> Kelch-like family member 4 (KLHL4)
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UGID:137775     UniGene Hs.49075     Homo sapiens (human)   KLHL4 Order cDNA clone, Links
Kelch-like family member 4 (KLHL4)

Human protein-coding gene KLHL4. Represented by 137 ESTs from 55 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 137775 - Hs.49075]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_476503.1 KLHL4 gene product H. sapiens 100.0 719
NP_766369.1 kelch-like protein 4 M. musculus 93.4 588
NP_001164413.1 kelch-like protein 5 D. rerio 72.2 764
NP_788894.1 CG17754, isoform D D. melanogaster 60.5 587
NP_001086544.1 kelch-like protein 20 X. laevis 46.6 266
Other hits (2 of 37) [Show all]SpeciesId(%)Len(aa)
XP_003918000.1 PREDICTED: kelch-like protein 4 P. anubis 99.4 717
XP_001083897.2 PREDICTED: kelch-like protein 4-like M. mulatta 98.5 681

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; embryonic tissue; liver; stomach; lung; vascular; mixed; trachea; uterus; uncharacterized tissue; kidney; connective tissue; eye; spleen; skin; heart
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: X
Map position: Xq21.3
UniSTS entry: Chr X KLHL4
UniSTS entry: Chr X WI-13626 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

AK022715.1 Homo sapiens cDNA FLJ12653 fis, clone NT2RM4002075, weakly similar to RING CANAL PROTEIN P
AK023057.1 Homo sapiens cDNA FLJ12995 fis, clone NT2RP3000233, weakly similar to RING CANAL PROTEIN P
NM_019117.4 Homo sapiens kelch-like family member 4 (KLHL4), transcript variant 1, mRNA PA
AB051474.1 Homo sapiens mRNA for KIAA1687 protein, partial cds P
AF284766.1 Homo sapiens kelch-like protein KLHL4c mRNA, complete cds, alternatively spliced P
AF284765.1 Homo sapiens kelch-like protein KLHL4 mRNA, complete cds, alternatively spliced P
BC142652.1 Homo sapiens kelch-like 4 (Drosophila), mRNA (cDNA clone MGC:164878 IMAGE:40148044), complete cds PA
BC146677.1 Homo sapiens kelch-like 4 (Drosophila), mRNA (cDNA clone MGC:165083 IMAGE:40148894), complete cds PA
AK056457.1 Homo sapiens cDNA FLJ31895 fis, clone NT2RP7003680, highly similar to Kelch-like protein 4 P
NM_057162.2 Homo sapiens kelch-like family member 4 (KLHL4), transcript variant 2, mRNA P
BC161675.1 Homo sapiens kelch-like 4 (Drosophila), mRNA (cDNA clone MGC:176725 IMAGE:8862604), complete cds PA
BC140840.1 Homo sapiens kelch-like 4 (Drosophila), mRNA (cDNA clone MGC:176517 IMAGE:9021708), complete cds P
BC140839.1 Homo sapiens kelch-like 4 (Drosophila), mRNA (cDNA clone MGC:176516 IMAGE:9021707), complete cds P
AL832514.1 Homo sapiens mRNA; cDNA DKFZp667K011 (from clone DKFZp667K011) PA
AL831868.1 Homo sapiens mRNA; cDNA DKFZp761P1717 (from clone DKFZp761P1717) PA

EST sequences (137)

