> Methenyltetrahydrofolate synthetase domain containing (MTHFSD)
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UGID:192554     UniGene Hs.343627     Homo sapiens (human)   MTHFSD Order cDNA clone, Links
Methenyltetrahydrofolate synthetase domain containing (MTHFSD)

Human protein-coding gene MTHFSD. Represented by 192 ESTs from 104 cDNA libraries. Corresponds to 7 reference sequences (different isoforms). [UniGene 192554 - Hs.343627]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001152849.1 MTHFSD gene product H. sapiens 100.0 382
NP_001159954.1 Mthfsd gene product M. musculus 86.0 371
NP_001086453.1 methenyltetrahydrofolate synthase domain-containing protein X. laevis 74.0 385
NP_001038564.1 mthfsd gene product D. rerio 64.3 381
NP_565139.1 5-formyltetrahydrofolate cyclo-ligase A. thaliana 54.4 252
XP_001693876.1 predicted 5-formyltetrahydrofolate cycloligase C. reinhardtii 52.1 288
Other hits (2 of 33) [Show all]SpeciesId(%)Len(aa)
XP_001156018.2 PREDICTED: methenyltetrahydrofolate synthase domain-containing protein isoform 2 P. troglodytes 99.2 382
XP_003917325.1 PREDICTED: methenyltetrahydrofolate synthase domain-containing protein isoform 1 P. anubis 97.4 381

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; pancreas; cervix; skin; bone marrow; uncharacterized tissue; mixed; placenta; embryonic tissue; ovary; lung; blood; spleen; connective tissue; vascular; thyroid; lymph; thymus; lymph node; esophagus; intestine; heart; kidney; prostate; mouth; uterus; stomach; mammary gland; ascites; muscle; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16q24.1
UniSTS entry: Chr 16 SHGC-60741 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

AK023060.1 Homo sapiens cDNA FLJ12998 fis, clone NT2RP3000267 P
AK023955.1 Homo sapiens cDNA FLJ13893 fis, clone THYRO1001661 P
BC112059.1 Homo sapiens methenyltetrahydrofolate synthetase domain containing, mRNA (cDNA clone MGC:138264 IMAGE:8327527), complete cds P
BC112057.1 Homo sapiens methenyltetrahydrofolate synthetase domain containing, mRNA (cDNA clone MGC:138262 IMAGE:8327525), complete cds P
NM_022764.2 Homo sapiens methenyltetrahydrofolate synthetase domain containing (MTHFSD), transcript variant 3, mRNA PA
BC013911.2 Homo sapiens methenyltetrahydrofolate synthetase domain containing, mRNA (cDNA clone IMAGE:4064921) PA
AK096836.1 Homo sapiens cDNA FLJ39517 fis, clone PUAEN2000394 P
AK297726.1 Homo sapiens cDNA FLJ61139 complete cds P
BC143707.1 Homo sapiens methenyltetrahydrofolate synthetase domain containing, mRNA (cDNA clone MGC:177238 IMAGE:9052221), complete cds P
BC143703.1 Homo sapiens cDNA clone IMAGE:9052217, with apparent retained intron P
BC143702.1 Homo sapiens cDNA clone MGC:177233 IMAGE:9052216, complete cds P
BC143705.1 Homo sapiens cDNA clone IMAGE:9052219 P
BC143704.1 Homo sapiens cDNA clone IMAGE:9052218 P
NM_001159380.1 Homo sapiens methenyltetrahydrofolate synthetase domain containing (MTHFSD), transcript variant 5, mRNA PA
NM_001159379.1 Homo sapiens methenyltetrahydrofolate synthetase domain containing (MTHFSD), transcript variant 4, mRNA PA
NM_001159378.1 Homo sapiens methenyltetrahydrofolate synthetase domain containing (MTHFSD), transcript variant 2, mRNA PA
