> Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 (MLLT3)
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UGID:2060096     UniGene Hs.591085     Homo sapiens (human)   MLLT3
Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 (MLLT3)

Human protein-coding gene MLLT3. Represented by 202 ESTs from 108 cDNA libraries. Corresponds to reference sequence NM_004529.2. [UniGene 2060096 - Hs.591085]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001108646.2 PREDICTED: protein AF-9 isoform 2 M. mulatta 100.0 608
NP_004520.2 MLLT3 gene product H. sapiens 100.0 567
XP_001148491.1 PREDICTED: protein AF-9 P. troglodytes 100.0 566
XP_003911721.1 PREDICTED: protein AF-9 P. anubis 100.0 506
NP_081602.3 Mllt3 gene product M. musculus 99.3 568
NP_001017819.1 mllt3 gene product D. rerio 78.7 554
NP_001087981.1 uncharacterized protein LOC494666 X. laevis 63.4 551
NP_651979.1 ENL/AF9-related, isoform A D. melanogaster 50.3 169
Other hits (2 of 30) [Show all]SpeciesId(%)Len(aa)
NP_001179478.1 protein AF-9 B. taurus 99.5 566
XP_002708121.1 PREDICTED: myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 O. cuniculus 99.3 568

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; pharynx; mammary gland; intestine; bladder; bone marrow; testis; embryonic tissue; ovary; kidney; uncharacterized tissue; muscle; uterus; spleen; prostate; trachea; blood; skin; ear; pancreas; liver; connective tissue; adrenal gland; eye; ascites; bone; heart; mouth; lung; stomach
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 9
Map position: 9p22
UniSTS entry: Chr 9 GDB:373748
UniSTS entry: Chr 9 BE111905
UniSTS entry: Chr 9 D9S1886
UniSTS entry: Chr 9 RH11443 [Map Viewer]
UniSTS entry: Chr 1 D1S1425
UniSTS entry: Chr 1 D11S2560
UniSTS entry: Chr 9 MLLT3__6320
UniSTS entry: Chr 1 GDB:434012
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

BX649194.1 Homo sapiens mRNA; cDNA DKFZp686D09204 (from clone DKFZp686D09204) PA
AK128222.1 Homo sapiens cDNA FLJ46355 fis, clone TESTI4049110
NM_004529.2 Homo sapiens myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 (MLLT3), mRNA P
L13744.1 Human AF-9 mRNA, complete cds P
AK225957.1 Homo sapiens mRNA for myeloid/lymphoid or mixed-lineage leukemia variant, clone: FCC114E07 P
EF406122.1 Homo sapiens MLL/AF9 translocation breakpoint junction sequence
AK312914.1 Homo sapiens cDNA, FLJ93363, highly similar to Homo sapiens myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 (MLLT3), mRNA P
BC030550.1 Homo sapiens myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3, mRNA (cDNA clone IMAGE:5212069), containing frame-shift errors PA
AK301474.1 Homo sapiens cDNA FLJ53222 complete cds, highly similar to Protein AF-9 P
AK297587.1 Homo sapiens cDNA FLJ58676 complete cds, highly similar to Protein AF-9 P
D16688.1 Homo sapiens mRNA for LTG9/MLLT3 protein, partial cds P
BC036089.1 Homo sapiens myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3, mRNA (cDNA clone MGC:33789 IMAGE:5298142), complete cds PA

EST sequences (202)