R18354.1 Clone IMAGE:30916 brain 5' read
CB108922.1 Clone L3SNU475-29-F09 liver 5' read
AI675789.1 Clone IMAGE:2328207 mixed 3' read
AI679432.1 Clone IMAGE:2255768 stomach 3' read A
AI679942.1 Clone IMAGE:2256152 stomach 3' read A
AI743832.1 Clone IMAGE:2367757 mixed 3' read A
AL036465.2 Clone DKFZp564D0762 brain 5' read A
BX281120.1 Clone IMAGp998B069414_;_IMAGE:4150565 brain P
AI917374.1 Clone IMAGE:2237912 uncharacterized tissue 3' read A
CN255585.1 embryonic tissue 5' read P
CN255586.1 embryonic tissue 5' read P
CN255587.1 embryonic tissue 5' read
CX165910.1 Clone IMAGE:7469522 embryonic tissue 5' read P
DR001254.1 Clone TC110542 brain 5' read P
DR002472.1 Clone TC110541 brain 5' read P
AU117238.1 Clone HEMBA1000959 embryonic tissue 5' read
AU125721.1 Clone NT2RM4002075 testis 5' read P
AU130089.1 Clone NT2RP3000233 testis 5' read P
BF342751.1 Clone IMAGE:4150565 brain 5' read P
BF665986.1 Clone IMAGE:4276260 brain 5' read P
DA339453.1 Clone BRHIP3041371 brain 5' read P
DA195337.1 Clone BRAMY4000754 brain 5' read P
DA234842.1 Clone BRAWH3031133 brain 5' read P
DA189554.1 Clone BRAMY3011466 brain 5' read P
DA228847.1 Clone BRAWH3023315 brain 5' read P
DA228874.1 Clone BRAWH3023356 brain 5' read P
DA241308.1 Clone BRAWH3039069 brain 5' read P
DA196026.1 Clone BRAMY4001605 brain 5' read P
DA241488.1 Clone BRAWH3039283 brain 5' read P
DA229474.1 Clone BRAWH3024124 brain 5' read P
DA320604.1 Clone BRHIP3013400 brain 5' read P
DA242516.1 Clone BRAWH3040528 brain 5' read P
DA236066.1 Clone BRAWH3032656 brain 5' read P
DA236069.1 Clone BRAWH3032659 brain 5' read P
DA236523.1 Clone BRAWH3033206 brain 5' read P
DA119912.1 Clone BRACE3040484 brain 5' read
DA348729.1 Clone BRSSN2010665 brain 5' read P
DA021557.1 Clone ASTRO2003269 brain 5' read P
DA283660.1 Clone BRCOC2013339 brain 5' read P
DA244349.1 Clone BRAWH3042794 brain 5' read P
DA238501.1 Clone BRAWH3035652 brain 5' read P
DA245404.1 Clone BRAWH3044085 brain 5' read P
DA212300.1 Clone BRAWH3001735 brain 5' read P
DA206728.1 Clone BRAWH2013566 brain 5' read P
DA128375.1 Clone BRACE3051932 brain 5' read P
DA324293.1 Clone BRHIP3018759 brain 5' read P
DA174762.1 Clone BRAMY2037950 brain 5' read P
DA135846.1 Clone BRALZ2008933 brain 5' read P
DA247024.1 Clone BRAWH3046119 brain 5' read P
DA247609.1 Clone BRAWH3046855 brain 5' read P
DA260038.1 Clone BRCAN2011932 brain 5' read P
DA221395.1 Clone BRAWH3013427 brain 5' read P
DA248474.1 Clone BRAWH3047933 brain 5' read P
DA333470.1 Clone BRHIP3032316 brain 5' read P
DA333708.1 Clone BRHIP3032698 brain 5' read P
DA183942.1 Clone BRAMY3002063 brain 5' read P
DA099806.1 Clone BRACE3011361 brain 5' read P
DA185341.1 Clone BRAMY3004508 brain 5' read P
DA218999.1 Clone BRAWH3010333 brain 5' read P
DA107191.1 Clone BRACE3021846 brain 5' read P
DA342538.1 Clone BRSSN2002290 brain 5' read P
DA192229.1 Clone BRAMY3015522 brain 5' read P
DA226286.1 Clone BRAWH3019971 brain 5' read P
DA226535.1 Clone BRAWH3020294 brain 5' read P
DA194543.1 Clone BRAMY3018960 brain 5' read P
DA233905.1 Clone BRAWH3029941 brain 5' read P
DA149018.1 Clone BRAMY2006429 brain 5' read P
DA497411.1 Clone FCBBF3010486 brain 5' read
DA392596.1 Clone BRTHA2030693 brain 5' read
