> Acetyl-CoA acetyltransferase 1 (ACAT1)
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UGID:166937     UniGene Hs.232375     Homo sapiens (human)   ACAT1 Links
Acetyl-CoA acetyltransferase 1 (ACAT1)

Human protein-coding gene ACAT1. Represented by 152 ESTs from 109 cDNA libraries. Corresponds to reference sequence NM_000019.3. [UniGene 166937 - Hs.232375]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_508738.2 PREDICTED: acetyl-CoA acetyltransferase, mitochondrial P. troglodytes 100.0 426
NP_000010.1 ACAT1 gene product H. sapiens 100.0 426
XP_001103928.1 PREDICTED: acetyl-CoA acetyltransferase, mitochondrial M. mulatta 99.5 426
XP_003910695.1 PREDICTED: acetyl-CoA acetyltransferase, mitochondrial P. anubis 99.5 426
NP_659033.1 Acat1 gene product M. musculus 89.9 423
NP_001003746.1 acat1 gene product D. rerio 83.0 411
NP_001086028.1 acetyl-CoA acetyltransferase B, mitochondrial precursor X. laevis 80.9 417
NP_572414.1 CG10932 D. melanogaster 69.5 406
NP_495455.2 Protein KAT-1 C. elegans 57.2 385
NP_851154.1 acetyl-CoA acetyltransferase, cytosolic 1 A. thaliana 56.1 391
XP_964434.2 acetyl-CoA acetyltransferase N. crassa 53.4 399
XP_001694888.1 predicted protein C. reinhardtii 51.9 393
NP_015297.1 acetyl-CoA C-acetyltransferase S. cerevisiae 48.5 395
Other hits (2 of 60) [Show all]SpeciesId(%)Len(aa)
XP_004016590.1 PREDICTED: acetyl-CoA acetyltransferase, mitochondrial, partial O. aries 95.9 412
NP_001039540.1 ACAT1 gene product B. taurus 94.8 421

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; stomach; muscle; intestine; uncharacterized tissue; embryonic tissue; heart; mammary gland; uterus; mixed; placenta; lung; bladder; mouth; ovary; blood; esophagus; eye; adrenal gland; testis; kidney; liver; prostate; adipose tissue; connective tissue; skin; ascites; larynx; ganglia; pancreas; umbilical cord; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q22.3
UniSTS entry: Chr 11 D11S4336 [Map Viewer]
UniSTS entry: Chr 11 D11S2051
UniSTS entry: Chr 11 D11S2241E
UniSTS entry: GDB:555481
UniSTS entry: Chr 11 STS-AA010069 [Map Viewer]
UniSTS entry: GDB:555487
UniSTS entry: GDB:555490
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

S70578.1 acetoacetyl-coenzyme A thiolase {Q272STOP, exon 8} [human, GK07, Pre-mRNA Partial Mutant, 100 nt]
NM_000019.3 Homo sapiens acetyl-CoA acetyltransferase 1 (ACAT1), nuclear gene encoding mitochondrial protein, mRNA PA
BC010942.1 Homo sapiens acetyl-Coenzyme A acetyltransferase 1, mRNA (cDNA clone IMAGE:4278329), complete cds PA
AK312574.1 Homo sapiens cDNA, FLJ92949, Homo sapiens acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) (ACAT1), nuclear gene encoding mitochondrial protein, mRNA P
D90228.1 Homo sapiens mRNA for mitochondrial acetoacetyl-CoA thiolase precursor, complete cds P
AF086561.1 Homo sapiens full length insert cDNA clone ZE16B08

EST sequences (152)