AI093669.1 Clone IMAGE:1688352 mixed 3' read A
BX095046.1 Clone IMAGp998F08274_;_IMAGE:46936 brain A
CB142289.1 Clone L11SNU354s1-21-E12 liver 5' read P
AI336478.1 Clone IMAGE:1913009 intestine 3' read P
AI375975.1 Clone IMAGE:2066091 embryonic tissue 3' read A
AI479335.1 Clone IMAGE:2157806 mixed 3' read A
AI554049.1 Clone IMAGE:2090040 mixed 3' read A
AI620408.1 Clone IMAGE:2258752 stomach 3' read A
AF063504.1 Clone HA0056 uncharacterized tissue PA
AI739108.1 Clone IMAGE:2390573 intestine 3' read
AI742296.1 Clone IMAGE:2368514 mixed 3' read P
AI768397.1 Clone IMAGE:2371843 mixed 3' read A
AL045208.1 Clone DKFZp434F1950 testis 5' read P
AI911245.1 Clone IMAGE:2366900 mixed 3' read
CB999623.1 Clone IMAGE:30323795 mixed 5' read
BX332070.2 Clone CS0DC007YC10 uncharacterized tissue 5' read
BX372645.2 Clone CS0DC007YC10 uncharacterized tissue 3' read
BX420503.2 Clone CS0DF029YH24 brain 5' read P
BX452207.2 Clone CS0DF029YH24 brain 5' read P
BX505582.1 Clone DKFZp686F24203 muscle 5' read P
AW044133.1 Clone IMAGE:2553892 mixed 3' read A
AW044186.1 Clone IMAGE:2553975 mixed 3' read A
CD686525.1 pharynx
AW157750.1 Clone IMAGE:2783137 brain 3' read P
AW163788.1 Clone IMAGE:2783137 brain 5' read P
AI110630.1 liver PA
F11547.1 Clone c-2yd07 brain P
F09208.1 Clone c-2yd07 brain 3' read A
CF597021.1 Clone IMAGE:30704754 ovary 5' read P
AW364802.1 kidney
AW572468.1 Clone IMAGE:2806541 kidney 3' read A
AW949446.1 uncharacterized tissue
CN284867.1 embryonic tissue 5' read P
CN284868.1 embryonic tissue 5' read P
CN284869.1 embryonic tissue 5' read P
CN284870.1 embryonic tissue 5' read P
H10052.1 Clone IMAGE:46936 brain 3' read A
H10106.1 Clone IMAGE:46936 brain 5' read P
BE091105.1 mammary gland
H18503.1 Clone IMAGE:171855 brain 3' read A
H19168.1 Clone IMAGE:171855 brain 5' read P
CV024688.1 mixed 5' read P
BP229185.1 Clone FBR02339 brain 5' read P
BP229778.1 Clone FBR04529 brain 5' read P
BP248356.1 Clone HKR10825 kidney 5' read P
BP214451.1 Clone CCR00822 brain 5' read P
BP315061.1 Clone OFR07722 mammary gland 5' read P
BP329045.1 Clone RCT02347 intestine 5' read P
BP359831.1 Clone THR00192 brain 5' read P
BP257735.1 Clone HRT01742 heart 5' read
BP279346.1 Clone KGR04848 brain 5' read P
BP290552.2 Clone LNF05548 lung 5' read P
BP311216.1 Clone NRR05364 brain 5' read P
BP347393.1 Clone SZB04628 brain 5' read P
BP376873.1 Clone WMC05560 uterus 5' read P
BP377465.1 Clone WMC07644 uterus 5' read P
BE697838.1 intestine
BE697888.1 intestine
R83091.1 Clone IMAGE:194454 mixed 5' read P
DN997592.1 Clone TC117322 mammary gland 5' read P
BF029498.1 Clone IMAGE:3997583 bladder 5' read P
R98334.1 Clone IMAGE:201619 mixed 5' read P
T28209.1 embryonic tissue 5' read
BF104863.1 Clone IMAGE:4045485 kidney 5' read P
AV755398.2 Clone BMFAGF12 bone marrow 5' read
AV756536.2 Clone BMFAYD08 bone marrow 5' read A
CR983169.1 Clone RZPDp9017L2025 uncharacterized tissue 5' read P
DR760267.1 Clone IMAGE:7969536 embryonic tissue 5' read P
BF243978.1 Clone IMAGE:4105124 bone marrow 5' read
DN915508.1 Clone MCF7_RNA_L_20_D23 mammary gland
