> Kelch-like family member 18 (KLHL18)
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UGID:908693     UniGene Hs.517946     Homo sapiens (human)   KLHL18 Order cDNA clone, Links
Kelch-like family member 18 (KLHL18)

Human protein-coding gene KLHL18. Represented by 212 ESTs from 123 cDNA libraries. Corresponds to reference sequence NM_025010.4. [UniGene 908693 - Hs.517946]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_079286.2 KLHL18 gene product H. sapiens 100.0 573
XP_003894557.1 PREDICTED: kelch-like protein 18 P. anubis 99.8 573
XP_001144888.2 PREDICTED: kelch-like protein 18 isoform 1 P. troglodytes 99.8 573
XP_001100798.2 PREDICTED: kelch-like protein 18-like M. mulatta 99.6 508
NP_808439.2 kelch-like 18 M. musculus 99.1 573
NP_001086780.1 kelch-like 18 X. laevis 91.2 570
NP_956124.1 klhl18 gene product D. rerio 87.1 565
NP_650143.1 KLHL18, isoform A D. melanogaster 57.0 570
NP_499785.2 Protein KEL-3, isoform a C. elegans 47.6 548
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
XP_003358466.2 PREDICTED: kelch-like protein 18-like, partial S. scrofa 98.9 90
XP_001077154.3 PREDICTED: kelch-like protein 18-like R. norvegicus 98.6 573

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; pancreas; placenta; mouth; embryonic tissue; thyroid; liver; adrenal gland; testis; uncharacterized tissue; uterus; mammary gland; intestine; muscle; mixed; eye; lymph node; blood; kidney; lung; bone marrow; trachea; thymus; cervix; skin; prostate; heart; spleen; bone; connective tissue; vascular; nerve; ascites
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 3
Map position: 3p21.31
UniSTS entry: Chr 3 RH113
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

AB018338.1 Homo sapiens mRNA for KIAA0795 protein, partial cds P
BX537953.1 Homo sapiens mRNA; cDNA DKFZp686M0586 (from clone DKFZp686M0586); complete cds PA
AK001337.1 Homo sapiens cDNA FLJ10475 fis, clone NT2RP2000088, highly similar to Homo sapiens mRNA for KIAA0795 protein
AY714879.1 Homo sapiens Kelch-like 18 (KLHL18) mRNA, complete cds, alternatively spliced P
AK023765.1 Homo sapiens cDNA FLJ13703 fis, clone PLACE2000246, weakly similar to RING CANAL PROTEIN P
NM_025010.4 Homo sapiens kelch-like family member 18 (KLHL18), mRNA PA
BC015962.1 Homo sapiens kelch-like 18 (Drosophila), mRNA (cDNA clone IMAGE:4081125), partial cds A
AK291477.1 Homo sapiens cDNA FLJ77309 complete cds, highly similar to Homo sapiens kelch-like 18 (Drosophila) (KLHL18), mRNA P
BC016388.2 Homo sapiens kelch-like 18 (Drosophila), mRNA (cDNA clone IMAGE:3344095), partial cds PA
AB062478.1 Homo sapiens OK/SW-cl.74 mRNA, complete cds PA
BC032620.1 Homo sapiens kelch-like 18 (Drosophila), mRNA (cDNA clone MGC:44941 IMAGE:5578173), complete cds PA
AK295292.1 Homo sapiens cDNA FLJ61265 complete cds, highly similar to Kelch-like protein 18 P

EST sequences (212)

R15199.1 Clone IMAGE:29489 brain 5' read
R15200.1 Clone IMAGE:29491 brain 5' read P
R20207.1 Clone IMAGE:34549 brain 5' read
AI147462.1 Clone IMAGE:1693964 heart 3' read A
BX101858.1 Clone IMAGp998N06273_;_IMAGE:46562 brain A