NM_001159377.1 Homo sapiens methenyltetrahydrofolate synthetase domain containing (MTHFSD), transcript variant 1, mRNA PA
NR_027490.1 Homo sapiens methenyltetrahydrofolate synthetase domain containing (MTHFSD), transcript variant 7, non-coding RNA PA
NR_027489.1 Homo sapiens methenyltetrahydrofolate synthetase domain containing (MTHFSD), transcript variant 6, non-coding RNA PA

EST sequences (192)

AA993008.1 Clone IMAGE:1622733 embryonic tissue 3' read
AI122660.1 Clone IMAGE:1693871 heart 3' read
AI128785.1 Clone IMAGE:1691461 heart 3' read A
AI138208.1 Clone IMAGE:1713401 placenta 3' read
AI148729.1 Clone IMAGE:1714461 placenta 3' read
BX115194.1 Clone IMAGp998K10732_;_IMAGE:323457 skin P
BX089124.1 Clone IMAGp998A224355_;_IMAGE:1714461 placenta P
AI219102.1 Clone IMAGE:1759283 placenta 3' read
AI263847.1 Clone IMAGE:1856129 mixed 3' read A
R35419.1 Clone IMAGE:38384 brain 5' read
AI394599.1 Clone IMAGE:2108685 uncharacterized tissue 3' read A
AI472911.1 Clone IMAGE:2147361 mixed 3' read A
T08481.1 Clone HIBBE90 brain 5' read
AI535787.1 prostate 3' read
AI553649.1 Clone IMAGE:2211862 uterus 3' read A
AI569010.1 Clone IMAGE:2214382 lung 3' read A
AI572528.1 Clone IMAGE:2089025 mixed 3' read A
R49216.1 Clone IMAGE:38384 brain 3' read
AI654381.1 Clone IMAGE:2216096 ovary 3' read A
AI655078.1 Clone IMAGE:2309431 uncharacterized tissue 3' read A
AI674146.1 Clone IMAGE:2327536 intestine 3' read A
AI674800.1 Clone IMAGE:2315257 prostate 3' read A
BX385162.2 Clone CS0DL007YO16 uncharacterized tissue 3' read
BX385163.2 Clone CS0DL007YO16 uncharacterized tissue 5' read
AI868507.1 Clone IMAGE:2147428 mixed 3' read A
BX393862.2 Clone CS0DC005YG01 uncharacterized tissue 5' read P
BX372609.2 Clone CS0DC005YG01 uncharacterized tissue 3' read A
BX381636.2 Clone CS0DI068YC16 placenta 5' read P
AI953239.1 Clone IMAGE:2474709 uncharacterized tissue 3' read A
AI983403.1 Clone IMAGE:2520477 intestine 3' read A
AW080771.1 Clone IMAGE:2587884 esophagus 3' read A
AW131350.1 Clone IMAGE:2622605 stomach 3' read A
AW136347.1 Clone IMAGE:2715009 mixed 3' read A
AW139441.1 Clone IMAGE:2717778 mixed 3' read A
CF529587.1 Clone UI-1-BC1p-asy-b-04-0-UI placenta 3' read A
AW207197.1 Clone IMAGE:2721538 mixed 3' read A
AW376120.1 intestine
AW591748.1 Clone IMAGE:2793459 uterus 3' read A
AW592597.1 Clone IMAGE:2934794 mixed 3' read A
AW771206.1 Clone IMAGE:3032258 kidney 3' read A
BX956867.1 Clone DKFZp781K2392 uncharacterized tissue 5' read P
AW862403.1 intestine P
CN277680.1 embryonic tissue 5' read P
CN310283.1 embryonic tissue 5' read P
CN310284.1 embryonic tissue 5' read P
AW960521.1 uncharacterized tissue
CO246231.1 Clone IMAGE:30920821 lung 5' read P
CO248610.1 Clone IMAGE:30923870 lung 5' read P
BE242139.1 Clone TCAAP1421 bone marrow
BE264481.1 Clone IMAGE:3536716 lung 5' read
BE264766.1 Clone IMAGE:3536741 lung 5' read P
BP233080.1 Clone FMR08761 muscle 5' read P
BP363970.1 Clone TIR02928 lung 5' read P
BP366221.1 Clone TIR09455 lung 5' read P
BP282378.1 Clone KMR03987 bone marrow 5' read P
BE351004.1 Clone IMAGE:3147479 kidney 3' read A
CV366082.1 brain
