> Islet amyloid polypeptide (IAPP)
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UGID:137452     UniGene Hs.46835     Homo sapiens (human)   IAPP Links
Islet amyloid polypeptide (IAPP)

Human protein-coding gene IAPP. Represented by 331 ESTs from 11 cDNA libraries. EST representation biased toward pancreas; pancreatic tumor; adult. Corresponds to reference sequence NM_000415.2. [UniGene 137452 - Hs.46835]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000406.1 IAPP gene product H. sapiens 100.0 88
Other hits (2 of 3) [Show all]SpeciesId(%)Len(aa)
XP_001144800.2 PREDICTED: uncharacterized protein LOC741937 P. troglodytes 98.9 88
XP_001098180.1 PREDICTED: islet amyloid polypeptide isoform 1 M. mulatta 97.8 88

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: pancreas [show more like this]
pancreatic tumor [show more like this]
adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: pancreas; connective tissue; testis; mixed
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12p12.1
UniSTS entry: Chr 12 SHGC-57392
UniSTS entry: Chr 1 D11S2560
UniSTS entry: Chr 12 SGC35306 [Map Viewer]
UniSTS entry: Chr 1 D15S1477
UniSTS entry: Chr 12 IAPP_3999
UniSTS entry: Chr 1 D11S3114
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

NM_000415.2 Homo sapiens islet amyloid polypeptide (IAPP), mRNA PA
J04422.1 Human islet amyloid protein mRNA, complete cds P
DQ516082.1 Homo sapiens islet amyloid polypeptide precursor (IAPP) mRNA, complete cds P
X14904.1 Human IAPP mRNA for islet amyloid polypeptide precursor (IAP-cI) P
X14905.1 Human IAPP mRNA 5' region for islet amyloid polypeptide precursor (IAP-c2)

EST sequences (331)

CB066870.1 Clone IMAGE: pancreas 3' read
CB066979.1 Clone IMAGE: pancreas 3' read
CB067250.1 Clone IMAGE: pancreas 5' read P
CB067357.1 Clone IMAGE: pancreas 3' read
CB067140.1 Clone IMAGE: pancreas 5' read
CB067525.1 Clone IMAGE: pancreas 3' read A
CB067656.1 Clone IMAGE: pancreas 5' read P
CB067823.1 Clone IMAGE: pancreas 5' read P
CB068009.1 Clone IMAGE:6216947 pancreas 3' read
CB068471.1 Clone IMAGE:6365203 pancreas 3' read
CB069026.1 Clone IMAGE:6554304 pancreas 5' read
CB069195.1 Clone IMAGE:6364787 pancreas 3' read A
CB069586.1 Clone IMAGE:6553533 pancreas 3' read
CB069987.1 Clone IMAGE:6553840 pancreas 5' read
CB070065.1 Clone IMAGE:6553533 pancreas 5' read P
CB177389.1 Clone IMAGE:6365203 pancreas 5' read P
BX281620.1 Clone IMAGp998L1912477_;_IMAGE:5633826 pancreas
AW582904.1 Clone IMAGE:5637625 pancreas 5' read P
AW582958.1 Clone IMAGE:5637711 pancreas 5' read P
AW584023.1 Clone IMAGE:5637757 pancreas 3' read A
CK826494.1 Clone IMAGE:6133066 pancreas 3' read P
CK826495.1 Clone IMAGE:6133066 pancreas 5' read A