BX111026.1 Clone IMAGp998A022037_;_IMAGE:824329 lymph node
R36761.1 Clone IMAGE:33296 brain 5' read
AI356423.1 Clone IMAGE:2027544 uncharacterized tissue 3' read P
AI418729.1 Clone IMAGE:2106259 brain 3' read
AI418739.1 Clone IMAGE:2106284 brain 3' read
AI472958.1 Clone IMAGE:2147394 mixed 3' read
T08375.1 Clone HIBBD41 brain 5' read
AI557487.1 prostate 3' read
AI630602.1 Clone ad13a11 blood
AU280345.1 Clone N1ESE2001550 uncharacterized tissue 5' read P
CB240943.1 Clone UI-CF-FN0-afx-a-23-0-UI lung 3' read A
AI754328.1 Clone HBMSC_cr23e04 bone marrow 3' read A
AI767531.1 Clone IMAGE:2381999 kidney 3' read A
AI796206.1 Clone IMAGE:2383566 kidney 3' read A
AI867863.1 Clone IMAGE:2308059 uncharacterized tissue 3' read
Z38488.1 Clone c-0dd04 brain 3' read A
AW016724.1 Clone IMAGE:2711670 uncharacterized tissue 3' read A
BX472373.1 Clone DKFZp686M14132 muscle 5' read P
BX474564.1 Clone DKFZp686K08170 muscle 5' read P
BX481136.1 Clone DKFZp686M02224 muscle 5' read P
BX490931.1 Clone DKFZp686J0492 muscle 5' read P
BX491441.1 Clone DKFZp686F2498 muscle 5' read P
BX509893.1 Clone DKFZp686M0586 muscle 5' read P
AW083400.1 Clone IMAGE:2583126 intestine 3' read A
CF137066.1 Clone IMAGE:3090526 lymph node 5' read P
AW151264.1 Clone IMAGE:2630682 uterus 3' read A
AW188077.1 Clone IMAGE:2664670 mixed 3' read
BX642442.1 Clone DKFZp686M0586 muscle 3' read A
AW241674.1 Clone IMAGE:2704022 uterus 3' read A
AW292084.1 Clone IMAGE:2725543 uncharacterized tissue 3' read A
AW294275.1 Clone IMAGE:2726345 uncharacterized tissue 3' read A
AL138305.1 Clone DKFZp547L237 brain 5' read
AW370551.1 mammary gland
AW373097.1 mammary gland
AW380608.1 mouth
AW384614.1 thyroid
CK004934.1 Clone IMAGE:30722814 brain 5' read
AW500390.1 Clone IMAGE:3077094 lymph node 5' read P
AW504933.1 Clone IMAGE:3080933 lymph node 5' read
CD632380.1 uncharacterized tissue
CD632381.1 uncharacterized tissue
AW576579.1 Clone IMAGE:3080933 lymph node 3' read P
AW628969.1 Clone IMAGE:2975284 mixed 3' read
R77708.1 Clone IMAGE:143873 placenta 5' read
BX954898.1 Clone DKFZp781G0759 uncharacterized tissue 5' read P
CK820159.1 Clone IMAGE:5678236 pancreas 5' read A
CK820158.1 Clone IMAGE:5678236 pancreas 3' read
AW876748.1 uncharacterized tissue P
AW966663.1 uncharacterized tissue
D20030.1 Clone pm1758 blood 3' read
D20471.1 Clone pm2832 blood 3' read
H09758.1 Clone IMAGE:46562 brain 3' read A
H09842.1 Clone IMAGE:46562 brain 5' read
H10248.1 Clone IMAGE:46801 brain 5' read P
H10446.1 Clone IMAGE:47194 brain 5' read
H10447.1 Clone IMAGE:47194 brain 3' read
BE170147.1 thyroid
BE258722.1 Clone IMAGE:3344095 eye 5' read P
CV030864.1 mixed 5' read P
BP357587.1 Clone TDR03545 mammary gland 5' read P
BP284218.1 Clone KMR08441 bone marrow 5' read P
BP271124.1 Clone KAR06488 intestine 5' read P
CV814910.1 Clone IMAGE:7500763 embryonic tissue 5' read P
AV653097.1 Clone GLCDHD01 liver 3' read
H42760.1 Clone IMAGE:183354 mammary gland 5' read
H42761.1 Clone IMAGE:183354 mammary gland 3' read
BE693805.1 mammary gland
BE693809.1 mammary gland
CX784829.1 Clone IMAGE:7479285 embryonic tissue 5' read P
BE788492.1 Clone IMAGE:3878834 lung 5' read
