> Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4)
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UGID:234567     UniGene Hs.439530     Homo sapiens (human)   DYRK4 Order cDNA clone, Links
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4)

Human protein-coding gene DYRK4. Represented by 192 ESTs from 108 cDNA libraries. Corresponds to reference sequence NM_003845.1. [UniGene 234567 - Hs.439530]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003836.1 DYRK4 gene product H. sapiens 100.0 519
NP_997093.2 Dyrk4 gene product M. musculus 86.2 631
XP_693389.3 PREDICTED: dual specificity tyrosine-phosphorylation-regulated kinase 4 D. rerio 70.8 571
NP_523564.1 smell impaired 35A, isoform A D. melanogaster 65.7 484
XP_001695011.1 dual-specificity tyrosine regulated protein kinase 1 C. reinhardtii 65.3 356
NP_001040950.1 Protein MBK-2, isoform d C. elegans 61.8 398
NP_001088793.1 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 X. laevis 61.0 415
XP_960871.1 hypothetical protein NCU06638 N. crassa 58.6 445
NP_001031970.1 YAK1-like protein 1 A. thaliana 52.8 250
NP_012394.1 Yak1p S. cerevisiae 48.3 230
Other hits (2 of 61) [Show all]SpeciesId(%)Len(aa)
XP_522326.3 PREDICTED: dual specificity tyrosine-phosphorylation-regulated kinase 4 isoform 4 P. troglodytes 99.1 545
XP_003905875.1 PREDICTED: LOW QUALITY PROTEIN: dual specificity tyrosine-phosphorylation-regulated kinase 4 P. anubis 97.0 634

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; uncharacterized tissue; lung; mixed; kidney; uterus; eye; lymph node; pancreas; ovary; ear; cervix; trachea; tonsil; connective tissue; mouth; placenta; intestine; embryonic tissue; heart; mammary gland; skin; blood; larynx; stomach; thyroid; ascites; bone; umbilical cord; pituitary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12p13.32
UniSTS entry: Chr 12 RH15741
UniSTS entry: Chr 12 A007I33 [Map Viewer]
UniSTS entry: Chr 12 RH118990
UniSTS entry: Chr 12 DYRK4_8858
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

NM_003845.1 Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4), mRNA PA
AF263541.1 Homo sapiens protein kinase DYRK4 (DYRK4) mRNA, partial cds P
AK292322.1 Homo sapiens cDNA FLJ76059 complete cds, highly similar to Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4), mRNA P
AK311576.1 Homo sapiens cDNA, FLJ18618
AK308702.1 Homo sapiens cDNA, FLJ98743 P
AK308260.1 Homo sapiens cDNA, FLJ98208 P
BC031244.1 Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4, mRNA (cDNA clone MGC:39640 IMAGE:5266287), complete cds PA
AK298979.1 Homo sapiens cDNA FLJ60811 complete cds, highly similar to Dual specificitytyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1) P
AK303744.1 Homo sapiens cDNA FLJ61032 complete cds, highly similar to Dual specific itytyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1) P
GU139746.1 Homo sapiens clone IMAGE:6622648 DYRK4 mRNA, partial sequence PA
GU139743.1 Homo sapiens clone IMAGE:5744824 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4-like (DYRK4) mRNA, partial sequence, alternatively spliced P
GU139744.1 Homo sapiens clone IMAGE:5850288 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4) mRNA, partial cds, alternatively spliced PA