CK905016.1 Clone IMAGE:5637625 pancreas 5' read P
BP322325.1 Clone PNC02052 pancreas 5' read P
BP322713.1 Clone PNC03132 pancreas 5' read P
BP323132.1 Clone PNC03961 pancreas 5' read P
BP325149.1 Clone PNC08286 pancreas 5' read P
BP325265.1 Clone PNC08549 pancreas 5' read P
BP384020.1 Clone hbt00278 pancreas 3' read A
BP387333.1 Clone hbt07143 pancreas 3' read A
BP387339.1 Clone hbt07155 pancreas 3' read
BP387600.1 Clone hbt07667 pancreas 3' read
BP388083.1 Clone hbt08698 pancreas 3' read A
BP388324.1 Clone hbt09161 pancreas 3' read
BP388376.1 Clone hbt09272 pancreas 3' read A
BP388426.1 Clone hbt09379 pancreas 3' read A
BP388766.1 Clone hbt10113 pancreas 3' read
BP389435.1 Clone hbt11399 pancreas 3' read
BP389440.1 Clone hbt11408 pancreas 3' read
BP389517.1 Clone hbt11573 pancreas 3' read A
BP389827.1 Clone hbt12233 pancreas 3' read A
BP389902.1 Clone hbt12392 pancreas 3' read A
BP390250.1 Clone h-t-211-41 pancreas 3' read A
BP391287.1 Clone h-t-241-54 pancreas 3' read
BP391451.1 Clone h-t-246-10 pancreas 3' read A
BP391602.1 Clone h-t-250-37 pancreas 3' read A
BP391939.1 Clone h-t-259-80 pancreas 3' read
BP392717.1 Clone htp-11-66 pancreas 3' read
BP393167.1 Clone htp-25-05 pancreas 3' read
BP393373.1 Clone htp-31-86 pancreas 3' read A
BP393651.1 Clone htp-40-48 pancreas 3' read
BP393998.1 Clone htp-51-58 pancreas 3' read A
BP394192.1 Clone htp-57-14 pancreas 3' read
BG654456.1 pancreas 3' read
BG654621.1 pancreas 3' read
BG654815.1 pancreas 5' read P
BG655075.1 pancreas 5' read
BG655484.1 pancreas 3' read
BG655770.1 pancreas 3' read
BG656102.1 pancreas 5' read P
BG656225.1 pancreas 5' read P
BG656535.1 pancreas 3' read
BG187739.1 connective tissue A
BG192865.1 connective tissue A
BG215756.1 connective tissue A
D82641.1 pancreas
D82083.1 pancreas
D82143.1 pancreas P
D82186.1 pancreas
D82228.1 pancreas P
BI324887.1 pancreas 3' read A
BI324997.1 pancreas 3' read
BI438233.1 pancreas 5' read P
BI438793.1 pancreas 3' read
BI439851.1 pancreas 3' read A
BI467066.1 pancreas 5' read P
BI467227.1 pancreas 3' read PA
BI710914.1 Clone IMAGE:5023620 pancreas 5' read
BI711321.1 Clone IMAGE:5023374 pancreas 3' read A
BI711363.1 Clone IMAGE:5023620 pancreas 3' read A
BI711720.1 Clone IMAGE:5023694 pancreas 5' read A
BI712471.1 Clone IMAGE:5086459 pancreas 3' read
BI712594.1 Clone IMAGE:5086708 pancreas 3' read
BI712710.1 Clone IMAGE:5086459 pancreas 5' read P
BI712838.1 Clone IMAGE:5086708 pancreas 5' read P
BI713704.1 Clone IMAGE:5086339 pancreas 3' read
BI715136.1 pancreas 5' read P
BI792111.1 Clone IMAGE:5086339 pancreas 5' read
BI792113.1 Clone IMAGE:5086343 pancreas 5' read
BI792466.1 pancreas 3' read A
