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UGID:221059     UniGene Hs.408461     Homo sapiens (human)   DDX6
DEAD (Asp-Glu-Ala-Asp) box helicase 6 (DDX6)

Human protein-coding gene DDX6. Represented by 272 ESTs from 177 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 221059 - Hs.408461]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001370626.1 PREDICTED: probable ATP-dependent RNA helicase DDX6 M. domestica 100.0 482
XP_003910842.1 PREDICTED: probable ATP-dependent RNA helicase DDX6 P. anubis 100.0 482
XP_508798.2 PREDICTED: probable ATP-dependent RNA helicase DDX6 isoform 2 P. troglodytes 100.0 482
NP_004388.2 DDX6 gene product H. sapiens 100.0 482
XP_849975.1 PREDICTED: probable ATP-dependent RNA helicase DDX6 isoform 2 C. lupus familiaris 100.0 482
XP_001503067.1 PREDICTED: probable ATP-dependent RNA helicase DDX6 E. caballus 100.0 482
NP_001137339.1 probable ATP-dependent RNA helicase DDX6 B. taurus 100.0 482
XP_001516184.2 PREDICTED: probable ATP-dependent RNA helicase DDX6 O. anatinus 100.0 423
XP_003129962.1 PREDICTED: probable ATP-dependent RNA helicase DDX6 isoform 1 S. scrofa 99.8 482
XP_004016131.1 PREDICTED: probable ATP-dependent RNA helicase DDX6 O. aries 99.8 482
XP_002722747.1 PREDICTED: DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 O. cuniculus 99.8 482
XP_003212776.1 PREDICTED: probable ATP-dependent RNA helicase DDX6-like M. gallopavo 99.6 482
NP_851841.2 probable ATP-dependent RNA helicase DDX6 M. musculus 99.4 482
NP_001083721.1 ATP-dependent RNA helicase ddx6 X. laevis 96.7 480
XP_684923.1 PREDICTED: probable ATP-dependent RNA helicase DDX6 isoform 1 D. rerio 93.8 483
NP_723539.1 maternal expression at 31B, isoform B D. melanogaster 79.5 399
XP_001692202.1 cytoplasmic DExD/H-box RNA helicase C. reinhardtii 77.4 399
NP_498646.1 Protein CGH-1 C. elegans 74.5 411
XP_960011.2 hypothetical protein NCU06149 N. crassa 73.8 413
NP_191683.1 DEAD-box ATP-dependent RNA helicase 12 A. thaliana 73.6 439
NP_010121.1 Dhh1p S. cerevisiae 72.5 419
Other hits (2 of 49) [Show all]SpeciesId(%)Len(aa)
XP_002808135.1 PREDICTED: LOW QUALITY PROTEIN: probable ATP-dependent RNA helicase DDX6-like M. mulatta 99.4 485
NP_001102762.1 probable ATP-dependent RNA helicase DDX6 R. norvegicus 99.4 482

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; stomach; pituitary gland; blood; embryonic tissue; placenta; mixed; ovary; mammary gland; pharynx; thymus; lung; uncharacterized tissue; pancreas; uterus; prostate; intestine; connective tissue; mouth; larynx; adrenal gland; testis; tonsil; vascular; trachea; bladder; skin; parathyroid; bone marrow; eye; bone; kidney; lymph node; esophagus; heart; nerve; liver; muscle; salivary gland; spleen; ascites
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q23.3
UniSTS entry: Chr 12 RH65211
UniSTS entry: Chr 11 SHGC-53933
UniSTS entry: Chr 11 SGC30501 [Map Viewer]
UniSTS entry: Ddx6
UniSTS entry: Chr 11 SGC31470 [Map Viewer]
UniSTS entry: Chr 11 DDX6 [Map Viewer]
UniSTS entry: Chr 11 GDB:197860
UniSTS entry: Ddx6
UniSTS entry: Chr 11 D11S4963
UniSTS entry: Chr 11 SHGC-37225 [Map Viewer]
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

