> Myelin protein zero (MPZ)
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UGID:2060497     UniGene Hs.591486     Homo sapiens (human)   MPZ Links
Myelin protein zero (MPZ)

Human protein-coding gene MPZ. Represented by 120 ESTs from 35 cDNA libraries. EST representation biased toward nerve; juvenile. Corresponds to reference sequence NM_000530.6. [UniGene 2060497 - Hs.591486]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000521.2 MPZ gene product H. sapiens 100.0 247
XP_001173975.1 PREDICTED: myelin protein P0 P. troglodytes 99.6 257
XP_001118030.1 PREDICTED: myelin protein P0-like M. mulatta 99.6 255
NP_032649.2 Mpz gene product M. musculus 96.4 247
NP_001091356.1 myelin protein P0 precursor X. laevis 65.1 237
NP_919342.1 mpz gene product D. rerio 53.7 202
Other hits (2 of 14) [Show all]SpeciesId(%)Len(aa)
XP_003893018.1 PREDICTED: myelin protein P0 P. anubis 98.4 255
XP_001925038.2 PREDICTED: myelin protein P0-like S. scrofa 98.4 246

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: nerve [show more like this]
juvenile [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; ganglia; nerve; thymus; skin; lymph node; uncharacterized tissue; embryonic tissue; mixed; testis; intestine; heart; muscle; prostate; blood; trachea; lung; ear; eye; pituitary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q23.3
UniSTS entry: Chr 1 GDB:453314
UniSTS entry: Chr 1 G15925
UniSTS entry: Chr 1 GDB:453316
UniSTS entry: Chr 1 GDB:567273
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

BT006765.1 Homo sapiens myelin protein zero (Charcot-Marie-Tooth neuropathy 1B) mRNA, complete cds P
NM_000530.6 Homo sapiens myelin protein zero (MPZ), mRNA PA
AK313555.1 Homo sapiens cDNA, FLJ94116, Homo sapiens myelin protein zero (Charcot-Marie-Tooth neuropathy1B) (MPZ), mRNA P
S66705.1 P0=28 kda major peripheral myelin protein [human, Charcot-Marie-Tooth disease type 1B patient, mRNA PartialMutant, 385 nt] P
D10537.1 Homo sapiens mRNA for major structural protein of myelin, complete cds P

EST sequences (120)