H29616.1 Clone IMAGE:52761 brain 3' read A
BE503474.1 Clone IMAGE:3219175 uncharacterized tissue 3' read A
H29708.1 Clone IMAGE:52761 brain 5' read P
BE545058.1 Clone IMAGE:3464678 cervix 5' read
BE550436.1 Clone IMAGE:3219754 uncharacterized tissue 3' read A
BP396028.1 Clone hbt08183 pancreas 3' read
BE881073.1 Clone IMAGE:3894200 lung 5' read
BE894147.1 Clone IMAGE:3923466 skin 5' read P
BF036541.1 Clone IMAGE:3863432 ovary 5' read P
AU130110.1 Clone NT2RP3000267 testis 5' read P
BF184431.1 Clone IMAGE:4064921 bone marrow 5' read P
DA091065.1 Clone BRACE2046948 brain 5' read
DA269254.1 Clone BRCAN2023331 brain 5' read P
DA290316.1 Clone BRHIP2001621 brain 5' read P
DA064912.1 Clone BRACE2014198 brain 5' read P
DA150625.1 Clone BRAMY2008439 brain 5' read
DA144087.1 Clone BRAMY2000192 brain 5' read P
DA080014.1 Clone BRACE2032999 brain 5' read P
DA435429.1 Clone CTONG2002148 mouth 5' read P
DA402307.1 Clone BRTHA3006008 brain 5' read P
DA665326.1 Clone NB9N42000820 uncharacterized tissue 5' read P
DA659633.1 Clone MESAN2016313 kidney 5' read P
DA476689.1 Clone DFNES2005819 skin 5' read P
AU142038.1 Clone THYRO1001661 thyroid 5' read P
DA677687.1 Clone NETRP2008975 blood 5' read P
DA651421.1 Clone MESAN2005398 kidney 5' read P
DA770430.1 Clone OCBBF2003111 brain 5' read P
DA797523.1 Clone OCBBF3000658 brain 5' read P
AU151516.2 Clone NT2RP2005440 testis 3' read A
AU152132.1 Clone NT2RP3000267 testis 3' read A
DA810494.1 Clone OCBBF3027096 brain 5' read P
DB029536.1 Clone TESTI2012773 testis 5' read P
DA732513.1 Clone NT2RP2000834 testis 5' read P
DA805823.1 Clone OCBBF3021020 brain 5' read P
DA767166.1 Clone NTONG2008632 mouth 5' read P
DA734559.1 Clone NT2RP2005440 testis 5' read P
AU159439.1 Clone THYRO1001661 thyroid 3' read
DA742597.1 Clone NT2RP7006119 testis 5' read P
DA782825.1 Clone OCBBF2018762 brain 5' read P
DA933508.1 Clone SPLEN2003683 spleen 5' read P
DB047230.1 Clone TESTI2035971 testis 5' read P
DA974512.1 Clone SYNOV2004730 connective tissue 5' read
DB016864.1 Clone TESOP2006278 esophagus 5' read P
DA969988.1 Clone STOMA2009056 stomach 5' read P
DA819810.1 Clone PEBLM2008460 blood 5' read P
DA714875.1 Clone NT2RI2021988 5' read P
DA840115.1 Clone PLACE6006886 placenta 5' read P
DA952081.1 Clone SPLEN2029624 spleen 5' read P
DA835069.1 Clone PLACE6000221 placenta 5' read P
DA881098.1 Clone PUAEN2000394 vascular 5' read P
DA881494.1 Clone PUAEN2000875 vascular 5' read P
BF796444.1 Clone IMAGE:4343300 lymph 5' read
DB311570.1 Clone BRTHA2018707 brain 3' read A
DB130879.1 Clone THYMU3000345 thymus 5' read P
DB085711.1 Clone TESTI4033086 testis 5' read P
DB092906.1 Clone TESTI4042683 testis 5' read P
DB167720.1 Clone TKIDN2001245 kidney 5' read P
DB364040.1 Clone NT2RP2000834 testis 3' read A
DB255942.1 Clone UTERU2011496 uterus 5' read P
DB145331.1 Clone THYMU3020202 thymus 5' read P
BG014917.1 placenta P
BG014930.1 placenta
DB517491.1 Clone H013055J21 testis 3' read A
DB519004.1 Clone H013061P19 testis 3' read A
AL522600.3 Clone CS0DB008YH21 uncharacterized tissue 3' read A
AL522601.3 Clone CS0DB008YH21 uncharacterized tissue 5' read P
DB451962.1 Clone H013055J21 testis 5' read P
