> Clock circadian regulator (CLOCK)
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UGID:232012     UniGene Hs.436975     Homo sapiens (human)   CLOCK
Clock circadian regulator (CLOCK)

Human protein-coding gene CLOCK. Represented by 303 ESTs from 166 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 232012 - Hs.436975]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001143582.1 PREDICTED: circadian locomoter output cycles protein kaput isoform 2 P. troglodytes 100.0 846
NP_001254772.1 CLOCK gene product H. sapiens 100.0 845
XP_003898923.1 PREDICTED: circadian locomoter output cycles protein kaput isoform 1 P. anubis 99.9 846
XP_002804151.1 PREDICTED: circadian locomoter output cycles protein kaput-like M. mulatta 99.5 822
NP_031741.1 Clock gene product M. musculus 97.5 854
NP_001083854.2 clock homolog X. laevis 86.1 824
NP_571032.1 clock gene product D. rerio 82.0 847
NP_523964.2 clock, isoform A D. melanogaster 58.7 372
Other hits (2 of 28) [Show all]SpeciesId(%)Len(aa)
XP_003356992.1 PREDICTED: circadian locomoter output cycles protein kaput S. scrofa 99.0 402
XP_532376.3 PREDICTED: circadian locomoter output cycles protein kaput C. lupus familiaris 98.8 845

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: mixed; uncharacterized tissue; brain; prostate; lung; intestine; embryonic tissue; vascular; muscle; mouth; thyroid; testis; eye; skin; bone marrow; placenta; pancreas; uterus; kidney; mammary gland; liver; ovary; connective tissue; parathyroid; pituitary gland; adipose tissue; heart; thymus; trachea; tonsil; bladder; ascites; ganglia; nerve; bone; lymph node; spleen; adrenal gland; pharynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q12
UniSTS entry: Chr 4 STS-R80639
UniSTS entry: Chr 4 SHGC-67841 [Map Viewer]
UniSTS entry: Chr 4 G54151
UniSTS entry: Chr 4 SHGC-59220 [Map Viewer]
UniSTS entry: Chr 4 RH121148
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

BC041878.1 Homo sapiens clock homolog (mouse), mRNA (cDNA clone MGC:43753 IMAGE:5272026), complete cds PA
BX538337.1 Homo sapiens mRNA; cDNA DKFZp686I23208 (from clone DKFZp686I23208) A
BX537616.1 Homo sapiens mRNA; cDNA DKFZp686A09173 (from clone DKFZp686A09173) PA
NM_004898.3 Homo sapiens clock circadian regulator (CLOCK), transcript variant 2, mRNA P
AK223549.1 Homo sapiens mRNA for clock variant, clone: FCC126E10 P
BC126157.1 Homo sapiens clock homolog (mouse), mRNA (cDNA clone MGC:161435 IMAGE:8991873), complete cds P
BC126159.1 Homo sapiens clock homolog (mouse), mRNA (cDNA clone MGC:161437 IMAGE:8991875), complete cds P
AK291708.1 Homo sapiens cDNA FLJ78672 complete cds, highly similar to Homo sapiens clock homolog (mouse) (CLOCK), mRNA P
AK096319.1 Homo sapiens cDNA FLJ39000 fis, clone NT2RI2022468
NM_001267843.1 Homo sapiens clock circadian regulator (CLOCK), transcript variant 1, mRNA P