BI963878.1 Clone IMAGE:5671585 pancreas 3' read A
BM263392.1 pancreas 3' read
BM263691.1 pancreas 5' read
BM263836.1 pancreas 3' read
BM264133.1 pancreas 5' read P
BM272408.1 pancreas 5' read P
BM272541.1 pancreas 3' read A
BM272773.1 pancreas 5' read P
BM310438.1 pancreas 3' read
BM310990.1 pancreas 5' read P
BM311072.1 pancreas 5' read P
BM311091.1 pancreas 5' read P
BM311289.1 pancreas 3' read A
BM311363.1 pancreas 3' read A
BM311578.1 pancreas 3' read A
BM311687.1 pancreas 3' read
BM311881.1 pancreas 5' read P
BM311954.1 pancreas 5' read P
BM312722.1 pancreas 5' read P
BM313479.1 pancreas 3' read A
BM313606.1 pancreas 5' read
BM313621.1 pancreas 3' read A
BM313886.1 pancreas 5' read P
BM314212.1 pancreas 3' read
BM314275.1 pancreas 3' read
BM314356.1 pancreas 3' read A
BM314519.1 pancreas 5' read
BM314581.1 pancreas 5' read P
BM314664.1 pancreas 5' read P
BM353306.1 pancreas 5' read P
BM353459.1 pancreas 3' read A
BM353568.1 pancreas 3' read
BM353731.1 pancreas 5' read
BM353840.1 pancreas 5' read P
BM503335.1 pancreas 3' read
BM503496.1 pancreas 5' read
BM503831.1 pancreas 5' read P
BM503960.1 pancreas 5' read
BM503966.1 pancreas 5' read P
BM504558.1 pancreas 3' read
BM504821.1 pancreas 3' read
BM504882.1 pancreas 5' read P
BM505146.1 pancreas 5' read
BM505548.1 pancreas 3' read A
BM507333.1 pancreas 5' read
BM508916.1 pancreas 5' read P
BM509142.1 pancreas 3' read A
BM509215.1 pancreas 3' read A
BM509378.1 pancreas 5' read
BM509461.1 pancreas 5' read P
BM509559.1 pancreas 5' read
BM509916.1 pancreas 3' read
BM509975.1 pancreas 3' read
BM510104.1 pancreas 3' read A
BM510693.1 Clone IMAGE:5634155 pancreas 3' read A
BM510895.1 Clone IMAGE:5633826 pancreas 3' read A
BM511148.1 Clone IMAGE:5633826 pancreas 5' read
BM511532.1 Clone IMAGE:5634155 pancreas 5' read
BM512290.1 Clone IMAGE:5636290 pancreas 3' read A
BM512546.1 Clone IMAGE:5636290 pancreas 5' read P
BM565593.1 pancreas 3' read A
W39293.1 Clone IMAGE:328284 pancreas 5' read
W40114.1 Clone IMAGE:328757 pancreas 5' read
BM729954.1 Clone IMAGE:5634650 pancreas 5' read P
W51782.1 Clone IMAGE:338537 pancreas 5' read
BM857649.1 Clone IMAGE:5635969 pancreas 3' read A
BM857823.1 Clone IMAGE:5635969 pancreas 5' read P
BM875368.1 Clone IMAGE:5634893 pancreas 3' read A
BM875620.1 Clone IMAGE:5634893 pancreas 5' read
BM876150.1 Clone IMAGE:5635244 pancreas 3' read P
BM876405.1 Clone IMAGE:5635244 pancreas 5' read A
BM876515.1 Clone IMAGE:5635154 pancreas 5' read P
BQ127906.1 Clone IMAGE:5777800 pancreas 5' read
BQ128171.1 Clone IMAGE:5777800 pancreas 3' read
BQ130707.1 Clone IMAGE:5778430 pancreas 5' read A
BQ269312.1 Clone IMAGE:5781777 pancreas 5' read
BQ270004.1 Clone IMAGE:5782835 pancreas 5' read P
