> Histidine ammonia-lyase (HAL)
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UGID:160505     UniGene Hs.190783     Homo sapiens (human)   HAL Order cDNA clone, Links
Histidine ammonia-lyase (HAL)

Human protein-coding gene HAL. Represented by 65 ESTs from 23 cDNA libraries. EST representation biased toward fetus. Corresponds to 3 reference sequences (different isoforms). [UniGene 160505 - Hs.190783]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_002099.1 HAL gene product H. sapiens 100.0 656
XP_509282.3 PREDICTED: histidine ammonia-lyase isoform 2 P. troglodytes 99.5 656
NP_034531.1 histidine ammonia-lyase M. musculus 95.6 656
NP_001086064.1 MGC81887 protein X. laevis 92.2 642
NP_001082926.1 hal gene product D. rerio 87.4 641
NP_509820.1 Protein HALY-1 C. elegans 64.5 636
Other hits (2 of 31) [Show all]SpeciesId(%)Len(aa)
XP_001107685.1 PREDICTED: histidine ammonia-lyase isoform 1 M. mulatta 98.5 656
XP_003907030.1 PREDICTED: histidine ammonia-lyase isoform 1 P. anubis 98.5 656

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: fetus [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: liver; mixed; blood; heart; muscle; pancreas; eye; skin; uncharacterized tissue; testis
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q22-q24.1
UniSTS entry: Chr 12 D12S1891 [Map Viewer]
UniSTS entry: Chr 12 GDB:384907
UniSTS entry: Chr 12 RH67993 [Map Viewer]
UniSTS entry: Chr 12 SHGC-84577
UniSTS entry: Chr 12 RH44629 [Map Viewer]
UniSTS entry: Chr 12 STS-R01181 [Map Viewer]
UniSTS entry: Chr 12 SGC33859 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

NM_002108.3 Homo sapiens histidine ammonia-lyase (HAL), transcript variant 1, mRNA PA
BC096098.3 Homo sapiens histidine ammonia-lyase, mRNA (cDNA clone MGC:116740 IMAGE:40001286), complete cds P
BC096097.3 Homo sapiens histidine ammonia-lyase, mRNA (cDNA clone MGC:116739 IMAGE:40001285), complete cds P
BC096096.1 Homo sapiens histidine ammonia-lyase, mRNA (cDNA clone IMAGE:40001284), complete cds P
BC096099.1 Homo sapiens histidine ammonia-lyase, mRNA (cDNA clone MGC:116741 IMAGE:40001287), complete cds P
AK298736.1 Homo sapiens cDNA FLJ59235 complete cds, highly similar to Histidine ammonia-lyase (EC 4.3.1.3) P
AK297004.1 Homo sapiens cDNA FLJ57123 complete cds, highly similar to Histidine ammonia-lyase (EC 4.3.1.3) P
AK303544.1 Homo sapiens cDNA FLJ61019 complete cds, highly similar to Histidine ammonia-lyase (EC 4.3.1.3) P
D16626.1 Homo sapiens mRNA for histidase, complete cds P
NM_001258334.1 Homo sapiens histidine ammonia-lyase (HAL), transcript variant 3, mRNA PA
NM_001258333.1 Homo sapiens histidine ammonia-lyase (HAL), transcript variant 2, mRNA PA

EST sequences (65)

AI033058.1 Clone IMAGE:1654396 mixed 3' read A
AI140162.1 Clone IMAGE:1693781 heart 3' read
BX089267.1 Clone IMAGp998K19123_;_IMAGE:125322 mixed
CB153364.1 Clone L17N670205-2-B02 liver 5' read
CB156949.1 Clone L17N670205n1-6-B12 liver 5' read
CB161424.1 Clone L17N670205n1-44-E06 liver 5' read
CB162549.1 Clone L17N670205n1-27-C04 liver 5' read
AI248003.1 Clone IMAGE:1849362 mixed 3' read A
AI249025.1 Clone IMAGE:1851039 mixed 3' read
BX367043.2 Clone CS0DJ009YJ02 blood 3' read P
BX422319.2 Clone CS0DM003YN21 liver 5' read P
CV337655.1 blood P
AV646003.2 Clone GLCAHG02 liver 3' read
AV652386.1 Clone GLCCZG11 liver 3' read
AV652699.1 Clone GLCDDB06 liver 3' read
AV652722.1 Clone GLCDDD05 liver 3' read
AV652736.1 Clone GLCDDE07 liver 3' read
AV652737.1 Clone GLCDDE08 liver 3' read
AV655174.1 Clone GLCEDE08 liver 3' read A
AV655741.1 Clone GLCEKA06 liver 3' read
AV656058.1 Clone GLCEND04 liver 3' read
AV656894.2 Clone GLCEWB01 liver 3' read
BP383988.1 Clone hbt00204 pancreas 3' read A
BP398224.1 Clone htp-21-86 pancreas 3' read A
AV683598.1 Clone GKCDMC03 liver 5' read P
AV688965.1 Clone GKCCED11 liver 5' read P
AV693031.2 Clone GKCEMB03 liver 5' read P
BE970992.1 Clone IMAGE:3934558 muscle 5' read
BE971299.1 Clone IMAGE:3934997 muscle 5' read
R96925.1 Clone IMAGE:200365 mixed 3' read
H54544.1 Clone IMAGE:203190 mixed 5' read
DB188302.1 Clone TLIVE2008620 liver 5' read
DB188320.1 Clone TLIVE2008643 liver 5' read P
DB181479.1 Clone TLIVE2000287 liver 5' read P
BF901901.1 blood
BF902727.1 blood
BF902949.1 blood
BG567115.1 Clone IMAGE:4723359 liver 5' read
BG617660.1 Clone IMAGE:4734544 liver 5' read
N54942.1 Clone IMAGE:244983 mixed 3' read A
N55360.1 Clone IMAGE:245881 mixed 3' read A
BI029062.1 blood P
BI030195.1 blood P
N76272.1 Clone IMAGE:244983 mixed 5' read
BJ993129.1 Clone hmfn-0675 liver 5' read P
CU445318.1 skin P
BM713716.1 Clone UI-E-EJ0-ahq-p-13-0-UI eye 5' read
W70115.1 Clone IMAGE:344292 heart 3' read A
W69965.1 Clone IMAGE:344292 heart 5' read
W72690.1 Clone IMAGE:345832 heart 3' read
W77805.1 Clone IMAGE:345832 heart 5' read P
W86775.1 Clone IMAGE:416803 mixed 5' read
W86776.1 Clone IMAGE:416803 mixed 3' read
C01635.1 uncharacterized tissue
AA232983.1 Clone IMAGE:666670 mixed 5' read
AA233369.1 Clone IMAGE:666670 mixed 3' read A
BU739014.1 Clone UI-E-EJ0-ahq-p-13-0-UI eye 3' read A
HY184866.1 Clone H04D005L13 testis
T87436.1 Clone IMAGE:115442 mixed 5' read
R01181.1 Clone IMAGE:123746 mixed 3' read
R01292.1 Clone IMAGE:123746 mixed 5' read P
AA702357.1 Clone IMAGE:447785 mixed 3' read A
R05983.1 Clone IMAGE:125322 mixed 5' read
R05984.1 Clone IMAGE:125322 mixed 3' read
AA778922.1 Clone IMAGE:452573 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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