GU139742.1 Homo sapiens clone IMAGE:5420658 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4) mRNA, partial cds, alternatively spliced PA
GU139741.1 Homo sapiens clone IMAGE:3574031 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4) mRNA, partial cds, alternatively spliced PA
GU139740.1 Homo sapiens clone IMAGE:3439581 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4) mRNA, partial cds, alternatively spliced PA
GU139739.1 Homo sapiens clone IMAGE:2909975 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4) mRNA, partial cds, alternatively spliced PA
Y09305.1 H.sapiens mRNA for protein kinase, Dyrk4, partial P
GU139745.1 Homo sapiens clone IMAGE:6429142 noncoding RNA 152/DYRK4 breakpoint junction sequence PA

EST sequences (192)

AA968719.1 Clone IMAGE:1601148 uncharacterized tissue 3' read P
AI028591.1 Clone IMAGE:1644077 testis 3' read P
AI031860.1 Clone IMAGE:1668816 brain 3' read P
AA948356.1 Clone IMAGE:1589397 kidney 3' read P
AI066522.1 Clone IMAGE:1637621 uncharacterized tissue 3' read P
AI159902.1 Clone IMAGE:1704069 brain 3' read P
BX091456.1 Clone IMAGp998I05390_;_IMAGE:202444 mixed P
AI187736.1 Clone IMAGE:1738728 testis 3' read P
CB164202.1 Clone S23N672133-1-D02 stomach 5' read PA
AI291892.1 Clone IMAGE:1894602 placenta 3' read P
AI351230.1 Clone IMAGE:1951109 lung 3' read
AI361723.1 Clone IMAGE:2021925 uncharacterized tissue 3' read P
AI367740.1 Clone IMAGE:1951916 lung 3' read P
AI392671.1 Clone IMAGE:2111901 mixed 3' read
AI458594.1 Clone IMAGE:2150044 lung 3' read P
AI494089.1 Clone IMAGE:2041951 uterus 3' read P
AI522255.1 Clone IMAGE:2138722 kidney 3' read P
AI554789.1 Clone IMAGE:2169171 brain 3' read P
AI798175.1 Clone IMAGE:2347823 mixed 3' read P
AI806777.1 Clone IMAGE:2350645 mixed 3' read P
AI829636.1 Clone IMAGE:2349460 mixed 3' read
AI857717.1 Clone IMAGE:2423283 lung 3' read
AI923089.1 Clone IMAGE:2450416 lung 3' read P
AI923620.1 Clone IMAGE:2448668 lung 3' read P
AI935703.1 Clone IMAGE:2463510 kidney 3' read P
CB988777.1 Clone IMAGE:30341686 placenta 5' read
CB994019.1 Clone IMAGE:30333879 placenta 5' read
BX359109.2 Clone CS0DI053YM19 placenta 3' read P
BX359110.2 Clone CS0DI053YM19 placenta 5' read P
BX383353.2 Clone CS0DJ010YN07 blood 5' read P
AI950223.1 Clone IMAGE:2473578 uncharacterized tissue 3' read P
AI953498.1 Clone IMAGE:2472683 kidney 3' read P
CD251033.1 Clone IMAGE:30385240 pituitary gland 5' read
AW001402.1 Clone IMAGE:2521610 intestine 3' read P
AW014263.1 Clone IMAGE:2709616 uncharacterized tissue 3' read PA
AW022603.1 Clone IMAGE:2485992 ear 5' read PA
AW028596.1 Clone IMAGE:2531320 ovary 3' read PA
AW166538.1 Clone IMAGE:2697543 cervix 3' read P
AW237572.1 Clone IMAGE:2689890 kidney 3' read P
AW276158.1 Clone IMAGE:2757074 brain 3' read P
CK003334.1 Clone IMAGE:30720257 brain 5' read
AW469539.1 Clone IMAGE:2909975 mixed 3' read P
AW579182.1 kidney P
AW581493.1 uncharacterized tissue
AW581510.1 uncharacterized tissue
CK821004.1 Clone IMAGE:5670236 pancreas 3' read PA
CK821005.1 Clone IMAGE:5670236 pancreas 5' read P
AW896231.1 brain
AW951976.1 uncharacterized tissue P
CN359478.1 embryonic tissue 5' read P