BQ271982.1 Clone IMAGE:5781339 pancreas 5' read P
BQ285955.1 Clone IMAGE:5781777 pancreas 3' read A
BQ287821.1 Clone IMAGE:5783270 pancreas 3' read A
BQ417278.1 Clone IMAGE:5783270 pancreas 5' read P
BQ477320.1 Clone IMAGE:6027306 pancreas 3' read A
BQ477735.1 Clone IMAGE:6027306 pancreas 5' read P
BQ478402.1 Clone IMAGE:6027009 pancreas 5' read
BQ581125.1 Clone IMAGE:6029086 pancreas 5' read
BQ581762.1 Clone IMAGE:6029775 pancreas 3' read A
BQ582100.1 Clone IMAGE:6029775 pancreas 5' read P
BQ613782.1 Clone IMAGE:6030048 pancreas 3' read
BQ613866.1 Clone IMAGE:6030053 pancreas 3' read A
BQ614382.1 Clone IMAGE:6028391 pancreas 3' read A
BQ614491.1 Clone IMAGE:6028449 pancreas 5' read P
BQ614605.1 Clone IMAGE:6028391 pancreas 5' read A
BQ631034.1 Clone IMAGE:6030048 pancreas 5' read P
BQ631105.1 Clone IMAGE:6030053 pancreas 5' read
BQ632122.1 Clone IMAGE:6030891 pancreas 3' read
BQ632141.1 Clone IMAGE:6030628 pancreas 3' read A
BQ632492.1 Clone IMAGE:6031348 pancreas 3' read A
BQ632781.1 Clone IMAGE:6031348 pancreas 5' read
BQ776481.1 Clone IMAGE:6031866 pancreas 3' read
BQ776722.1 Clone IMAGE:6031931 pancreas 3' read
BQ776794.1 Clone IMAGE:6031866 pancreas 5' read
BQ777703.1 Clone IMAGE:6032470 pancreas 3' read A
BU069274.1 Clone IMAGE:6032623 pancreas 3' read
BU069957.1 Clone IMAGE:6035393 pancreas 3' read A
BU070199.1 Clone IMAGE:6035393 pancreas 5' read P
BU071178.1 Clone IMAGE:6036589 pancreas 3' read
BU072008.1 Clone IMAGE:6038719 pancreas 5' read P
BU072012.1 Clone IMAGE:6038727 pancreas 5' read P
BU072050.1 Clone IMAGE:6038915 pancreas 5' read
BU072060.1 Clone IMAGE:6038965 pancreas 5' read
BU072070.1 Clone IMAGE:6039011 pancreas 5' read P
BU072675.1 Clone IMAGE:6038018 pancreas 5' read P
BU073182.1 Clone IMAGE:6036589 pancreas 5' read
BU074561.1 Clone IMAGE:6041133 pancreas 3' read
BU074848.1 Clone IMAGE:6041133 pancreas 5' read P
BU076008.1 Clone IMAGE:6038719 pancreas 3' read A
BU076012.1 Clone IMAGE:6038727 pancreas 3' read
BU076053.1 Clone IMAGE:6038965 pancreas 3' read
BU076061.1 Clone IMAGE:6039011 pancreas 3' read
BU076379.1 Clone IMAGE:6038602 pancreas 3' read
BU076663.1 Clone IMAGE:6038602 pancreas 5' read
BU077596.1 Clone IMAGE:6037213 pancreas 3' read A
BU077803.1 Clone IMAGE:6037213 pancreas 5' read P
BU078067.1 Clone IMAGE:6040003 pancreas 3' read
BU078323.1 Clone IMAGE:6040003 pancreas 5' read P
BU078330.1 Clone IMAGE:6040131 pancreas 5' read P
BU078900.1 Clone IMAGE:6040487 pancreas 3' read A
BU079184.1 Clone IMAGE:6040487 pancreas 5' read P
BQ786844.1 Clone IMAGE:6033439 pancreas 3' read A
BQ787114.1 Clone IMAGE:6033439 pancreas 5' read P
BQ548699.1 Clone IMAGE:6028154 pancreas 3' read A