NM_004397.4 Homo sapiens DEAD (Asp-Glu-Ala-Asp) box helicase 6 (DDX6), transcript variant 1, mRNA PA
BC065007.1 Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 6, mRNA (cDNA clone MGC:74611 IMAGE:6163439), complete cds PA
AK021715.1 Homo sapiens cDNA FLJ11653 fis, clone HEMBA1004538 A
D17532.1 Homo sapiens mRNA for RCK, complete cds P
AK313244.1 Homo sapiens cDNA, FLJ93750, Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 (DDX6), mRNA P
AK093657.1 Homo sapiens cDNA FLJ36338 fis, clone THYMU2006357, highly similar to PROBABLE ATP-DEPENDENT RNA HELICASE P54 P
BC026228.1 Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 6, mRNA (cDNA clone IMAGE:4701626), with apparent retained intron A
Z11685.1 H.sapiens mRNA for RNA helicase P
NM_001257191.1 Homo sapiens DEAD (Asp-Glu-Ala-Asp) box helicase 6 (DDX6), transcript variant 2, mRNA PA
BC039826.1 Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 6, mRNA (cDNA clone IMAGE:5582799), complete cds PA

EST sequences (272)

AI023800.1 Clone IMAGE:1655727 mixed 3' read
AI023939.1 Clone IMAGE:1650583 parathyroid 3' read A
AI082658.1 Clone IMAGE:1660596 mixed 3' read
AI140333.1 Clone IMAGE:1693192 heart 3' read A
CB052180.1 Clone IMAGE:3290111 uncharacterized tissue 3' read A
CB052181.1 Clone IMAGE:3290111 uncharacterized tissue 5' read
BX093577.1 Clone IMAGp998M134214_;_IMAGE:1660596 mixed
AI186870.1 Clone IMAGE:1741113 lung 3' read A
AI189017.1 Clone IMAGE:1724987 placenta 3' read A
AI252635.1 Clone IMAGE:1977080 brain 3' read A
AI265778.1 Clone IMAGE:2006525 ovary 3' read A
CB114281.1 Clone L4SNU368-25-F10 liver 5' read
CB128099.1 Clone L11SNU354-20-H05 liver 5' read
AI282746.1 Clone IMAGE:1960658 esophagus 3' read A
AI292106.1 Clone IMAGE:1895329 lung 3' read
AI338713.1 Clone IMAGE:1951055 lung 3' read A
AI347567.1 Clone IMAGE:1916626 kidney 3' read A
AI351662.1 Clone IMAGE:1940224 embryonic tissue 3' read
AI418561.1 Clone IMAGE:2110929 mixed 3' read
AI434678.1 Clone IMAGE:2132498 lymph node 3' read A
AI523557.1 Clone IMAGE:2117678 uncharacterized tissue 3' read
AI523572.1 Clone IMAGE:2117700 uncharacterized tissue 3' read A
AI537100.1 Clone IMAGE:2179139 uterus 3' read A
AI539409.1 Clone IMAGE:2089725 mixed 3' read
AI564830.1 Clone IMAGE:2169850 brain 3' read A
AI566453.1 Clone IMAGE:2222682 pancreas 3' read
AI400856.1 Clone IMAGE:2119285 prostate 3' read A
AI678292.1 Clone IMAGE:2257339 stomach 3' read A
AI784312.1 Clone IMAGE:2049407 embryonic tissue 3' read
AI803390.1 Clone IMAGE:2067294 embryonic tissue 3' read A
CB409500.1 Clone IMAGE:5796132 bone 5' read
CB409832.1 Clone IMAGE:5796594 bone 3' read
CB409833.1 Clone IMAGE:5796594 bone 5' read
AI826271.1 Clone IMAGE:2417205 prostate 3' read A
AI400911.1 Clone IMAGE:2119831 prostate 3' read
CD000872.1 Clone IMAGE:30321386 mixed 5' read
BX391529.2 Clone CS0DC020YP23 uncharacterized tissue 3' read P
BX329622.2 Clone CS0DC020YP23 uncharacterized tissue 3' read P
BX375980.2 Clone CS0DC020YP23 uncharacterized tissue 3' read PA
BX415284.2 Clone CS0CAP005YM10 thymus 5' read
CD238276.1 pituitary gland
AW015315.1 Clone IMAGE:2710005 uncharacterized tissue 3' read A
CD640529.1 Clone IMAGE:30417809 blood 5' read A