BC040570.1 Homo sapiens cDNA clone IMAGE:5267398 A
AB002332.1 Homo sapiens mRNA for KIAA0334 gene, partial cds P
AF011568.1 Homo sapiens CLOCK mRNA, complete cds P

EST sequences (303)

AI040999.1 Clone IMAGE:1641799 testis 3' read
AI088169.1 Clone IMAGE:1683302 parathyroid 3' read
AI088667.1 Clone IMAGE:1696228 uterus 3' read
AI088725.1 Clone IMAGE:1686950 brain 3' read A
CB050812.1 Clone IMAGE:3272039 prostate 3' read A
BX103433.1 Clone IMAGp998H031781_;_IMAGE:726194 ovary A
BX097215.1 Clone IMAGp998M011891_;_IMAGE:768552 mixed P
AI188144.1 Clone IMAGE:1734393 testis 3' read A
AI267567.1 Clone IMAGE:2038263 brain P
CB160973.1 Clone L18POOL1n1-24-B04 liver 5' read PA
CB154001.1 Clone B1T694954-32-A05 brain 5' read
AA907920.1 Clone IMAGE:1524386 mixed 3' read A
AI272643.1 Clone IMAGE:1876588 mixed 3' read
AI288889.1 Clone IMAGE:1879708 mixed 3' read P
AI302127.1 Clone IMAGE:1898729 lung 3' read
AI357563.1 Clone IMAGE:2011998 brain 3' read
AI420032.1 Clone IMAGE:2094122 prostate 3' read A
AI435984.1 Clone IMAGE:2124481 mixed 3' read
AI535988.1 prostate 3' read
AI611808.1 Clone IMAGE:2259768 brain 3' read A
AI613068.1 Clone IMAGE:2284372 kidney 3' read
AI630971.1 Clone IMAGE:2273370 lung 3' read
AI636144.1 Clone IMAGE:2288985 uterus 3' read
AI654142.1 Clone IMAGE:2283660 kidney 3' read A
AI656112.1 Clone IMAGE:2243048 uncharacterized tissue 3' read A
AI659092.1 Clone IMAGE:2250411 prostate 3' read
AI688705.1 Clone IMAGE:2330620 mixed 3' read
AI809883.1 Clone IMAGE:2359881 mixed 3' read A
CB270760.1 adipose tissue 5' read
AI816849.1 Clone IMAGE:2404757 kidney 3' read A
AI823476.1 Clone IMAGE:2384586 kidney 3' read
AI824501.1 Clone IMAGE:2274985 uterus 3' read A
AI928105.1 Clone IMAGE:2464503 kidney 3' read
CB994532.1 Clone IMAGE:30333198 placenta 5' read
CD103161.1 Clone IMAGE:30371479 mixed 5' read
AI948677.1 Clone IMAGE:2472200 kidney 3' read
CB852093.1 Clone UI-CF-FN0-aeo-f-12-0-UI lung 3' read
CB853002.1 Clone UI-CF-FN0-afh-f-06-0-UI lung 3' read A
AI956073.1 Clone IMAGE:2509369 pancreas 3' read A
CD237119.1 pituitary gland A
CD359988.1 Clone IMAGE:30388106 testis 5' read P
AW015338.1 Clone IMAGE:2710133 uncharacterized tissue 3' read A
AW016674.1 Clone IMAGE:2711444 uncharacterized tissue 3' read P
BX480578.1 Clone DKFZp686E07222 muscle 5' read P
BX497924.1 Clone DKFZp779H1336 liver 5' read
BX501313.1 Clone DKFZp779B0862 liver 5' read P
BX502325.1 Clone DKFZp779F0568 liver 5' read
CD673731.1 Clone fs03f05 eye 5' read
CD673735.1 Clone fs03f09 eye 5' read
CD677147.1 Clone ho12b04 eye 5' read
CD701629.1 pharynx P
AW069711.1 Clone HBMSC_cr51a03 bone marrow 3' read A
AW130851.1 Clone IMAGE:2612807 uterus 3' read
AW170657.1 Clone IMAGE:2658150 uterus 3' read
BX642325.1 Clone DKFZp686N23267 muscle 5' read
BX642326.1 Clone DKFZp686N23267 muscle 3' read A