BE885521.1 Clone IMAGE:3910395 uterus 5' read P
BE927173.1 intestine
BE927186.1 intestine
AV710901.1 Clone CuAADC11 adrenal gland 5' read A
CT002618.1 Clone RZPDp9016I1631 uncharacterized tissue 5' read
DR763161.1 Clone IMAGE:7973089 embryonic tissue 5' read P
BF111989.1 Clone IMAGE:3523577 mixed 3' read
AU126857.1 Clone NT2RP2000088 testis 5' read
BF245394.1 Clone IMAGE:4081125 brain 5' read
H60602.1 Clone IMAGE:208126 mixed 5' read
BF377148.1 testis
AA861517.1 Clone IMAGE:1407666 testis 3' read
DA339278.1 Clone BRHIP3041085 brain 5' read P
DA084211.1 Clone BRACE2038259 brain 5' read
DA084405.1 Clone BRACE2038497 brain 5' read P
DA125979.1 Clone BRACE3048831 brain 5' read P
DA020435.1 Clone ASTRO2001803 brain 5' read P
DA284212.1 Clone BRCOC2014134 brain 5' read
DA024306.1 Clone ASTRO2006879 brain 5' read P
DA169525.1 Clone BRAMY2031390 brain 5' read P
DA248305.1 Clone BRAWH3047697 brain 5' read P
DA182950.1 Clone BRAMY3000374 brain 5' read P
DA107578.1 Clone BRACE3022383 brain 5' read P
DA264737.1 Clone BRCAN2017775 brain 5' read P
DA338904.1 Clone BRHIP3040516 brain 5' read P
DA161161.1 Clone BRAMY2021315 brain 5' read P
DA338996.1 Clone BRHIP3040660 brain 5' read P
DA502567.1 Clone FCBBF3017169 brain 5' read P
DA503317.1 Clone FCBBF3018144 brain 5' read
DA498661.1 Clone FCBBF3012098 brain 5' read P
DA623078.1 Clone KIDNE2002455 kidney 5' read P
DA591956.1 Clone HLUNG2014285 lung 5' read P
DA507728.1 Clone FCBBF3023838 brain 5' read P
DA553266.1 Clone HCHON2003042 connective tissue 5' read P
DA632158.1 Clone KIDNE2013692 kidney 5' read
DA627557.1 Clone KIDNE2008118 kidney 5' read
DA490904.1 Clone FCBBF3002241 brain 5' read P
AU140274.1 Clone PLACE2000246 placenta 5' read P
DA376107.1 Clone BRTHA2007644 brain 5' read
DA500585.1 Clone FCBBF3014580 brain 5' read P
DA645216.1 Clone LYMPB2002368 blood 5' read P
AU149635.1 Clone NT2RP2000088 testis 3' read A
DA954946.1 Clone SPLEN2033429 spleen 5' read P
DA772246.1 Clone OCBBF2005419 brain 5' read
DA766331.1 Clone NTONG2007500 mouth 5' read P
DA700744.1 Clone NT2RI2003225 5' read
DA700748.1 Clone NT2RI2003230 5' read P
BF432454.1 Clone IMAGE:3406352 brain 3' read
DA703483.1 Clone NT2RI2006610 5' read P
DA776348.1 Clone OCBBF2010477 brain 5' read P
DA809509.1 Clone OCBBF3025779 brain 5' read P
DA901605.1 Clone SKNMC2001114 brain 5' read P
DA778872.1 Clone OCBBF2013614 brain 5' read P
DA707221.1 Clone NT2RI2011584 5' read P
DA936381.1 Clone SPLEN2008495 spleen 5' read
DA794562.1 Clone OCBBF2034978 brain 5' read P
BF508711.1 Clone IMAGE:3085693 uncharacterized tissue 3' read A
DA789302.1 Clone OCBBF2027544 brain 5' read P
DB264298.1 Clone UTERU2023146 uterus 5' read P
DB197836.1 Clone TRACH2005343 trachea 5' read P
DB237547.1 Clone TRACH3033246 trachea 5' read P
DB126306.1 Clone THYMU2036024 thymus 5' read P
DB102742.1 Clone THYMU2002121 thymus 5' read
DB137893.1 Clone THYMU3009858 thymus 5' read
T34063.1 blood 5' read
BF902015.1 blood
BG177909.1 Clone IMAGE:4429062 prostate 5' read
DB461936.1 Clone H013096F04 testis 5' read P
DB516897.1 Clone H013053F14 testis 3' read A
DB523525.1 Clone H013080D13 testis 3' read A