CD640721.1 Clone IMAGE:30414805 blood 5' read A
CD694848.1 pharynx
CD694881.1 pharynx P
CD709688.1 pharynx
CD709857.1 pharynx
CD742755.1 Clone UI-H-FT2-bjl-l-19-0-UI lung 3' read A
F07407.1 Clone c-24g05 brain
F03643.1 Clone c-24g05 brain 3' read
CF137516.1 Clone IMAGE:3092234 lymph node 5' read P
AW139782.1 Clone IMAGE:2718941 mixed 3' read A
AW149702.1 Clone IMAGE:2620626 brain 3' read
AJ574617.1 Clone HSPD48646 muscle A
CF456359.1 Clone IMAGE:30515276 nerve 5' read
CF528439.1 Clone UI-1-BC1-aix-b-04-0-UI placenta 3' read A
AI908959.1 mammary gland
AW236404.1 Clone IMAGE:2704088 uterus 3' read A
AW276906.1 Clone IMAGE:2744441 ovary 3' read
AW351994.1 larynx
AW351995.1 larynx
AW390291.1 stomach
AW451270.1 Clone IMAGE:2736805 uncharacterized tissue 3' read A
AW750314.1 mammary gland
AW894769.1 brain
AW947938.1 blood P
AW947941.1 blood
CN269660.1 embryonic tissue 5' read
CN272198.1 embryonic tissue 5' read A
CN282637.1 embryonic tissue 5' read P
AW956253.1 uncharacterized tissue
CN360075.1 embryonic tissue 5' read
CN360076.1 embryonic tissue 5' read
CN360077.1 embryonic tissue 5' read
CN360078.1 embryonic tissue 5' read
CN360073.1 embryonic tissue 5' read
CN360072.1 embryonic tissue 5' read
CN360074.1 embryonic tissue 5' read
AW972709.1 uncharacterized tissue
AW992898.1 mammary gland
AW993433.1 mammary gland
AW993451.1 mammary gland
AW993472.1 mammary gland
BE075105.1 mammary gland
BE077137.1 mammary gland
BE218820.1 Clone IMAGE:3176339 lung 3' read
BE242871.1 Clone TCAAP2362 bone marrow
BE242957.1 Clone TCAAP2362 bone marrow
BE243679.1 Clone TCBAP1368 lymph node
BE244078.1 Clone TCBAP1368 lymph node
BP228901.1 Clone FBR01295 brain 5' read P
BP229747.1 Clone FBR04381 brain 5' read P
BP249307.1 Clone HKR13162 kidney 5' read P
BP236072.1 Clone HCR06782 vascular 5' read P
BP236847.1 Clone HCR08634 vascular 5' read P
BP314256.1 Clone OFR05683 mammary gland 5' read P
BP314906.1 Clone OFR07375 mammary gland 5' read P
BP314954.1 Clone OFR07474 mammary gland 5' read
BP320687.1 Clone PLR03489 placenta 5' read
BP327151.1 Clone PRS05820 prostate 5' read
BP351026.1 Clone T3R03007 esophagus 5' read P
BP355911.1 Clone T7R08131 esophagus 5' read P
BP361144.1 Clone THR03969 brain 5' read P
BP362051.1 Clone THR07191 brain 5' read P
BP363378.1 Clone TIR01356 lung 5' read
BP363379.1 Clone TIR01357 lung 5' read
BP276641.1 Clone KDN06909 kidney 5' read
BP308251.1 Clone NRB04447 brain 5' read
BE535847.1 Clone IMAGE:3447154 placenta 5' read P
BE539365.1 Clone IMAGE:3451648 placenta 5' read
BE703543.1 brain
BE714476.1 pharynx
BE767329.1 brain
BE767335.1 brain
BE831166.1 blood
D59720.1 Clone GEN-060E09 brain 5' read
DN991699.1 Clone TC105608 brain 5' read
DN997510.1 Clone TC117398 mammary gland 5' read
BE928097.1 intestine
BE930110.1 placenta
BE934709.1 larynx
R95093.1 Clone IMAGE:198622 mixed 5' read
BF035011.1 Clone IMAGE:3862702 ovary 5' read
BF085676.1 placenta
BF085678.1 placenta
BF086208.1 placenta
BF129093.1 Clone IMAGE:4054474 tonsil 5' read
DN918142.1 Clone MCF7_RNA_L_24_H01 mammary gland
DN918143.1 Clone MCF7_RNA_L_24_H01 mammary gland
DA273300.1 Clone BRCAN2028385 brain 5' read P
DA012503.1 Clone ADRGL2004782 adrenal gland 5' read P