BQ548857.1 Clone IMAGE:6028154 pancreas 5' read
BQ548915.1 Clone IMAGE:6028075 pancreas 5' read P
BQ549303.1 Clone IMAGE:6029086 pancreas 3' read A
BQ549630.1 Clone IMAGE:6027681 pancreas 3' read A
D83845.1 pancreas P
C05774.1 Clone hbc5139 pancreas
C05814.1 Clone hbc5187 pancreas
C06242.1 Clone hbc4919 pancreas P
C06250.1 Clone hbc4927 pancreas P
C06333.1 Clone hbc5012 pancreas
C06335.1 Clone hbc5014 pancreas A
BU579833.1 Clone IMAGE:6122231 pancreas 3' read A
BU580082.1 Clone IMAGE:6122231 pancreas 5' read P
BU781710.1 Clone IMAGE:6122420 pancreas 5' read P
BU781851.1 Clone IMAGE:6122814 pancreas 5' read P
BU782763.1 Clone IMAGE:6122814 pancreas 3' read A
BU783115.1 Clone IMAGE:6123266 pancreas 3' read
BU783208.1 Clone IMAGE:6123429 pancreas 3' read
BU783359.1 Clone IMAGE:6123266 pancreas 5' read
BU783458.1 Clone IMAGE:6123429 pancreas 5' read P
BU783972.1 Clone IMAGE:6124055 pancreas 3' read A
BU784241.1 Clone IMAGE:6124055 pancreas 5' read P
BU784778.1 Clone IMAGE:6126164 pancreas 3' read
BU785176.1 Clone IMAGE:6124683 pancreas 5' read P
BU786029.1 Clone IMAGE:6129402 pancreas 3' read A
BU786213.1 Clone IMAGE:6129670 pancreas 3' read
BU786257.1 Clone IMAGE:6129563 pancreas 3' read A
BU786516.1 Clone IMAGE:6126164 pancreas 5' read P
BU786844.1 Clone IMAGE:6122420 pancreas 3' read A
BU787662.1 Clone IMAGE:6128459 pancreas 3' read A
BU790193.1 Clone IMAGE:6125816 pancreas 3' read
BU790489.1 Clone IMAGE:6125816 pancreas 5' read P
BU947424.1 Clone IMAGE:6129670 pancreas 5' read P
BU947468.1 Clone IMAGE:6129563 pancreas 5' read P
BU947587.1 Clone IMAGE:6130215 pancreas 3' read A
BU947849.1 Clone IMAGE:6130215 pancreas 5' read P
BU948074.1 Clone IMAGE:6130016 pancreas 3' read A
BU949545.1 Clone IMAGE:6126616 pancreas 3' read A
BU949825.1 Clone IMAGE:6126616 pancreas 5' read P
BU951042.1 Clone IMAGE:6132058 pancreas 5' read P
BU951063.1 Clone IMAGE:6132150 pancreas 5' read
BU951934.1 Clone IMAGE:6128099 pancreas 3' read
BU951995.1 Clone IMAGE:6128130 pancreas 3' read A
BU952261.1 Clone IMAGE:6128130 pancreas 5' read P
BU952487.1 Clone IMAGE:6132058 pancreas 3' read
BU952505.1 Clone IMAGE:6132150 pancreas 3' read
BU952566.1 Clone IMAGE:6132065 pancreas 3' read
T70299.1 Clone IMAGE:109398 mixed 3' read
CA771231.1 Clone IMAGE:6131829 pancreas 3' read A
CA771539.1 Clone IMAGE:6131829 pancreas 5' read P
CA771843.1 Clone IMAGE:6133066 pancreas 3' read A
CA772198.1 Clone IMAGE:6133914 pancreas 5' read P
CA772568.1 Clone IMAGE:6132753 pancreas 5' read P
CA772703.1 Clone IMAGE:6133066 pancreas 5' read P
CA774449.1 Clone IMAGE:6218050 pancreas 3' read
CA774554.1 Clone IMAGE:6218278 pancreas 3' read A
CA774826.1 Clone IMAGE:6216493 pancreas 3' read