BX642796.1 Clone DKFZp781J2416 uncharacterized tissue 5' read
AW238724.1 Clone IMAGE:2741919 mouth 3' read
AL134136.1 Clone DKFZp547K113 brain 5' read
AW275622.1 Clone IMAGE:2742648 mouth 3' read A
AW297091.1 Clone IMAGE:2729064 uncharacterized tissue 3' read A
AW394165.1 testis
CK299457.1 Clone UI-E-EJ1-ajv-d-21-0-UI eye 3' read A
CK301003.1 Clone UI-E-EJ1-ajr-e-04-0-UI eye 3' read A
AW513307.1 Clone IMAGE:2706717 uterus 3' read
CK823558.1 Clone IMAGE:6136642 pancreas 3' read A
R80639.1 Clone IMAGE:146770 placenta 3' read
BU101812.1 mixed
H00777.1 Clone IMAGE:150248 placenta 5' read
CN281650.1 embryonic tissue 5' read P
CN284141.1 embryonic tissue 5' read
CN293423.1 embryonic tissue 5' read
AW960474.1 uncharacterized tissue
CN430775.1 embryonic tissue 5' read
AW977659.1 uncharacterized tissue
AW979328.1 uncharacterized tissue
BE048938.1 Clone IMAGE:3132455 kidney 3' read A
BE173637.1 thyroid
CR743808.1 Clone IMAGp998N061825_;_IMAGE:743237 testis 5' read
BP202419.1 Clone AMR08349 brain 5' read
BP204293.1 Clone CAS01950 vascular 5' read
BP206242.1 Clone CAS07653 vascular 5' read
BP207072.1 Clone CAS09581 vascular 5' read
BP221495.1 Clone COL09129 intestine 5' read
BP221791.1 Clone COR00103 skin 5' read
BP223338.1 Clone ColF0998 intestine 5' read P
BP240733.1 Clone HEP12847 liver 5' read
BP250768.1 Clone HPR05052 brain 5' read
BP314528.1 Clone OFR06439 mammary gland 5' read P
BP327882.1 Clone PRS08328 prostate 5' read
BP346357.1 Clone SYN09391 connective tissue 5' read P
BP337839.1 Clone SMR09414 vascular 5' read
BP379100.1 Clone WMD04621 uterus 5' read P
BE295273.1 Clone IMAGE:3531102 muscle 5' read
BE296595.1 Clone IMAGE:3529057 muscle 5' read
BE466935.1 Clone IMAGE:3212233 lung 3' read
BE540895.1 Clone IMAGE:3449595 placenta 5' read
BE614032.1 Clone IMAGE:3905703 uterus 5' read
CX787492.1 Clone IMAGE:7483720 embryonic tissue 5' read
BE737866.1 Clone IMAGE:3839833 brain 5' read
BE738328.1 Clone IMAGE:3839833 brain 3' read
BE815153.1 mammary gland P
BE825608.1 lung
BE883242.1 Clone IMAGE:3910456 uterus 5' read
DR005632.1 Clone TC117088 prostate 5' read P
BE855881.1 Clone IMAGE:3305640 brain 3' read P
AV703543.2 Clone ADBDBF12 adrenal gland 5' read
AV708111.1 Clone ADCAAC10 adrenal gland 5' read
BF035537.1 Clone IMAGE:3861194 ovary 5' read
CR985923.1 Clone RZPDp9017F1641 uncharacterized tissue 5' read P
BF112241.1 Clone IMAGE:3524080 mixed 3' read
AU134874.1 Clone PLACE1000722 placenta 5' read P
BF337289.1 Clone IMAGE:4182637 brain 5' read
BF672434.1 Clone IMAGE:4291842 muscle 5' read
DA316093.1 Clone BRHIP3006815 brain 5' read P
BF691938.1 Clone IMAGE:4333886 skin 5' read
DA103876.1 Clone BRACE3017024 brain 5' read P
BF694304.1 Clone IMAGE:4247098 muscle 5' read P
DA336622.1 Clone BRHIP3037217 brain 5' read
DA233671.1 Clone BRAWH3029648 brain 5' read P
