMAGE:299150 lung 5' read P
BM044073.1 Clone IMAGE:5446667 prostate 5' read P
BM046789.1 Clone IMAGE:5455618 prostate 5' read
BM172121.1 Clone IMAGE:4735152 lung 5' read P
BM126301.1 Clone IMAGE:5675602 pancreas 5' read P
BM126571.1 Clone IMAGE:5675779 pancreas 5' read P
BM553265.1 Clone IMAGE:5467138 skin 5' read P
W56168.1 Clone IMAGE:339245 pancreas 5' read
W60478.1 Clone IMAGE:339245 pancreas 3' read A
W68774.1 Clone IMAGE:342625 heart 5' read
BM905803.1 Clone IMAGE:5556160 uterus 5' read P
BM914795.1 Clone IMAGE:5480506 skin 5' read P
BM917521.1 Clone IMAGE:5484050 blood 5' read P
BM923519.1 Clone IMAGE:5759188 mixed 5' read P
BM924112.1 Clone IMAGE:5760319 mixed 5' read P
BM924814.1 Clone IMAGE:5761268 mixed 5' read P
W79322.1 Clone IMAGE:346959 heart 5' read
W79422.1 Clone IMAGE:346959 heart 3' read A
W94120.1 Clone IMAGE:357626 heart 3' read PA
W94165.1 Clone IMAGE:357626 heart 5' read
BQ051581.1 Clone IMAGE:5932503 blood 5' read P
BQ051854.1 Clone IMAGE:5932877 blood 5' read P
BQ051988.1 Clone IMAGE:5933074 blood 5' read P
BQ051996.1 Clone IMAGE:5933085 blood 5' read P
BQ052148.1 Clone IMAGE:5933309 blood 5' read P
BQ052266.1 Clone IMAGE:5933487 blood 5' read P
BQ052387.1 Clone IMAGE:5933663 blood 5' read P
BQ053719.1 Clone IMAGE:5935586 blood 5' read P
BQ054252.1 Clone IMAGE:5936319 blood 5' read P
BQ058174.1 Clone IMAGE:5813984 lymph 5' read P
BQ223430.1 Clone IMAGE:6058897 lung 5' read P
BQ225295.1 Clone IMAGE:6025061 pancreas 5' read P
BQ229474.1 Clone IMAGE:6057018 lung 5' read P
BQ331655.1 lung P
BQ332037.1 lung P
BQ332124.1 lung P
BQ332287.1 lung P
BQ332472.1 lung P
BQ332493.1 lung P
BQ332510.1 lung P
BQ332515.1 lung P
BQ332519.1 lung
BQ642488.1 Clone IMAGE:6303508 lymph 5' read P
BQ673561.1 Clone IMAGE:6254965 salivary gland 5' read P
BQ718801.1 Clone IMAGE:6184237 ganglia 5' read P
BF923221.1 brain
BG122956.1 Clone IMAGE:4443682 liver 5' read P
BQ920009.1 Clone IMAGE:6481593 prostate 5' read P
BQ920715.1 Clone IMAGE:6482793 prostate 5' read P
BU170440.1 Clone IMAGE:6139405 eye 5' read P
BU178854.1 Clone IMAGE:6167636 skin 5' read P
BU521861.1 Clone IMAGE:6527761 uterus 5' read P
BU157177.1 Clone IMAGE:6071684 skin 5' read P
BU157749.1 Clone IMAGE:6253850 skin 5' read P
BU527013.1 Clone IMAGE:6536754 lung 5' read P
AA101493.1 Clone IMAGE:563970 testis 5' read
AA101494.1 Clone IMAGE:563970 testis 3' read A
T61052.1 Clone IMAGE:76999 ovary 3' read
C03290.1 Clone 3NHC1227 heart P
FN166450.1 Clone 279319_1522_2630
FN142104.1 Clone 224961_1613_1716
FN124366.1 Clone 182154_2544_1226
BU624024.1 Clone UI-H-FG1-bgh-j-08-0-UI bone 3' read PA
BU630046.1 Clone UI-H-FL0-bdr-h-09-0-UI bone 3' read PA
BU657171.1 Clone cl21a09 blood 5' read P
BU679766.1 Clone UI-CF-EC1-abk-h-23-0-UI lung 3' read A
BU734913.1 Clone UI-E-DW0-agi-i-16-0-UI eye 3' read PA
BU856741.1 Clone IMAGE:6646503 mammary gland 5' read P
BU955820.1 Clone IMAGE:6729270 mammary gland 5' read P
BU956000.1 Clone IMAGE:6729474 mammary gland 5' read P
HY013719.1 Clone H04D047J07 testis P
HY020137.1 Clone H04D068D17 testis P
HY032105.1 Clone H04D111B17 testis P
HY044070.1 Clone H04D154O09 testis P
HY197942.1 Clone H04D047J07 testis P
HY216635.1 Clone H04D111B17 testis P
HY220482.1 Clone H04D122K02 testis
HY226527.1 Clone H04D141H10 testis PA
HY226875.1 Clone H04D142H10 testis PA
HY230367.1 Clone H04D154O09 testis P
T74849.1 Clone IMAGE:84962 liver 5' read
CA407235.1 adipose tissue 5' read
CA453567.1 Clone IMAGE:6717537 mixed 5' read P
AA331647.1 embryonic tissue 5' read P
AA336658.1 uterus 5' read
AA336741.1 uterus 5' read P
AA337115.1 uterus 5' read P
AA337366.1 uterus 5' read
T77808.1 Clone IMAGE:108813 mixed 5' read P
T77809.1 Clone IMAGE:108813 mixed 3' read
AA404416.1 Clone IMAGE:772239 embryonic tissue 3' read PA
AA404460.1 Clone IMAGE:772239 embryonic tissue 5' read
T83741.1 Clone IMAGE:113328 mixed 3' read A
T83912.1 Clone IMAGE:113328 mixed 5' read P
AA452208.1 Clone IMAGE:788004 embryonic tissue 5' read P
AA534626.1 Clone IMAGE:925611 intestine 3' read P
AA534645.1 Clone IMAGE:925635 intestine 3' read P
AA555140.1 Clone IMAGE:1029643 prostate A
AA555264.1 Clone IMAGE:1029729 prostate PA
AA600971.1 Clone IMAGE:993786 adrenal gland 3' read P
AA627252.1 Clone IMAGE:1157474 mammary gland 3' read A
AA652439.1 Clone IMAGE:1188070 prostate 3' read
R06364.1 Clone IMAGE:126236 mixed 5' read
AA777102.1 Clone IMAGE:377889 heart 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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