BG255772.1 Clone IMAGE:4476349 prostate 5' read P
DB451422.1 Clone H013053F14 testis 5' read P
DB527358.1 Clone H013096F04 testis 3' read A
DB458035.1 Clone H013080D13 testis 5' read P
EC459128.1 prostate
BG430581.1 Clone IMAGE:4615689 kidney 5' read
BG644306.1 embryonic tissue 5' read
BI037350.1 brain
BI223467.1 Clone IMAGE:5106045 cervix 5' read
BI868750.1 Clone IMAGE:5402301 liver 5' read
CU454547.1 skin
BM141828.1 Clone IMAGE:5677347 pancreas 3' read
BM142120.1 Clone IMAGE:5677347 pancreas 5' read
BM452344.1 Clone IMAGE:5493645 eye 5' read P
BM468566.1 Clone IMAGE:5578173 skin 5' read P
BM542400.1 Clone IMAGE:5539576 skin 5' read A
BM666772.1 Clone UI-E-CL1-aez-o-23-0-UI eye 3' read A
BM692363.1 Clone UI-E-CL1-aes-d-04-0-UI eye 5' read
BM696639.1 Clone UI-E-DW0-agk-i-22-0-UI eye 5' read
BM702476.1 Clone UI-E-CQ1-aez-o-23-0-UI brain 5' read A
BM789053.1 Clone S22SNU16n1-6-A07 ascites 5' read
BM910027.1 Clone IMAGE:5442354 brain 5' read
BM976127.1 Clone UI-CF-EN1-acy-m-12-0-UI lung 3' read A
AL698842.1 Clone DKFZp686O0510 muscle 5' read
AL704912.1 Clone DKFZp686J1433 muscle 5' read
AL712008.1 Clone DKFZp686C1986 muscle 5' read P
W93364.1 Clone IMAGE:357177 heart 3' read A
W93451.1 Clone IMAGE:357177 heart 5' read
BQ436073.1 Clone IMAGE:6013757 uncharacterized tissue 5' read P
AA029357.1 Clone IMAGE:470327 uterus 5' read
AA029358.1 Clone IMAGE:470327 uterus 3' read
BQ707072.1 Clone IMAGE:6279615 spleen 5' read
BQ929509.1 Clone IMAGE:6472318 uterus 5' read
BU167240.1 Clone IMAGE:6162098 skin 5' read
BU172490.1 Clone IMAGE:6164008 skin 5' read P
AA099423.1 Clone IMAGE:510632 intestine 3' read
AA101904.1 Clone IMAGE:510632 intestine 5' read
W25769.1 eye
C04388.1 Clone 3NHC3235 heart
AA130572.1 Clone IMAGE:586686 intestine 3' read A
AA134523.1 Clone IMAGE:586686 intestine 5' read
BU558095.1 Clone IMAGE:6586341 mammary gland 5' read P
BU624153.1 Clone UI-H-FG1-bgj-c-12-0-UI bone 3' read A
BU625052.1 Clone UI-H-FG1-bgl-l-10-0-UI bone 3' read A
BU634299.1 Clone UI-H-FL1-bgx-e-06-0-UI bone 3' read A
AA195352.1 Clone IMAGE:665233 mixed 5' read
BU675007.1 Clone UI-CF-DU1-aae-j-20-0-UI lung 3' read A
BU735157.1 Clone UI-E-DW0-agk-i-22-0-UI eye 3' read A
HY000224.1 Clone H04D001L04 testis P
HY008522.1 Clone H04D028P13 testis P
HY031549.1 Clone H04D109E23 testis P
HY183511.1 Clone H04D001L04 testis
HY216109.1 Clone H04D109E23 testis P
CA309636.1 Clone UI-H-FT1-bif-d-08-0-UI lung 3' read A
CA398203.1 Clone cs99f01 eye 3' read
CA398204.1 Clone cs99f01 eye 5' read P
CA445864.1 Clone UI-H-EI0-axa-m-12-0-UI connective tissue 3' read A
CA488083.1 Clone IMAGE:6719820 mixed 5' read
AA304280.1 vascular 5' read
AA418936.1 Clone IMAGE:768069 mixed 3' read A
AA426583.1 Clone IMAGE:768069 mixed 5' read
AA482929.1 Clone IMAGE:923384 muscle
AA570494.1 Clone IMAGE:1018308 nerve 3' read A
AA595826.1 Clone IMAGE:1018805 nerve 3' read A
AA757331.1 Clone IMAGE:1326894 mixed 3' read A
AA805629.1 Clone IMAGE:1341330 lymph node 3' read A
AA826933.1 Clone IMAGE:1334984 lymph node 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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