AI005369.1 Clone IMAGE:1624878 embryonic tissue 3' read A
BX090441.1 Clone IMAGp998M074121_;_IMAGE:1624878 embryonic tissue A
AI351956.1 Clone IMAGE:1933324 mixed 3' read A
BX354427.2 Clone CS0DC019YC04 uncharacterized tissue 5' read P
BX370296.2 Clone CS0DJ005YB08 blood 5' read
CD172001.1 Clone IMAGE:30375727 brain 5' read P
CD172093.1 Clone IMAGE:30377441 brain 5' read P
CD172164.1 Clone IMAGE:30375814 brain 5' read
CD172268.1 Clone IMAGE:30376004 brain 5' read
CD172418.1 Clone IMAGE:30377382 brain 5' read
CD245143.1 Clone IMAGE:30376311 brain 5' read P
CD245600.1 Clone IMAGE:30376899 brain 5' read P
CD245675.1 Clone IMAGE:30374113 brain 5' read P
CD245726.1 Clone IMAGE:30376918 brain 5' read P
CD245786.1 Clone IMAGE:30375501 brain 5' read P
CD300650.1 Clone IMAGE:30386657 testis 5' read P
CD300752.1 Clone IMAGE:30375482 brain 5' read P
CD514180.1 Clone IMAGE:30397088 brain 5' read
CD514580.1 Clone IMAGE:30395694 brain 5' read P
CD514837.1 Clone IMAGE:30396071 brain 5' read
CD514980.1 Clone IMAGE:30408769 brain 5' read P
CD514993.1 Clone IMAGE:30408695 brain 5' read P
CD515313.1 Clone IMAGE:30408013 brain 5' read P
CD515400.1 Clone IMAGE:30394953 brain 5' read
CD515605.1 Clone IMAGE:30408218 brain 5' read P
CD515776.1 Clone IMAGE:30395094 brain 5' read P
CD515823.1 Clone IMAGE:30394868 brain 5' read P
CD515923.1 Clone IMAGE:30400150 brain 5' read
CD516182.1 Clone IMAGE:30395180 brain 5' read P
CD516632.1 Clone IMAGE:30408127 brain 5' read P
CD516663.1 Clone IMAGE:30407987 brain 5' read
CD516787.1 Clone IMAGE:30397783 brain 5' read P
CD516933.1 Clone IMAGE:30408206 brain 5' read
CD517230.1 Clone IMAGE:30399197 brain 5' read P
CD517321.1 Clone IMAGE:30397916 brain 5' read P
CD517340.1 Clone IMAGE:30397850 brain 5' read P
CD518426.1 Clone IMAGE:30399929 brain 5' read
CD518464.1 Clone IMAGE:30396292 brain 5' read P
CD518611.1 Clone IMAGE:30398280 brain 5' read
CD519170.1 Clone IMAGE:30399949 brain 5' read
CD519505.1 Clone IMAGE:30398744 brain 5' read P
CD519678.1 Clone IMAGE:30407694 brain 5' read P
CD556707.1 Clone IMAGE:30393609 pituitary gland 5' read P
CD558285.1 Clone IMAGE:30395727 brain 5' read P
CD558543.1 Clone IMAGE:30396767 brain 5' read
CD558570.1 Clone IMAGE:30396651 brain 5' read P
CD558968.1 Clone IMAGE:30399949 brain 5' read
AW183708.1 Clone IMAGE:2664159 mixed 3' read A
CF457260.1 Clone IMAGE:30514204 nerve 5' read
BE243817.1 Clone TCBAP1595 lymph node
CV026776.1 mixed 5' read P
CR743243.1 Clone IMAGp998L074636_;_IMAGE:1892118 uncharacterized tissue 5' read
BP222912.1 Clone COR05250 skin 5' read P
BP367206.1 Clone TMS03442 thymus 5' read
BE677387.1 Clone IMAGE:3279832 ganglia 3' read A
BE677712.1 Clone IMAGE:3280277 ganglia 3' read A
BE729420.1 Clone IMAGE:3831300 skin 5' read P
BE729566.1 Clone IMAGE:3926008 skin 5' read P
DA346091.1 Clone BRSSN2007029 brain 5' read P
DA346277.1 Clone BRSSN2007285 brain 5' read P
DA346292.1 Clone BRSSN2007305 brain 5' read P
DA341289.1 Clone BRSSN2000565 brain 5' read P
DA146177.1 Clone BRAMY2002861 brain 5' read P
DA342931.1 Clone BRSSN2002849 brain 5' read P
DA076630.1 Clone BRACE2028780 brain 5' read P
DA344252.1 Clone BRSSN2004605 brain 5' read P
DA353425.1 Clone BRSSN2017059 brain 5' read P
DA426167.1 Clone COLON2001350 intestine 5' read P
DA354919.1 Clone BRSSN2019052 brain 5' read P
DA560692.1 Clone HEART2001561 heart 5' read P
DA559602.1 Clone HEART2000041 heart 5' read P
DA820320.1 Clone PERIC2000020 heart 5' read P
DA895339.1 Clone SKMUS2002867 muscle 5' read P
BF476769.1 Clone IMAGE:4091575 nerve 3' read A
BF509916.1 Clone IMAGE:3087337 uncharacterized tissue 3' read A
DA873427.1 Clone PROST2010671 prostate 5' read P
DB210759.1 Clone TRACH2024041 trachea 5' read P
BF941221.1 Clone IMAGE:3280529 ganglia 3' read A
BG149262.1 Clone IMAGE:3366573 lung 3' read A
EB388714.1 Clone nbj49d03 brain 5' read P
AL527658.3 Clone CS0DC026YB11 uncharacterized tissue 3' read
AL527659.3 Clone CS0DC026YB11 uncharacterized tissue 5' read P
BG330626.1 Clone IMAGE:4547957 lung 5' read
BI492423.1 Clone IMAGE:2484003 ear 3' read A
BI493499.1 Clone IMAGE:2540918 ear 3' read
BM663255.1 Clone UI-E-CI0-aai-b-02-0-UI eye 3' read A
BM690416.1 Clone UI-E-CI0-aai-b-02-0-UI eye 5' read
BM926188.1 Clone IMAGE:5764561 brain 5' read
BQ716449.1 Clone IMAGE:6196378 nerve 5' read P
BQ717175.1 Clone IMAGE:6189523 nerve 5' read P
BQ717695.1 Clone IMAGE:6189023 nerve 5' read P
BQ718137.1 Clone IMAGE:6189506 nerve 5' read
BQ718867.1 Clone IMAGE:6186905 nerve 5' read
BQ718902.1 Clone IMAGE:6187141 nerve 5' read P
BQ718978.1 Clone IMAGE:6189742 nerve 5' read
BQ719047.1 Clone IMAGE:6189412 nerve 5' read P
BQ719539.1 Clone IMAGE:6188153 nerve 5' read
BQ719976.1 Clone IMAGE:6190060 nerve 5' read
BQ720015.1 Clone IMAGE:6190931 nerve 5' read P
BQ723057.1 Clone IMAGE:6189939 nerve 5' read P
BG057517.1 Clone IMAGE:3303335 ganglia 3' read A
BQ876808.1 Clone IMAGE:6192259 nerve 5' read P
BQ879340.1 Clone IMAGE:6177452 ganglia 5' read P
BQ879736.1 Clone IMAGE:6182697 ganglia 5' read P
BQ882169.1 Clone IMAGE:6180859 ganglia 5' read P
BQ889135.1 Clone IMAGE:6185580 ganglia 5' read P
BQ889407.1 Clone IMAGE:6182482 ganglia 5' read
BQ889715.1 Clone IMAGE:6180056 ganglia 5' read P
BQ893587.1 Clone IMAGE:6182426 ganglia 5' read P
BQ897587.1 Clone IMAGE:6185494 ganglia 5' read P
BQ897743.1 Clone IMAGE:6181231 ganglia 5' read P
BQ898128.1 Clone IMAGE:6177625 ganglia 5' read P
BQ898550.1 Clone IMAGE:6182160 ganglia 5' read P
BQ942129.1 Clone IMAGE:6204114 nerve 5' read P
BQ951864.1 Clone IMAGE:6201155 nerve 5' read P
BU146445.1 Clone IMAGE:6182573 ganglia 5' read P
BU146866.1 Clone IMAGE:6186159 ganglia 5' read P
BU838381.1 Clone IMAGE:6176977 ganglia 5' read P
BU838551.1 Clone IMAGE:6177237 ganglia 5' read P
AA602431.1 Clone IMAGE:1114679 prostate


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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