DN915509.1 Clone MCF7_RNA_L_20_D23 mammary gland P
DN916404.1 Clone MCF7_RNA_L_21_K24 mammary gland
DN916405.1 Clone MCF7_RNA_L_21_K24 mammary gland P
DA179427.1 Clone BRAMY2043847 brain 5' read P
DA154985.1 Clone BRAMY2013823 brain 5' read P
DA496194.1 Clone FCBBF3008970 brain 5' read P
DA499093.1 Clone FCBBF3012672 brain 5' read P
DA361527.1 Clone BRSTN2007908 brain 5' read P
DA427944.1 Clone COLON2003543 intestine 5' read P
DA506764.1 Clone FCBBF3022640 brain 5' read P
AW302520.1 Clone IMAGE:2827142 brain 3' read
DA507666.1 Clone FCBBF3023758 brain 5' read P
DA631796.1 Clone KIDNE2013262 kidney 5' read P
DA560926.1 Clone HEART2001875 heart 5' read P
DA600279.1 Clone HSYRA2005321 connective tissue 5' read P
DA483902.1 Clone FCBBF2000374 brain 5' read P
DA589342.1 Clone HLUNG2010979 lung 5' read
DA446955.1 Clone CTONG2018157 mouth 5' read P
AV723679.1 Clone HTBAPF09 brain 5' read
DA525337.1 Clone FEBRA2016807 brain 5' read P
DA525963.1 Clone FEBRA2017606 brain 5' read P
DA493252.1 Clone FCBBF3005185 brain 5' read P
DA533069.1 Clone FEBRA2026883 brain 5' read P
DA488197.1 Clone FCBBF2006510 brain 5' read P
DA501080.1 Clone FCBBF3015215 brain 5' read
DA797639.1 Clone OCBBF3000797 brain 5' read P
DB041861.1 Clone TESTI2029046 testis 5' read P
DA780103.1 Clone OCBBF2015203 brain 5' read P
DA780893.1 Clone OCBBF2016257 brain 5' read P
BF434955.1 Clone IMAGE:3642422 kidney 3' read
DA784570.1 Clone OCBBF2020968 brain 5' read P
DA902131.1 Clone SKNMC2001979 brain 5' read P
DA785612.1 Clone OCBBF2022371 brain 5' read P
DA793034.1 Clone OCBBF2032815 brain 5' read P
DA793964.1 Clone OCBBF2034167 brain 5' read P
DA939436.1 Clone SPLEN2013003 spleen 5' read P
BF510928.1 Clone IMAGE:3088258 uncharacterized tissue 3' read P
DA880396.1 Clone PROST2019810 prostate 5' read P
BF791449.1 Clone IMAGE:4343995 adrenal gland 5' read
DA796988.1 Clone OCBBF3000005 brain 5' read
DB267301.1 Clone UTERU2027428 uterus 5' read P
DB349461.1 Clone TRACH3012930 trachea 3' read
DW430048.1 liver P
DW450947.1 liver
DW461871.1 liver
BF969793.1 Clone IMAGE:4360353 adrenal gland 5' read P
BF940546.1 Clone IMAGE:3436270 ovary 3' read
H99306.1 Clone IMAGE:260349 skin 3' read A
DB465529.1 Clone H023017D04 brain 5' read
DB446428.1 Clone H013025D05 testis 5' read P
EB385927.1 Clone nbj09e01 brain 5' read P
DB511587.1 Clone H013025D05 testis 3' read A
AL535503.3 Clone CS0DF010YC09 brain 5' read P
EC465881.1 prostate
EC494594.1 prostate
EC494752.1 prostate
EC525830.1 prostate
EC538392.1 prostate
BG574623.1 Clone IMAGE:4705564 mammary gland 5' read P
N56884.1 Clone IMAGE:277479 brain 3' read
N66033.1 Clone IMAGE:293913 mixed 3' read A
BG958583.1 intestine
BG940264.1 Clone ax04e08 blood P
BG940265.1 Clone ax04e08 blood A
DC296184.1 Clone SYNOV4003903 connective tissue 5' read P
DC296538.1 Clone SYNOV4008237 connective tissue 5' read P
DC374421.1 Clone OCBBF2006454 brain 5' read P
DC366359.1 Clone NT2NE2013103 5' read P
DC374439.1 Clone OCBBF2006702 brain 5' read P
DC349852.1 Clone FCBBF2003903 brain 5' read P