BF675246.1 Clone IMAGE:4274780 prostate 5' read
BF676625.1 Clone IMAGE:4250467 prostate 5' read
DA033108.1 Clone ASTRO2018000 brain 5' read
BF855283.1 prostate
DA655012.1 Clone MESAN2010327 kidney 5' read P
DA442032.1 Clone CTONG2011243 mouth 5' read P
DA482515.1 Clone ERLTF2002139 bone marrow 5' read P
DA444047.1 Clone CTONG2014085 mouth 5' read
DA556842.1 Clone HCHON2007374 connective tissue 5' read P
AV718351.1 Clone FHTBAAE04 brain 5' read
BF063449.1 Clone IMAGE:3335607 mammary gland 3' read
DA382283.1 Clone BRTHA2016149 brain 5' read
AU145331.1 Clone HEMBA1004538 embryonic tissue 3' read A
DA993470.1 Clone SYNOV4005974 connective tissue 5' read
DA781609.1 Clone OCBBF2017192 brain 5' read
DA777805.1 Clone OCBBF2012299 brain 5' read P
DA712260.1 Clone NT2RI2018438 5' read P
DB016049.1 Clone TESOP2005259 esophagus 5' read P
DA864063.1 Clone PLACE7017681 placenta 5' read P
DA754310.1 Clone NT2RP8000261 testis 5' read P
DA800442.1 Clone OCBBF3004406 brain 5' read
DB342856.1 Clone THYMU2006357 thymus 3' read
DB236481.1 Clone TRACH3031794 trachea 5' read
DB277234.1 Clone UTERU3002833 uterus 5' read
DB211299.1 Clone TRACH2024701 trachea 5' read P
DB291678.1 Clone UTERU3022135 uterus 5' read P
DB207061.1 Clone TRACH2019584 trachea 5' read P
DB105533.1 Clone THYMU2006357 thymus 5' read
BF802730.1 intestine
BF803744.1 intestine
BF810127.1 intestine A
DW424206.1 liver P
BF816403.1 intestine
BF834827.1 larynx P
BG111480.1 Clone IMAGE:4370421 bone 5' read A
BG004830.1 placenta
BF968462.1 Clone IMAGE:4359268 adrenal gland 5' read
BF971467.1 Clone IMAGE:4360814 adrenal gland 5' read
BF888931.1 testis
BF911089.1 uterus
BF915822.1 uterus
BG166537.1 Clone IMAGE:4448150 kidney 5' read
BG179882.1 Clone IMAGE:4430353 prostate 5' read
DB482839.1 Clone H023095D11 brain 5' read
BG259835.1 Clone IMAGE:4479812 bladder 5' read
BG338266.1 Clone IMAGE:4553598 uterus 5' read A
N41434.1 Clone IMAGE:259824 placenta 5' read
BG397536.1 Clone IMAGE:4565392 tonsil 5' read
BG546189.1 Clone IMAGE:4701626 lung 5' read
BG538927.1 Clone IMAGE:4693074 lung 5' read
BG195931.1 connective tissue
N55367.1 Clone IMAGE:245904 mixed 3' read
BG756236.1 Clone IMAGE:4853987 tonsil 5' read
BI094223.1 Clone IMAGE:5001217 placenta 5' read
N70471.1 Clone IMAGE:298291 lung 3' read A
N70473.1 Clone IMAGE:298295 lung 3' read A
BI038190.1 brain
BI039215.1 brain
BI039766.1 brain
N72861.1 Clone IMAGE:291487 skin 3' read A
N77373.1 Clone IMAGE:245904 mixed 5' read
EL735105.1 mixed 5' read P
BG722018.1 Clone IMAGE:4830863 testis 5' read P
N91018.1 Clone IMAGE:306112 parathyroid 3' read A
BI601100.1 Clone IMAGE:5301190 brain 5' read P
BI544556.1 Clone IMAGE:5284199 brain 5' read
W03083.1 Clone IMAGE:291487 skin 5' read
W03834.1 Clone IMAGE:298291 lung 5' read
BM009751.1 Clone IMAGE:5443895 skin 5' read
BM012472.1 Clone IMAGE:5459419 brain 5' read P
BM013673.1 Clone IMAGE:5415425 mammary gland 5' read
W20147.1 Clone IMAGE:306112 parathyroid 5' read
BM471332.1 Clone IMAGE:5517778 uterus 5' read
BM663654.1 Clone UI-E-CK0-aau-e-09-0-UI eye 3' read A
BM679397.1 Clone UI-E-EO0-ahz-j-02-0-UI eye 3' read A
BM686008.1 Clone UI-E-CK0-aau-e-09-0-UI eye 5' read
W45060.1 Clone IMAGE:322842 skin 5' read