AI139512.1 Clone IMAGE:1710629 uterus 3' read P
AI202672.1 Clone IMAGE:1944363 prostate 3' read
AI471445.1 Clone IMAGE:2156283 intestine 3' read P
AI567965.1 Clone IMAGE:2215704 ovary 3' read
AI654154.1 Clone IMAGE:2283665 kidney 3' read A
F26363.1 Clone s4000053C06 muscle A
F27643.1 Clone s4000011A03 muscle P
F28457.1 Clone s3000016E12 muscle P
F28477.1 Clone s3000016H12 muscle
F36678.1 Clone sH5-000018-0/H11 muscle
AI683154.1 Clone IMAGE:2263014 uterus 3' read P
F00504.1 Clone 06D09 muscle
AL041431.1 Clone DKFZp434D1817 testis 3' read PA
AI871665.1 Clone IMAGE:2292807 ovary 3' read A
BX361786.2 Clone CS0DJ004YL09 blood 3' read P
BX509752.1 Clone DKFZp686F0281 muscle 5' read P
AW081574.1 Clone IMAGE:2585113 intestine 3' read PA
CF595927.1 Clone IMAGE:30703564 stomach 5' read P
AW297552.1 Clone IMAGE:2731220 uncharacterized tissue 3' read PA
AW750026.1 mammary gland
AW804103.1 uterus
AW945161.1 uncharacterized tissue
AW950643.1 uncharacterized tissue
CN369577.1 embryonic tissue 5' read P
AW997146.1 mammary gland P
CV030068.1 mixed 5' read P
BP194596.1 Clone ADB05576 brain 5' read P
BP227188.1 Clone DMC04872 uncharacterized tissue 5' read P
BP318763.2 Clone PCD08452 heart 5' read A
BP360666.1 Clone THR02642 brain 5' read P
BP373136.1 Clone UBA05430 umbilical cord 5' read P
BP257974.1 Clone HRT02321 heart 5' read P
BP258806.1 Clone HRT04621 heart 5' read P
BP308813.1 Clone NRB06478 brain 5' read P
BP375630.1 Clone WMC01194 uterus 5' read P
BP377795.1 Clone WMC09121 uterus 5' read P
BP380880.1 Clone Zrv62488 brain 5' read P
BP380941.1 Clone Zrv6c455 brain 5' read P
BP382319.1 Clone adSH00628 adipose tissue 5' read P
CV322052.1 bladder P
CV329377.1 kidney P
CV424322.1 intestine P
AU310532.1 Clone Nbla-23361 uncharacterized tissue 5' read P
DN990305.1 Clone TC105810 brain 5' read P
DR004764.1 Clone TC125282 placenta 5' read P
BE927504.1 intestine
AV708226.1 Clone ADCAOA09 adrenal gland 5' read P
T28635.1 liver 5' read
AU117943.1 Clone HEMBA1002550 embryonic tissue 5' read P
DR760374.1 Clone IMAGE:7969689 embryonic tissue 5' read A
BF667268.1 Clone IMAGE:4278329 brain 5' read
DA091679.1 Clone BRACE2047717 brain 5' read P
DA008540.1 Clone ADIPS2000270 adipose tissue 5' read P
DA128909.1 Clone BRACE3052628 brain 5' read P
DA129378.1 Clone BRALZ2000241 brain 5' read P
DA430298.1 Clone COLON2006542 intestine 5' read P
DA352036.1 Clone BRSSN2015183 brain 5' read P
DA615995.1 Clone IMR322015350 brain 5' read P
DA688222.1 Clone NT2NE2006962 5' read P
DA583502.1 Clone HLUNG2003120 lung 5' read P
DA357405.1 Clone BRSTN2002760 brain 5' read P
DA632177.1 Clone KIDNE2013712 kidney 5' read P
DA560534.1 Clone HEART2001346 heart 5' read P
AW605808.1 mouth
AW605830.1 mouth
DA668873.1 Clone NESOP2001745 esophagus 5' read P
AU142655.2 Clone Y79AA1000667 eye 5' read P
AU143159.1 Clone Y79AA1001483 eye 5' read P
DA493635.1 Clone FCBBF3005674 brain 5' read P
AU144630.1 Clone HEMBA1002550 embryonic tissue 3' read PA
DA566797.1 Clone HEART2009874 heart 5' read P
DA914792.1 Clone SKNSH2009454 brain 5' read P