DA122492.1 Clone BRACE3044033 brain 5' read
DA392522.1 Clone BRTHA2030579 brain 5' read
DA618208.1 Clone IMR322018106 brain 5' read
DA658950.1 Clone MESAN2015435 kidney 5' read
DA553632.1 Clone HCHON2003486 connective tissue 5' read P
DA548396.1 Clone HCASM2006718 vascular 5' read
DA561749.1 Clone HEART2002960 heart 5' read
H70547.1 Clone IMAGE:212596 mixed 5' read
AW604884.1 intestine
DA490723.1 Clone FCBBF3002021 brain 5' read
DA412705.1 Clone BRTHA3020368 brain 5' read
DA564518.1 Clone HEART2006762 heart 5' read
DA408497.1 Clone BRTHA3014536 brain 5' read P
DA572193.1 Clone HEMBB1000715 mixed 5' read
DA572314.1 Clone HEMBB1000952 mixed 5' read
DA989692.1 Clone SYNOV4001065 connective tissue 5' read P
BF431088.1 Clone IMAGE:3573384 kidney 3' read
DA855728.1 Clone PLACE7006521 placenta 5' read P
DA928796.1 Clone SMINT2016354 intestine 5' read
DA941371.1 Clone SPLEN2015563 spleen 5' read
DA857489.1 Clone PLACE7008799 placenta 5' read
BF541961.1 Clone IMAGE:4067537 kidney 5' read
BF476184.1 Clone IMAGE:3257930 kidney 3' read
DA715243.1 Clone NT2RI2022468 5' read
BF512020.1 Clone IMAGE:3088610 uncharacterized tissue 3' read A
BF512021.1 Clone IMAGE:3088612 uncharacterized tissue 3' read A
BF512022.1 Clone IMAGE:3088614 uncharacterized tissue 3' read A
BF512025.1 Clone IMAGE:3088620 uncharacterized tissue 3' read A
BF512027.1 Clone IMAGE:3088624 uncharacterized tissue 3' read A
BF512028.1 Clone IMAGE:3088626 uncharacterized tissue 3' read A
BF512030.1 Clone IMAGE:3088630 uncharacterized tissue 3' read A
BF512032.1 Clone IMAGE:3088658 uncharacterized tissue 3' read A
BF512033.1 Clone IMAGE:3088660 uncharacterized tissue 3' read A
BF512034.1 Clone IMAGE:3088662 uncharacterized tissue 3' read A
BF512035.1 Clone IMAGE:3088664 uncharacterized tissue 3' read A
BF512036.1 Clone IMAGE:3088666 uncharacterized tissue 3' read A
BF512037.1 Clone IMAGE:3088668 uncharacterized tissue 3' read A
BF512043.1 Clone IMAGE:3088708 uncharacterized tissue 3' read A
H81759.1 Clone IMAGE:249232 skin 5' read
H81760.1 Clone IMAGE:249232 skin 3' read
DA723799.1 Clone NT2RI3005003 testis 5' read P
DB106038.1 Clone THYMU2007135 thymus 5' read
DB074714.1 Clone TESTI4018383 testis 5' read P
DB336850.1 Clone TESTI2012052 testis 3' read A
DB231495.1 Clone TRACH3025114 trachea 5' read P
DB268556.1 Clone UTERU2029169 uterus 5' read
BF748864.1 mammary gland
DB324149.1 Clone NT2RI2022468 3' read
DB318826.1 Clone HEART2006762 heart 3' read
DB359169.1 Clone HEMBB1000715 mixed 3' read
DB359309.1 Clone HEMBB1000952 mixed 3' read
DB065201.1 Clone TESTI4006200 testis 5' read P
DB372717.1 Clone PLACE1000722 placenta 3' read A
DB333201.1 Clone SPLEN2015563 spleen 3' read
DB066531.1 Clone TESTI4007896 testis 5' read
H87282.1 Clone IMAGE:223693 eye 3' read
BF811510.1 intestine
DW450302.1 liver