W45070.1 Clone IMAGE:322842 skin 3' read A
BM696691.1 Clone UI-E-DW0-agk-f-19-0-UI eye 5' read
BM716423.1 Clone UI-E-DW0-agk-f-19-0-UI eye 5' read
W48640.1 Clone IMAGE:325286 skin 3' read A
BM720697.1 Clone UI-E-EO0-ahz-j-02-0-UI eye 5' read
W51956.1 Clone IMAGE:325286 skin 5' read
BM728565.1 Clone UI-E-EJ0-aiu-d-21-0-UI eye 5' read
BM746057.1 Clone S4SNU1-11-A03 ascites 5' read A
BM905603.1 Clone IMAGE:5582799 uncharacterized tissue 5' read P
BM918484.1 Clone IMAGE:5747433 mixed 5' read P
BM972001.1 Clone UI-CF-EC1-abo-d-18-0-UI lung 3' read A
BM973907.1 Clone UI-CF-EC1-abz-e-03-0-UI lung 3' read A
AL697132.1 Clone DKFZp686O24101 muscle 5' read
BQ017952.1 Clone IMAGE:5823231 connective tissue 3' read A
BQ311151.1 mammary gland P
BQ365311.1 placenta P
BQ379346.1 uterus P
BQ430873.1 Clone IMAGE:6045022 uncharacterized tissue 5' read P
BQ438803.1 Clone IMAGE:6053311 pancreas 5' read A
BQ447869.1 Clone UI-H-EU1-bag-m-15-0-UI connective tissue 3' read A
BQ636595.1 Clone hd11h01 eye 5' read
BQ673578.1 Clone IMAGE:6256930 salivary gland 5' read
AA039299.1 Clone IMAGE:376029 heart 5' read
AA039300.1 Clone IMAGE:376029 heart 3' read A
BQ707967.1 Clone IMAGE:6278527 spleen 5' read P
BG116794.1 Clone IMAGE:4423339 intestine 5' read
AA046006.1 Clone IMAGE:509828 intestine 5' read
AA046007.1 Clone IMAGE:509828 intestine 3' read A
BU429666.1 Clone IMAGE:3064583 lymph node 5' read P
BU161614.1 Clone IMAGE:6163439 skin 5' read
BU532618.1 Clone IMAGE:6558409 mixed 5' read A
FN116668.1 Clone 162671_1129_2294
FN092485.1 Clone 097504_0670_2047
BU594364.1 Clone IMAGE:6449820 mixed 5' read
BU622820.1 Clone UI-H-FG1-bgf-m-16-0-UI bone 3' read A
BU623707.1 Clone UI-H-FG1-bgi-a-21-0-UI bone 3' read A
BU624894.1 Clone UI-H-FG1-bgl-e-04-0-UI bone 3' read A
BU625208.1 Clone UI-H-FG1-bgm-a-08-0-UI bone 3' read A
GW493501.1 Clone dP1N1-E3 P
BU686744.1 Clone UI-CF-DU1-adl-k-16-0-UI lung 3' read A
BU735206.1 Clone UI-E-DW0-agk-f-19-0-UI eye 3' read A
BU742251.1 Clone UI-E-EO1-aiu-d-21-0-UI eye 3' read A
BU899190.1 Clone IMAGE:6278748 spleen 5' read P
BU902635.1 Clone IMAGE:6526458 uterus 5' read
BU933791.1 Clone IMAGE:6698986 mixed 5' read P
BU939935.1 Clone IMAGE:6708645 mixed 5' read P
HY238338.1 Clone H04D180E10 testis P
CA423151.1 Clone UI-H-FE1-bdz-h-04-0-UI bone 3' read A
CA436093.1 Clone UI-H-DT0-atz-o-19-0-UI connective tissue 3' read A
CA442043.1 Clone UI-H-DH1-axi-o-01-0-UI connective tissue 3' read A
AA454634.1 Clone IMAGE:811880 mixed 3' read
AA456246.1 Clone IMAGE:811880 mixed 5' read
AA523483.1 Clone IMAGE:981919 bone
AA670205.1 Clone IMAGE:878647 brain 3' read A
AA687988.1 Clone IMAGE:1233731 lymph node 3' read
AA702981.1 Clone IMAGE:447182 mixed 3' read
R01532.1 Clone IMAGE:123943 mixed 5' read
AA704321.1 Clone IMAGE:451051 mixed 3' read
AA730229.1 Clone IMAGE:1302340 lymph node 3' read
AA694540.1 Clone 1239635 parathyroid 3' read A
AA865492.1 Clone IMAGE:1470075 uncharacterized tissue 3' read A
AA865583.1 Clone IMAGE:1470176 uncharacterized tissue 3' read
AA865584.1 Clone IMAGE:1470178 uncharacterized tissue 3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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