> Breast cancer 2, early onset (BRCA2)
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UGID:136230     UniGene Hs.34012     Homo sapiens (human)   BRCA2 Links
Breast cancer 2, early onset (BRCA2)

Human protein-coding gene BRCA2. Represented by 71 ESTs from 45 cDNA libraries. Corresponds to reference sequence NM_000059.3. [UniGene 136230 - Hs.34012]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000050.2 BRCA2 gene product H. sapiens 100.0 3417
NP_001074470.1 Brca2 gene product M. musculus 62.9 3293
NP_001103864.2 brca2 gene product D. rerio 59.0 393
Other hits (2 of 22) [Show all]SpeciesId(%)Len(aa)
XP_509619.2 PREDICTED: breast cancer type 2 susceptibility protein P. troglodytes 99.2 3417
XP_003913789.1 PREDICTED: LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein P. anubis 94.3 3421

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: eye; liver; pancreas; mammary gland; testis; lymph node; bone marrow; embryonic tissue; thyroid; intestine; mouth; uncharacterized tissue; pharynx; mixed; brain; kidney; lung; vascular; placenta; bladder; connective tissue; ascites
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 13
Map position: 13q12.3
UniSTS entry: Chr 13 D13S1788
UniSTS entry: Chr 13 SHGC-81356
UniSTS entry: Chr 13 BRCA2
UniSTS entry: Chr 13 RH68440 [Map Viewer]
UniSTS entry: Chr 13 PMC23830P1
UniSTS entry: Chr 13 PMC310899P14
UniSTS entry: Chr 13 PMC13918P4
UniSTS entry: Chr 13 PMC13918P2
UniSTS entry: Chr 13 PMC13918P3
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (4)

BC047568.1 Homo sapiens breast cancer 2, early onset, mRNA (cDNA clone IMAGE:4838724) PA
NM_000059.3 Homo sapiens breast cancer 2, early onset (BRCA2), mRNA P
DQ897648.1 Homo sapiens breast and ovarian cancer susceptibility protein 2 truncated variant (BRCA2) mRNA, complete cds, alternatively spliced P
BC026160.1 Homo sapiens breast cancer 2, early onset, mRNA (cDNA clone IMAGE:4838723) PA

EST sequences (71)

BX102368.1 Clone IMAGp998N09367_;_IMAGE:193736 mixed P
AI343430.1 Clone IMAGE:2062194 intestine 3' read P
AI355687.1 Clone IMAGE:1952009 lung 3' read P
AI439788.1 Clone IMAGE:2134444 lymph node 3' read P
AI688632.1 Clone IMAGE:2330588 mixed 3' read P
AL044849.1 Clone DKFZp434D113 testis 5' read
AI949397.1 Clone IMAGE:2470940 kidney 3' read P
BX496533.1 Clone DKFZp779P2327 liver 5' read P
CD705611.1 pharynx P
CF143354.1 Clone IMAGE:3102360 lymph node 5' read P
AW362907.1 intestine P
AW368356.1 mouth P
CN266741.1 embryonic tissue 5' read
CN409236.1 embryonic tissue 5' read P
BE242124.1 Clone TCAAP1490 bone marrow
BE244582.1 Clone TCBAP0866 lymph node
BE245207.1 Clone TCBAP2852 lymph node
BE245239.1 Clone TCBAP2852 lymph node
BP220720.1 Clone COL04530 intestine 5' read P
BP269632.1 Clone JTH14261 thyroid 5' read P
BP280658.1 Clone KGR08574 brain 5' read P
BP289480.1 Clone LNF02269 lung 5' read P
BE503897.1 Clone IMAGE:3209960 uncharacterized tissue 3' read
BE552211.1 Clone IMAGE:3196350 uncharacterized tissue 3' read P
BP394255.1 Clone htp-58-94 pancreas 3' read P
H47777.1 Clone IMAGE:193736 mixed 5' read
H48122.1 Clone IMAGE:193736 mixed 3' read
BE869603.1 Clone IMAGE:3850805 intestine 5' read P
BY798783.2 Clone HE3842.seq eye 5' read P
AA767988.1 Clone IMAGE:1341016 lymph node 3' read A
DN912260.1 Clone MCF7_RNA_L_13_O13 mammary gland P
DN912261.1 Clone MCF7_RNA_L_13_O13 mammary gland P
DN915584.1 Clone MCF7_RNA_L_20_G01 mammary gland P
DN915585.1 Clone MCF7_RNA_L_20_G01 mammary gland P
DA542875.1 Clone HCASM2000166 vascular 5' read P
AU143426.1 Clone Y79AA1001908 eye 5' read P
DA807080.1 Clone OCBBF3022614 brain 5' read P
DB329032.1 Clone PLACE7013301 placenta 3' read P
DB074188.1 Clone TESTI4017736 testis 5' read P
DB069915.1 Clone TESTI4012288 testis 5' read P
DB384673.1 Clone Y79AA1001908 eye 3' read P
DB071759.1 Clone TESTI4014658 testis 5' read P
BF805550.1 intestine P
BF814836.1 intestine
BG166383.1 Clone IMAGE:4447374 kidney 5' read P
BG166449.1 Clone IMAGE:4447444 kidney 5' read P
BG290037.1 Clone IMAGE:4513800 bladder 5' read P
BG502609.1 Clone IMAGE:4657280 testis 5' read P
BG562419.1 Clone IMAGE:4709026 liver 5' read
BG614511.1 Clone IMAGE:4773567 testis 5' read P
BG459792.1 connective tissue P
BG772619.1 Clone IMAGE:4837759 testis 5' read P
BG773127.1 Clone IMAGE:4838724 testis 5' read P
BG773203.1 Clone IMAGE:4838723 testis 5' read P
AL601892.1 Clone DKFZp313O137 uncharacterized tissue 5' read P
AL602008.1 Clone DKFZp313K018 uncharacterized tissue 5' read P
BM171992.1 Clone IMAGE:4773567 testis 5' read P
BM839248.1 Clone S9SNU601-83-C04 ascites 5' read P
BQ226936.1 Clone IMAGE:6015232 uncharacterized tissue 5' read P
BQ439258.1 Clone IMAGE:6016305 uncharacterized tissue 5' read P
BM150414.1 Clone TCBAP0866 lymph node PA
BU568005.1 Clone IMAGE:6614780 testis 5' read
AA215820.1 Clone IMAGE:683739 lymph node 5' read P
BU954242.1 Clone IMAGE:6725734 mixed 5' read P
AA280905.1 Clone IMAGE:711698 lymph node 5' read P
AA333018.1 embryonic tissue 5' read P
AA740751.1 Clone IMAGE:1286665 lymph node 3' read P
AA741449.1 Clone IMAGE:1286225 lymph node 3' read
AA742610.1 Clone IMAGE:1285499 lymph node 3' read
AA765738.1 Clone IMAGE:1304082 lymph node 3' read P
AA938167.1 Clone IMAGE:1340447 lymph node 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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