BF974636.1 Clone IMAGE:4334536 tonsil 5' read P
BF939285.1 Clone IMAGE:3410404 prostate 3' read
N20591.1 Clone IMAGE:264131 skin 3' read
F15813.2 Clone NOTAVAIL00284 muscle
F16318.2 Clone NOTAVAIL00805 muscle
BG179431.1 Clone IMAGE:4431956 prostate 5' read
BG055104.1 Clone IMAGE:3432330 prostate 3' read
N24334.1 Clone IMAGE:262702 skin 5' read
DB525501.1 Clone H013088H04 testis 3' read
DB460058.1 Clone H013088H04 testis 5' read
N28985.1 Clone IMAGE:264131 skin 5' read
EC495412.1 prostate
EC502058.1 prostate
EC502106.1 prostate
EC518045.1 prostate
EC528935.1 prostate
BG387359.1 Clone IMAGE:4584436 intestine 5' read
BG402734.1 Clone IMAGE:4525530 bladder 5' read
BG500660.1 Clone IMAGE:4669380 prostate 5' read
BG620237.1 Clone IMAGE:4732178 placenta 5' read
BG623849.1 Clone IMAGE:4770671 placenta 5' read
BI086407.1 Clone IMAGE:4991388 placenta 5' read
BI054461.1 placenta
N75467.1 Clone IMAGE:299141 lung 3' read
N77917.1 Clone IMAGE:300081 lung 3' read
ES313223.1 skin
ES313983.1 skin
AL599377.1 Clone DKFZp313J1229 uncharacterized tissue 5' read
AL600335.1 Clone DKFZp313D0133 uncharacterized tissue 5' read
BI460124.1 Clone IMAGE:5267398 testis 5' read
BI754195.1 Clone IMAGE:5195876 brain 5' read
W05276.1 Clone IMAGE:299141 lung 5' read
W07084.1 Clone IMAGE:300081 lung 5' read
W15523.1 Clone IMAGE:320176 parathyroid 3' read
W31606.1 Clone IMAGE:320176 parathyroid 5' read
BM550578.1 Clone IMAGE:5549282 skin 5' read A
W44795.1 Clone IMAGE:320855 parathyroid 3' read
W45459.1 Clone IMAGE:328936 pancreas 3' read
AL700463.1 Clone DKFZp686P22118 muscle 5' read
AL706046.1 Clone DKFZp686K2139 muscle 5' read
AL706056.1 Clone DKFZp686L2139 muscle 5' read
AL708697.1 Clone DKFZp686N0153 muscle 5' read
AL711899.1 Clone DKFZp686J1385 muscle 5' read
BQ019397.1 Clone IMAGE:5824522 connective tissue 3' read A
BQ022047.1 Clone UI-1-BB1p-ajx-c-10-0-UI placenta 3' read A
BQ027352.1 Clone IMAGE:3104870 uncharacterized tissue 3' read A
BQ129162.1 Clone IMAGE:6136602 pancreas 3' read A
BQ129168.1 Clone IMAGE:6136642 pancreas 3' read A
BQ129287.1 Clone IMAGE:6136602 pancreas 5' read
BQ129291.1 Clone IMAGE:6136642 pancreas 5' read
BQ186485.1 Clone UI-E-EJ1-ajr-e-04-0-UI eye 5' read A
BQ188535.1 Clone UI-E-EJ1-ajw-l-04-0-UI eye 5' read A
BQ189306.1 Clone UI-E-EJ1-ajv-d-21-0-UI eye 5' read A
BQ214396.1 Clone IMAGE:6066250 skin 5' read A
BQ215398.1 Clone IMAGE:6046751 skin 5' read
BQ309037.1 mammary gland
AA017112.1 Clone IMAGE:360811 eye 5' read
AA017113.1 Clone IMAGE:360811 eye 3' read
BQ436907.1 Clone IMAGE:6065625 skin 5' read
BQ440705.1 Clone IMAGE:6158398 skin 5' read
BQ581912.1 Clone IMAGE:6029701 pancreas 5' read
AA035348.1 Clone IMAGE:471502 uterus 3' read
BQ777040.1 Clone IMAGE:6032773 pancreas 5' read
BG120512.1 Clone IMAGE:4441831 liver 5' read
BM738829.1 Clone S3SNU16-1-H09 ascites 5' read A