AW978003.1 uncharacterized tissue P
BE140443.1 mouth
BE243995.1 Clone TCBAP0414 lymph node P
CV024727.1 mixed 5' read P
H45246.1 Clone IMAGE:182766 mammary gland 3' read P
H45307.1 Clone IMAGE:182766 mammary gland 5' read
BE720583.1 larynx
BE793321.1 Clone IMAGE:3942718 lung 5' read P
BE879310.1 Clone IMAGE:3887486 lung 5' read P
BP418642.1 Clone HIE01809r intestine 3' read P
H53092.1 Clone IMAGE:202444 mixed 3' read P
H53198.1 Clone IMAGE:202444 mixed 5' read P
DA267205.1 Clone BRCAN2020811 brain 5' read P
DA307013.1 Clone BRHIP2023733 brain 5' read P
DA236096.1 Clone BRAWH3032691 brain 5' read P
DA095347.1 Clone BRACE3005138 brain 5' read
DA144033.1 Clone BRAMY2000114 brain 5' read P
AW604709.1 intestine
AW604710.1 intestine
AW611855.1 Clone IMAGE:2952824 kidney 3' read P
AU142957.1 Clone Y79AA1001162 eye 5' read P
BF431376.1 Clone IMAGE:3574031 kidney 3' read P
DB038497.1 Clone TESTI2024782 testis 5' read P
DA712240.1 Clone NT2RI2018414 5' read P
DB022038.1 Clone TESTI2002859 testis 5' read
DB023044.1 Clone TESTI2004146 testis 5' read
DB024088.1 Clone TESTI2005497 testis 5' read
BF591448.1 Clone IMAGE:3320079 intestine 3' read PA
DB027839.1 Clone TESTI2010499 testis 5' read P
DB027918.1 Clone TESTI2010605 testis 5' read P
DB336164.1 Clone TESTI2004146 testis 3' read P
DB310243.1 Clone BRSSN2007209 brain 3' read P
DB082653.1 Clone TESTI4029062 testis 5' read P
DB350244.1 Clone TRACH3029877 trachea 3' read P
DB306083.1 Clone BRAWH3043804 brain 3' read P
DB339509.1 Clone TESTI4004457 testis 3' read P
DB250749.1 Clone UTERU2004436 uterus 5' read P
DB061610.1 Clone TESTI4001514 testis 5' read P
DB207182.1 Clone TRACH2019727 trachea 5' read P
DB057048.1 Clone TESTI2049061 testis 5' read P
DB063868.1 Clone TESTI4004457 testis 5' read
DB181007.1 Clone TKIDN2019122 kidney 5' read P
DB328958.1 Clone PLACE7009959 placenta 3' read
BF975826.1 Clone IMAGE:4337307 tonsil 5' read P
BF940132.1 Clone IMAGE:3439581 brain 3' read P
BG163292.1 Clone IMAGE:4446792 kidney 5' read P
DB462088.1 Clone H013096P22 testis 5' read P
DB516500.1 Clone H013051K12 testis 3' read P
DB501207.1 Clone H033079J09 brain 5' read P
DB442809.1 Clone H013006E05 testis 5' read
DB572396.1 Clone H033079J09 brain 3' read P
DB449240.1 Clone H013040I10 testis 5' read P
DB507712.1 Clone H013006E05 testis 3' read P
DB527520.1 Clone H013096P22 testis 3' read P
DB514267.1 Clone H013040I10 testis 3' read P
AL561373.3 Clone CS0DL007YJ21 uncharacterized tissue 3' read P
AL561394.3 Clone CS0DL007YJ21 uncharacterized tissue 5' read P
AL561586.3 Clone CS0DL011YI01 uncharacterized tissue 5' read P
AL582755.3 Clone CS0DL011YI01 uncharacterized tissue 3' read P
BG185228.1 connective tissue A
BG192039.1 connective tissue PA
BG201741.1 connective tissue PA
BG207483.1 connective tissue P
BG208541.1 connective tissue PA
BG215397.1 connective tissue PA
N55863.1 Clone J3463 heart 5' read P
N67478.1 Clone IMAGE:291833 skin 3' read
BI018630.1 blood A
BI018635.1 blood A
BI005054.1 thyroid
BG953152.1 intestine
BG721331.1 Clone IMAGE:4827089 testis 5' read P
BI459242.1 Clone IMAGE:5266287 testis 5' read P
DC412384.1 Clone TKIDN2014606 kidney 5' read P
DC396202.1 Clone TESTI2016085 testis 5' read P