CA774951.1 Clone IMAGE:6216457 pancreas 5' read P
CA775090.1 Clone IMAGE:6216493 pancreas 5' read P
CA775528.1 Clone IMAGE:6133439 pancreas 5' read P
CA776373.1 Clone IMAGE:6216240 pancreas 3' read
CA776491.1 Clone IMAGE:6216401 pancreas 3' read PA
CA776609.1 Clone IMAGE:6216240 pancreas 5' read
CA776720.1 Clone IMAGE:6216401 pancreas 5' read P
CA842332.1 Clone IMAGE: pancreas 3' read
CA843016.1 Clone IMAGE:6548863 pancreas 5' read P
CA843125.1 Clone IMAGE:6549146 pancreas 5' read P
CA843470.1 Clone IMAGE:6548560 pancreas 3' read A
CA843720.1 Clone IMAGE:6548560 pancreas 5' read
CA843773.1 Clone IMAGE:6548863 pancreas 3' read
CA865448.1 Clone IMAGE:6547727 pancreas 3' read A
CA865465.1 Clone IMAGE:6547853 pancreas 3' read
CA865711.1 Clone IMAGE:6547853 pancreas 5' read P
CA865690.1 Clone IMAGE:6547727 pancreas 5' read P
CA865893.1 Clone IMAGE:6547740 pancreas 5' read P
CA866140.1 Clone IMAGE:6547555 pancreas 3' read
CA866452.1 Clone IMAGE:6606982 pancreas 5' read
CA867104.1 Clone IMAGE:6549352 pancreas 3' read
CA867745.1 Clone IMAGE:6608953 pancreas 5' read P
CA867814.1 Clone IMAGE:6608954 pancreas 5' read P
CA868197.1 Clone IMAGE:6608514 pancreas 5' read P
CA868507.1 Clone IMAGE:6608953 pancreas 3' read A
CA868571.1 Clone IMAGE:6608954 pancreas 3' read A
CA941111.1 Clone IMAGE:6547555 pancreas 5' read P
CA941120.1 Clone IMAGE:6547597 pancreas 5' read P
CA941361.1 Clone IMAGE:6546979 pancreas 3' read A
CA942137.1 Clone IMAGE:6548325 pancreas 5' read P
CA942400.1 Clone IMAGE:6549352 pancreas 5' read
CA942651.1 Clone IMAGE:6607234 pancreas 3' read
CA942891.1 Clone IMAGE:6607234 pancreas 5' read P
CA943149.1 Clone IMAGE:6216947 pancreas 5' read P
CA943747.1 Clone IMAGE:6609291 pancreas 3' read A
CA943882.1 Clone IMAGE:6609379 pancreas 3' read
CA946671.1 Clone IMAGE:6364318 pancreas 3' read
CA946939.1 Clone IMAGE:6364318 pancreas 5' read P
CA948163.1 Clone IMAGE: pancreas 3' read
CA948433.1 Clone IMAGE: pancreas 5' read P
CA948481.1 Clone IMAGE: pancreas 3' read A
CA948753.1 Clone IMAGE: pancreas 5' read P
CA949506.1 Clone IMAGE: pancreas 3' read
CA949935.1 Clone IMAGE:6609291 pancreas 5' read P
CA950093.1 Clone IMAGE:6609379 pancreas 5' read P
CA950194.1 Clone IMAGE:6609543 pancreas 3' read A
CA950852.1 Clone IMAGE:6609896 pancreas 3' read A
CA951101.1 Clone IMAGE:6609896 pancreas 5' read P
CA952104.1 Clone IMAGE: pancreas 3' read
CA952377.1 Clone IMAGE: pancreas 5' read P
CA952758.1 Clone IMAGE:6226184 pancreas 5' read P
AA429852.1 Clone IMAGE:780957 testis 3' read P
AA446156.1 Clone IMAGE:780957 testis 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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