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UGID:173402     UniGene Hs.272225     Homo sapiens (human)   TRPM6
Transient receptor potential cation channel, subfamily M, member 6 (TRPM6)

Human protein-coding gene TRPM6. Represented by 85 ESTs from 22 cDNA libraries. EST representation biased toward chondrosarcoma. Corresponds to 3 reference sequences (different isoforms). [UniGene 173402 - Hs.272225]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_060132.3 TRPM6 gene product H. sapiens 100.0 2021
XP_003312158.1 PREDICTED: transient receptor potential cation channel subfamily M member 6 isoform 1 P. troglodytes 99.8 2021
NP_700466.1 Trpm6 gene product M. musculus 83.4 2027
NP_001025232.1 trpm7 gene product D. rerio 64.8 1742
NP_001177950.1 transient receptor potential cation channel, subfamily M, member 7 X. laevis 64.1 1863
NP_001036550.1 trpm, isoform C D. melanogaster 47.4 1014
NP_001129788.1 Protein GON-2, isoform e C. elegans 46.9 728
Other hits (2 of 32) [Show all]SpeciesId(%)Len(aa)
XP_002800188.1 PREDICTED: transient receptor potential cation channel subfamily M member 6 isoform 2 M. mulatta 97.5 2024
XP_003911864.1 PREDICTED: transient receptor potential cation channel subfamily M member 6 isoform 1 P. anubis 97.3 2024

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: chondrosarcoma [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uncharacterized tissue; kidney; intestine; brain; testis; mixed; liver; lung; trachea; bone; eye
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 9
Map position: 9q21.13
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

AY333288.1 Homo sapiens M6-kinase 3 (TRPM6) mRNA, complete cds, alternatively spliced P
AY333287.1 Homo sapiens M6-kinase 2 (TRPM6) mRNA, complete cds, alternatively spliced P
AY333286.1 Homo sapiens M6-kinase 1 (TRPM6) mRNA, complete cds, alternatively spliced P
AY333284.1 Homo sapiens transient receptor potential cation channel subfamily M member 6 variant c (TRPM6) mRNA, complete cds, alternatively spliced P
AY333283.1 Homo sapiens transient receptor potential cation channel subfamily M member 6 variant b (TRPM6) mRNA, complete cds, alternatively spliced P
AY333282.1 Homo sapiens transient receptor potential cation channel subfamily M member 6 variant a (TRPM6) mRNA, complete cds, alternatively spliced P
AK000094.1 Homo sapiens cDNA FLJ20087 fis, clone COL03793 PA
NM_017662.4 Homo sapiens transient receptor potential cation channel, subfamily M, member 6 (TRPM6), transcript variant a, mRNA P
AK026281.1 Homo sapiens cDNA: FLJ22628 fis, clone HSI06177 PA
AK225207.1 Homo sapiens mRNA for transient receptor potential cation channel, subfamily M, member 6 variant, clone: COL03793 PA
AF350881.2 Homo sapiens channel kinase 2 (CHAK2) mRNA, complete cds P
AK057748.1 Homo sapiens cDNA FLJ25019 fis, clone CBL01642 P
AF448232.1 Homo sapiens LTRPC6 channel kinase 2 (TRPM6) mRNA, complete cds P
NM_001177311.1 Homo sapiens transient receptor potential cation channel, subfamily M, member 6 (TRPM6), transcript variant c, mRNA P
NM_001177310.1 Homo sapiens transient receptor potential cation channel, subfamily M, member 6 (TRPM6), transcript variant b, mRNA P

EST sequences (85)