BI559381.1 Clone IMAGE:5295423 testis 5' read P
N95016.1 Clone IMAGE:306523 lung 3' read P
BI830824.1 Clone IMAGE:5172729 brain 5' read A
BI792824.1 Clone IMAGE:5670236 pancreas 3' read PA
BI793078.1 Clone IMAGE:5670236 pancreas 5' read P
BI857390.1 Clone IMAGE:5393529 mammary gland 5' read P
W03407.1 Clone IMAGE:291833 skin 5' read P
BM041899.1 Clone IMAGE:5420559 skin 5' read PA
BM042626.1 Clone IMAGE:5420559 skin 3' read
BM042712.1 Clone IMAGE:5420658 skin 3' read P
BM452073.1 Clone IMAGE:5492992 eye 5' read PA
BM560484.1 Clone IMAGE:5744824 brain 5' read P
BM681839.1 Clone UI-E-EJ0-aiq-i-03-0-UI eye 3' read PA
BM684103.1 Clone UI-E-EJ1-aji-m-01-0-UI eye 3' read PA
BM708803.1 Clone UI-E-CI1-afv-o-14-0-UI eye 5' read P
BM719743.1 Clone UI-E-EJ1-aji-m-01-0-UI eye 5' read P
BM723524.1 Clone UI-E-EJ0-aiq-i-03-0-UI eye 5' read PA
BM761885.1 Clone S13KMS5-6-A02 stomach 5' read P
BM792570.1 Clone S22SNU16n1-24-F02 ascites 5' read P
W78116.1 Clone IMAGE:346879 heart 3' read P
W79823.1 Clone IMAGE:346879 heart 5' read P
BM969445.1 Clone UI-CF-DU1-abb-g-01-0-UI lung 3' read PA
BM988407.1 Clone IMAGE:3110068 connective tissue 3' read PA
BQ018745.1 Clone IMAGE:5823715 connective tissue 3' read PA
BQ181271.1 Clone IMAGE:5850288 connective tissue 3' read PA
BQ359362.1 thyroid P
BQ774250.1 Clone UI-H-EZ1-bca-c-14-0-UI bone 3' read PA
BG057711.1 Clone IMAGE:4140686 blood 3' read P
BM150381.1 Clone TCBAP0414 lymph node A
BM150567.1 Clone TCBAP1103 lymph node
BQ956879.1 Clone IMAGE:6429142 lung 5' read P
BU532332.1 Clone IMAGE:6557881 mixed 5' read PA
GD136299.1 3' read A
AA083468.1 Clone IMAGE:549128 umbilical cord 3' read P
AA083586.1 Clone IMAGE:549128 umbilical cord 5' read P
C01058.1 uncharacterized tissue
C03572.1 Clone 3NHC1804 heart
FN122429.1 Clone 177256_2377_4030
BU570776.1 Clone IMAGE:6622648 testis 5' read P
AA223545.1 Clone IMAGE:650804 testis 3' read P
AA223535.1 Clone IMAGE:650804 testis 5' read
BU731498.1 Clone UI-E-CI1-afv-o-14-0-UI eye 3' read PA
HY016714.1 Clone H04D057A15 testis P
HY019292.1 Clone H04D065I18 testis P
HY020859.1 Clone H04D070I11 testis P
HY024622.1 Clone H04D083M01 testis
HY197446.1 Clone H04D045P06 testis P
HY199883.1 Clone H04D057A15 testis P
HY203902.1 Clone H04D070I11 testis P
HY208101.1 Clone H04D083M01 testis P
CA444424.1 Clone UI-H-DH1-awq-h-16-0-UI connective tissue 3' read PA
AA314672.1 intestine 5' read P
CA748735.1 Clone UI-H-FT1-bhy-l-02-0-UI lung 3' read PA
AA347295.1 heart 5' read
AA292547.1 Clone IMAGE:723882 ovary 5' read P
AA450003.1 Clone IMAGE:788286 embryonic tissue 3' read P
AA452617.1 Clone IMAGE:788286 embryonic tissue 5' read P
AA481704.1 Clone IMAGE:756601 ovary 5' read P
AA524246.1 Clone IMAGE:936658 intestine 3' read P
T93305.1 Clone IMAGE:119127 lung 3' read
T93981.1 Clone IMAGE:119127 lung 5' read P
AA583761.1 Clone IMAGE:1088164 larynx 3' read PA
AA609677.1 Clone IMAGE:1031823 testis 3' read P
AA777841.1 Clone IMAGE:448718 mixed 3' read
AA805271.1 Clone IMAGE:1338299 lymph node 3' read PA
AA811827.1 Clone IMAGE:1333746 lymph node 3' read PA
AA883519.1 Clone IMAGE:1467422 mixed 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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