DB453537.1 Clone H013061P19 testis 5' read P
BG775531.1 Clone IMAGE:4761179 prostate 5' read P
BG775806.1 Clone IMAGE:4761179 prostate 3' read
BG722789.1 Clone IMAGE:4827465 testis 5' read
BI255481.1 Clone IMAGE:5122990 cervix 5' read A
DC301600.1 Clone BNGH42002313 brain 5' read P
DC296482.1 Clone SYNOV4007431 connective tissue 5' read P
DC362004.1 Clone KIDNE2011099 kidney 5' read P
DC349463.1 Clone DFNES2010758 skin 5' read P
DC341405.1 Clone BRTHA2028812 brain 5' read P
DC354398.1 Clone FEHRT2002556 heart 5' read P
DC393306.1 Clone TBAES2009196 mammary gland 5' read P
DC403059.1 Clone TESTI4035865 testis 5' read P
DC331575.1 Clone BRHIP2020767 brain 5' read P
DC390101.1 Clone SPLEN2017305 spleen 5' read P
DC383456.1 Clone PROST2009590 prostate 5' read P
DC373716.1 Clone NTONG2007329 mouth 5' read P
DC355029.1 Clone HCASM2003137 vascular 5' read P
DC329828.1 Clone BRHIP2000036 brain 5' read P
BI668644.1 Clone IMAGE:5312990 brain 5' read P
BI820420.1 Clone IMAGE:5175822 mixed 5' read P
BI820567.1 Clone IMAGE:5177207 mixed 5' read P
BI822766.1 Clone IMAGE:5181126 mixed 5' read P
BI822823.1 Clone IMAGE:5181127 mixed 5' read P
BI825105.1 Clone IMAGE:5180345 mixed 5' read P
BI918500.1 Clone IMAGE:5241085 brain 5' read P
BM193035.1 Clone TCBAP1296 lymph node
W45568.1 Clone IMAGE:323457 skin 3' read A
BM753507.1 Clone S10SNU1-15-E09 ascites 5' read P
BM835897.1 Clone S11SNU1-74-H01 ascites 5' read P
W72355.1 Clone IMAGE:345223 heart 3' read A
W74033.1 Clone IMAGE:345223 heart 5' read
BQ005197.1 Clone IMAGE:5848290 connective tissue 3' read A
BQ012204.1 Clone UI-1-BC1p-asj-h-09-0-UI placenta 3' read A
BQ012759.1 Clone UI-1-BC1p-auz-e-02-0-UI placenta 3' read A
BQ013210.1 Clone UI-1-BC1p-ayt-d-07-0-UI placenta 3' read PA
BQ428933.1 Clone IMAGE:6103769 testis 5' read P
BM145989.1 Clone TCAAP8480 bone marrow P
BM153455.1 Clone TCBAP1205 lymph node P
BQ889086.1 Clone IMAGE:6185560 ganglia 5' read P
AA219139.1 Clone IMAGE:650165 testis 3' read A
HY001150.1 Clone H04D004I03 testis
HY022600.1 Clone H04D076L18 testis
HY028518.1 Clone H04D098D20 testis P
HY029943.1 Clone H04D103N08 testis P
HY032116.1 Clone H04D111C07 testis P
HY040659.1 Clone H04D142H24 testis P
HY040861.1 Clone H04D143G16 testis P
HY184450.1 Clone H04D004I03 testis
HY205955.1 Clone H04D076L18 testis
HY212795.1 Clone H04D098D20 testis
HY214534.1 Clone H04D103N08 testis
HY216647.1 Clone H04D111C07 testis
HY226889.1 Clone H04D142H24 testis
HY231465.1 Clone H04D158C18 testis
AA280243.1 Clone IMAGE:712154 lymph node 5' read
AA281014.1 Clone IMAGE:711841 lymph node 3' read A
AA281540.1 Clone IMAGE:712154 lymph node 3' read A
AA302331.1 vascular 5' read
AA534446.1 Clone IMAGE:926214 intestine 3' read A
AA534576.1 Clone IMAGE:925935 intestine 3' read A
T24769.1 Clone 12H2 intestine
AA721229.1 Clone IMAGE:1300973 lymph node 3' read A
AA759331.1 Clone 1309341 testis 3' read A
AA809883.1 Clone IMAGE:1319745 lymph node 3' read A
AA831095.1 Clone IMAGE:1355290 lymph node 3' read A
AA831096.1 Clone IMAGE:1355294 lymph node 3' read A
AA831106.1 Clone IMAGE:1355293 lymph node 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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