BQ879883.1 Clone IMAGE:6182719 ganglia 5' read
BQ882369.1 Clone IMAGE:6195593 nerve 5' read
BU075509.1 Clone IMAGE: pancreas 5' read
AA094618.1 heart 5' read
FN083936.1 Clone 073690_1372_2833
FN058268.1 Clone 016451_3057_0777
FN056208.1 Clone 013989_3962_1595
BU570251.1 Clone IMAGE:6618449 testis 5' read
BU587963.1 Clone IMAGE:6386030 mixed 5' read A
AA166968.1 Clone IMAGE:593786 ovary 3' read
AA167046.1 Clone IMAGE:593786 ovary 5' read
BU618843.1 Clone UI-H-FH1-bfl-m-17-0-UI bone 3' read A
AA193251.1 Clone IMAGE:665766 mixed 5' read
T69969.1 Clone IMAGE:81119 lung 5' read
BU675199.1 Clone UI-CF-DU1-aaf-f-19-0-UI lung 3' read A
AA228908.1 Clone IMAGE:1010168 prostate
AA228890.1 Clone IMAGE:1010168 prostate
BU753617.1 Clone UI-1-BB1p-ajw-b-05-0-UI placenta 3' read A
AA234767.1 Clone IMAGE:687315 mixed 3' read
AA253234.1 Clone IMAGE:667131 mixed 5' read
CA312167.1 Clone UI-CF-FN0-afj-d-14-0-UI lung 3' read A
CA389827.1 Clone cs103a11 eye 5' read
CA405711.1 adipose tissue 5' read
CA439687.1 Clone UI-H-DT1-awe-i-13-0-UI connective tissue 3' read A
CA441583.1 Clone UI-H-DP0-avd-j-01-0-UI connective tissue 3' read A
CA454629.1 Clone IMAGE:6720714 mixed 5' read P
AA328243.1 embryonic tissue 5' read
AA293528.1 Clone IMAGE:726194 ovary 5' read
AA293529.1 Clone IMAGE:726194 ovary 3' read A
CA951940.1 Clone IMAGE: pancreas 3' read
CA952192.1 Clone IMAGE: pancreas 5' read
AA401881.1 Clone IMAGE:758563 embryonic tissue 5' read
AA405122.1 Clone IMAGE:742851 testis 5' read
AA406184.1 Clone IMAGE:742851 testis 3' read
AA421982.1 Clone IMAGE:754543 mixed 5' read
AA422119.1 Clone IMAGE:754816 mixed 5' read P
AA425089.1 Clone IMAGE:768552 mixed 3' read P
AA429292.1 Clone IMAGE:768552 mixed 5' read P
AA484855.1 Clone IMAGE:910635 bone
AA477758.1 Clone IMAGE:739890 ovary 3' read A
AA477867.1 Clone IMAGE:739890 ovary 5' read
AA588008.1 Clone IMAGE:1075726 intestine 3' read
AA629229.1 Clone IMAGE:743676 testis 3' read A
AA632324.1 Clone IMAGE:1131011 mammary gland 3' read
AA652217.1 Clone IMAGE:1188332 prostate 3' read A
AA657639.1 Clone IMAGE:1215402 muscle P
C75056.1 Clone hbc7082 pancreas
AA661704.1 Clone IMAGE:1217698 muscle P
AA704789.1 Clone IMAGE:452325 mixed 3' read
AA732420.1 Clone IMAGE:1302918 lymph node 3' read A
AA732605.1 Clone IMAGE:1302252 lymph node 3' read A
AA747766.1 Clone IMAGE:1268335 bone A
AA809894.1 Clone IMAGE:1319772 lymph node 3' read
AA810753.1 Clone IMAGE:1318747 lymph node 3' read
AA854200.1 Clone IMAGE:1401254 parathyroid 3' read A
AA856549.1 Clone IMAGE:1411698 prostate 3' read
AA856550.1 Clone IMAGE:1411700 prostate 3' read
AA857050.1 Clone IMAGE:1410316 prostate 3' read A
AA883954.1 Clone IMAGE:1467654 mixed 3' read
AA884047.1 Clone IMAGE:1468344 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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