CB159778.1 Clone L18POOL1n1-26-H04 liver 5' read
AI272662.1 Clone IMAGE:1876610 mixed 3' read
BX281186.1 Clone IMAGp998G056127_;_IMAGE:2463388 kidney
AI935605.1 Clone IMAGE:2463388 kidney 3' read
BX412547.1 Clone CS0DF002YD08 brain 3' read P
BX440183.2 Clone CS0DF002YD08 brain 5' read P
CD244036.1 Clone IMAGE:30377599 testis 5' read P
CD628399.1 uncharacterized tissue P
CD628400.1 uncharacterized tissue P
CD628401.1 uncharacterized tissue P
CD628402.1 uncharacterized tissue
CD628403.1 uncharacterized tissue
CD628404.1 uncharacterized tissue P
CD628405.1 uncharacterized tissue P
CD628406.1 uncharacterized tissue P
CD628407.1 uncharacterized tissue
CD628415.1 uncharacterized tissue
CD628416.1 uncharacterized tissue P
CD628417.1 uncharacterized tissue P
CD628418.1 uncharacterized tissue P
CD628419.1 uncharacterized tissue
CD628420.1 uncharacterized tissue P
CD628421.1 uncharacterized tissue P
CD628422.1 uncharacterized tissue P
CD628423.1 uncharacterized tissue P
CD628431.1 uncharacterized tissue P
CD628432.1 uncharacterized tissue P
CD628433.1 uncharacterized tissue
CD628434.1 uncharacterized tissue P
CD628435.1 uncharacterized tissue P
CD628436.1 uncharacterized tissue P
CD628437.1 uncharacterized tissue P
CD628438.1 uncharacterized tissue P
CD628439.1 uncharacterized tissue P
CD628447.1 uncharacterized tissue
CD628448.1 uncharacterized tissue P
CD628395.1 uncharacterized tissue P
CD628396.1 uncharacterized tissue
CD628397.1 uncharacterized tissue P
CD628398.1 uncharacterized tissue
CD628408.1 uncharacterized tissue P
CD628409.1 uncharacterized tissue P
CD628410.1 uncharacterized tissue P
CD628411.1 uncharacterized tissue P
CD628412.1 uncharacterized tissue P
CD628413.1 uncharacterized tissue P
CD628414.1 uncharacterized tissue P
CD628424.1 uncharacterized tissue P
CD628425.1 uncharacterized tissue
CD628426.1 uncharacterized tissue P
CD628427.1 uncharacterized tissue
CD628428.1 uncharacterized tissue P
CD628429.1 uncharacterized tissue P
CD628430.1 uncharacterized tissue P
CD628440.1 uncharacterized tissue P
CD628441.1 uncharacterized tissue P
CD628442.1 uncharacterized tissue P
CD628443.1 uncharacterized tissue P
CD628444.1 uncharacterized tissue P
CD628445.1 uncharacterized tissue P
CD628446.1 uncharacterized tissue P
AW772222.1 Clone IMAGE:3033195 kidney 3' read
BP208668.1 Clone CBL01638 brain 5' read P
BP208672.1 Clone CBL01642 brain 5' read P
BP220589.1 Clone COL03793 intestine 5' read P
BP261360.1 Clone HSI03280 intestine 5' read P
BP264326.1 Clone HSI15507 intestine 5' read P
BP270293.1 Clone KAR01807 intestine 5' read P
BE465471.1 Clone IMAGE:3183499 kidney 3' read P
DR006418.1 Clone TC124051 intestine 5' read P
BP418612.1 Clone HIE01775r intestine 3' read
BF115110.1 Clone IMAGE:3134236 kidney 3' read
BF115147.1 Clone IMAGE:3135148 kidney 3' read
BF447669.1 Clone IMAGE:3706220 lung 3' read
DA272077.1 Clone BRCAN2026811 brain 5' read P
DB235133.1 Clone TRACH3029978 trachea 5' read P
DB063269.1 Clone TESTI4003684 testis 5' read P
BG428448.1 Clone IMAGE:4608901 kidney 5' read
BI754451.1 Clone IMAGE:5193112 brain 5' read P
BQ276583.1 Clone IMAGE:5809512 mixed 5' read
GD256398.1 Clone da0_002302 5' read
HY054706.1 Clone H04D193M18 testis
HY242704.1 Clone H04D193M18 testis
CA420033.1 Clone UI-H-FH0-bcg-n-16-0-UI bone 3' read A
AA780689.1 Clone IMAGE:868096 eye 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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