DB010738.1 Clone TCOLN2001859 intestine 5' read P
AU159921.1 Clone Y79AA1000667 eye 3' read A
AU160294.1 Clone Y79AA1001483 eye 3' read PA
BF431005.1 Clone IMAGE:3259581 kidney 3' read
DB039726.1 Clone TESTI2026328 testis 5' read P
DA893552.1 Clone SKMUS2000683 muscle 5' read P
DA893998.1 Clone SKMUS2001210 muscle 5' read P
DA900126.1 Clone SKMUS2008846 muscle 5' read P
BF528753.1 Clone IMAGE:4179153 brain 5' read P
DB027008.1 Clone TESTI2009372 testis 5' read P
DB075461.1 Clone TESTI4019352 testis 5' read P
DB310316.1 Clone BRSSN2011065 brain 3' read
DB057536.1 Clone TESTI2049751 testis 5' read P
DW410894.1 liver
BF814713.1 intestine
BG030485.1 Clone IMAGE:4392196 mammary gland 5' read A
BF968297.1 Clone IMAGE:4357562 adrenal gland 5' read P
BG165125.1 Clone IMAGE:4453909 kidney 5' read P
DB559066.1 Clone H033027P14 brain 3' read
DB489516.1 Clone H033027P14 brain 5' read P
EB388792.1 Clone nbj50d03 brain 5' read P
EC457467.1 prostate
EC470702.1 prostate
EC551976.1 prostate
AU100279.1 Clone Zrv6c455 uncharacterized tissue 5' read
BG577242.1 Clone IMAGE:4708492 mammary gland 5' read P
BG611640.1 Clone IMAGE:4739081 prostate 5' read
BG196361.1 connective tissue P
BG210420.1 connective tissue A
BG740338.1 Clone IMAGE:4780652 skin 5' read P
BG929263.1 connective tissue
BG874804.1 mammary gland P
BG874806.1 mammary gland P
BG874811.1 mammary gland P
BI012701.1 lung
BI014888.1 lung
BI520566.1 Clone IMAGE:5163548 brain 5' read A
BI520628.1 Clone IMAGE:5163548 brain 3' read
BI763850.1 Clone IMAGE:5189977 mixed 5' read PA
BI870235.1 Clone IMAGE:5403753 liver 5' read P
BM457169.1 Clone IMAGE:5583430 uncharacterized tissue 5' read P
BM472327.1 Clone IMAGE:5576486 uncharacterized tissue 5' read P
BM474090.1 Clone IMAGE:5521497 uterus 5' read P
BM789408.1 Clone S22SNU16-5-E09 ascites 5' read A
BQ276954.1 Clone IMAGE:5810038 mixed 5' read P
AA010069.1 Clone IMAGE:359127 heart 3' read
BQ302657.1 mammary gland P
BQ304506.1 mammary gland P
BQ317101.1 intestine P
BQ317515.1 intestine P
BQ317918.1 intestine P
BQ319846.1 intestine
BQ339117.1 brain P
BQ344399.1 brain P
BQ344414.1 brain P
BQ348355.1 mouth
BQ348673.1 mouth P
BQ353622.1 larynx
BQ353629.1 larynx
BQ375090.1 testis P
BQ378718.1 uterus P
BU165358.1 Clone IMAGE:6144756 eye 5' read
BU146622.1 Clone IMAGE:6182007 ganglia 5' read P
C01800.1 uncharacterized tissue
FN168284.1 Clone 283995_0721_0431
FN153606.1 Clone 250619_2339_4011
FN151572.1 Clone 246093_1041_3479
FN052860.1 Clone 010014_1969_3099
FN081177.1 Clone 066383_1798_1783
FN119577.1 Clone 170049_1517_0727
FN063095.1 Clone 023189_2720_0853
BU861263.1 Clone IMAGE:6652746 mixed 5' read A
HY029831.1 Clone H04D103G20 testis P
AA312208.1 kidney 3' read
AA312281.1 kidney 5' read
CA776496.1 Clone IMAGE:6216435 pancreas 3' read P
CA776724.1 Clone IMAGE:6216435 pancreas 5' read P
T85734.1 Clone IMAGE:112345 mixed 5' read
AA528456.1 Clone IMAGE:910979 bone A
AA550785.1 Clone IMAGE:999420 prostate


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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