DA498187.1 Clone FCBBF3011456 brain 5' read P
DA393420.1 Clone BRTHA2031873 brain 5' read P
DA388287.1 Clone BRTHA2024385 brain 5' read P
DA590534.1 Clone HLUNG2012488 lung 5' read P
DA697848.1 Clone NT2NE2019129 5' read P
DA403454.1 Clone BRTHA3007577 brain 5' read P
DA403781.1 Clone BRTHA3008051 brain 5' read P
DA399790.1 Clone BRTHA3002466 brain 5' read P
DA406647.1 Clone BRTHA3011996 brain 5' read P
DA406979.1 Clone BRTHA3012423 brain 5' read P
DA494703.1 Clone FCBBF3007093 brain 5' read P
AU149324.1 Clone NT2RM4002075 testis 3' read
AU152117.1 Clone NT2RP3000233 testis 3' read A
DA725243.1 Clone NT2RI3006855 testis 5' read P
DA759257.1 Clone NT2RP8007559 testis 5' read
DA726876.1 Clone NT2RI3008977 testis 5' read P
DA811534.1 Clone OCBBF3028500 brain 5' read P
DA806393.1 Clone OCBBF3021772 brain 5' read P
DA885211.1 Clone PUAEN2005210 vascular 5' read P
DA741081.1 Clone NT2RP7003680 testis 5' read P
DA886060.1 Clone PUAEN2006308 vascular 5' read P
DA729789.1 Clone NT2RM2003987 testis 5' read P
DA808676.1 Clone OCBBF3024676 brain 5' read P
DA769959.1 Clone OCBBF2002546 brain 5' read P
DA887269.1 Clone PUAEN2007713 vascular 5' read P
DA712447.1 Clone NT2RI2018696 5' read P
DA936946.1 Clone SPLEN2009506 spleen 5' read P
DA720567.1 Clone NT2RI3000741 testis 5' read P
DA721991.1 Clone NT2RI3002623 testis 5' read P
DA715799.1 Clone NT2RI2023180 5' read P
DA788128.1 Clone OCBBF2025944 brain 5' read P
DA722154.1 Clone NT2RI3002853 testis 5' read P
DA757745.1 Clone NT2RP8005093 testis 5' read P
DB080460.1 Clone TESTI4026030 testis 5' read P
DB081217.1 Clone TESTI4027110 testis 5' read P
DB081529.1 Clone TESTI4027569 testis 5' read P
DB076325.1 Clone TESTI4020514 testis 5' read P
DB227229.1 Clone TRACH3019670 trachea 5' read P
DB083610.1 Clone TESTI4030299 testis 5' read P
DB077215.1 Clone TESTI4021759 testis 5' read P
DB092209.1 Clone TESTI4041763 testis 5' read P
DB092828.1 Clone TESTI4042577 testis 5' read P
DB354981.1 Clone HEMBA1000959 embryonic tissue 3' read
DB284650.1 Clone UTERU3012649 uterus 5' read P
DB062396.1 Clone TESTI4002522 testis 5' read P
DB279220.1 Clone UTERU3005503 uterus 5' read P
DB324706.1 Clone NT2RP7003680 testis 3' read
DB096450.1 Clone TESTI4047388 testis 5' read P
DB070474.1 Clone TESTI4013028 testis 5' read P
DB071142.1 Clone TESTI4013875 testis 5' read P
DB071383.1 Clone TESTI4014187 testis 5' read P
DB072109.1 Clone TESTI4015106 testis 5' read P
DB178900.1 Clone TKIDN2016233 kidney 5' read P
DB519857.1 Clone H013065H10 testis 3' read A
DB454423.1 Clone H013065H10 testis 5' read P
DB475028.1 Clone H023065K12 brain 5' read P
DB543853.1 Clone H023065K12 brain 3' read A
DT216215.1 brain
BG196070.1 connective tissue A
N63289.1 Clone IMAGE:290172 brain 3' read
N64817.1 Clone IMAGE:284664 brain 3' read A
N75668.1 Clone IMAGE:244152 mixed 5' read
N90812.1 Clone IMAGE:290172 brain 5' read
BM718564.1 Clone UI-E-EO1-ajb-f-08-0-UI eye 5' read
ES315786.1 skin
AA054300.1 Clone IMAGE:489367 uterus 5' read P
BU743007.1 Clone UI-E-EO1-ajb-f-08-0-UI eye 3' read A
AA247484.1 heart 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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