DC352153.1 Clone FCBBF3028150 brain 5' read
DC350133.1 Clone FCBBF2007719 brain 5' read P
DC376033.1 Clone OCBBF2028905 brain 5' read P
DC350362.1 Clone FCBBF3002982 brain 5' read P
DC426027.1 Clone FCBBF3013748 brain 3' read
DC374922.1 Clone OCBBF2012912 brain 5' read P
DC374942.1 Clone OCBBF2013159 brain 5' read P
DC376490.1 Clone OCBBF2036126 brain 5' read P
DC377806.1 Clone OCBBF3024807 brain 5' read P
DC377922.1 Clone OCBBF3026425 brain 5' read P
DC375325.1 Clone OCBBF2018439 brain 5' read P
DC350559.1 Clone FCBBF3005771 brain 5' read P
DC350585.1 Clone FCBBF3006228 brain 5' read P
DC375691.1 Clone OCBBF2023415 brain 5' read P
DC350906.1 Clone FCBBF3010450 brain 5' read P
DC353445.1 Clone FEBRA2017949 brain 5' read P
DC351144.1 Clone FCBBF3013748 brain 5' read
DC315590.1 Clone BRAMY2032279 brain 5' read P
DC351254.1 Clone FCBBF3015343 brain 5' read P
DC351266.1 Clone FCBBF3015483 brain 5' read P
DC351276.1 Clone FCBBF3015570 brain 5' read P
DC296131.1 Clone SYNOV4003251 connective tissue 5' read P
BI497072.1 Clone IMAGE:2537590 ear 5' read A
BI550359.1 Clone IMAGE:5263584 brain 5' read P
BI561777.1 Clone IMAGE:5298142 testis 5' read
BI710808.1 Clone IMAGE:5023066 pancreas 5' read P
BI711138.1 Clone IMAGE:5023066 pancreas 3' read PA
N95149.1 Clone IMAGE:293913 mixed 5' read
BI857131.1 Clone IMAGE:5392661 mammary gland 5' read P
BM018568.1 Clone IMAGE:5427892 brain 5' read P
BM310961.1 pancreas 5' read
BM664793.1 Clone UI-E-CL1-afd-i-20-0-UI eye 3' read A
BM692521.1 Clone UI-E-CL1-afd-h-10-0-UI eye 5' read
BM703320.1 Clone UI-E-CL1-afd-i-20-0-UI eye 5' read
BM722291.1 Clone UI-E-EO0-ahx-a-02-0-UI eye 5' read
BM793722.1 Clone S22SNU16n1-26-D08 ascites 5' read P
BM853218.1 Clone S22SNU16n1-134-G11 ascites 5' read
AA002249.1 Clone IMAGE:427747 mixed 3' read A
BQ439638.1 Clone IMAGE:6062108 skin 5' read P
BG058267.1 Clone IMAGE:4231934 pharynx 5' read
FN056606.1 Clone 014469_2757_4038
BU579666.1 Clone IMAGE:6122296 pancreas 3' read A
BU623899.1 Clone UI-H-FG1-bgh-m-12-0-UI bone 3' read PA
BU622359.1 Clone UI-H-FL1-bfz-a-05-0-UI bone 3' read PA
BU633484.1 Clone UI-H-FL1-bgu-j-06-0-UI bone 3' read A
BU616826.1 Clone UI-H-FH1-bfj-a-20-0-UI bone 3' read P
BU664780.1 Clone cl122e05 blood 5' read P
BU733026.1 Clone UI-E-CL1-afd-h-10-0-UI eye 3' read A
BU951432.1 Clone IMAGE:6126442 pancreas 3' read PA
BU951699.1 Clone IMAGE:6126442 pancreas 5' read
HY021674.1 Clone H04D073I08 testis
HY047148.1 Clone H04D165J09 testis
HY204858.1 Clone H04D073I08 testis P
HY233750.1 Clone H04D165J09 testis P
CA439243.1 Clone UI-H-DT1-awa-g-18-0-UI connective tissue 3' read A
AA406302.1 Clone IMAGE:754560 mixed 3' read A
AA421983.1 Clone IMAGE:754560 mixed 5' read P
AA442076.1 Clone IMAGE:774717 embryonic tissue 3' read
AA442179.1 Clone IMAGE:774717 embryonic tissue 5' read
AA443284.1 Clone IMAGE:783998 embryonic tissue 3' read A
AA523648.1 Clone IMAGE:981609 bone
AA621884.1 Clone IMAGE:1144752 intestine 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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