> Pappalysin 2 (PAPPA2)
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UGID:159865     UniGene Hs.187284     Homo sapiens (human)   PAPPA2 Links
Pappalysin 2 (PAPPA2)

Human protein-coding gene PAPPA2. Represented by 319 ESTs from 103 cDNA libraries. EST representation biased toward adult. Corresponds to 2 reference sequences (different isoforms). [UniGene 159865 - Hs.187284]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_064714.2 PAPPA2 gene product H. sapiens 100.0 1790
XP_514020.2 PREDICTED: pappalysin-2 P. troglodytes 99.5 1790
NP_001078845.1 pappalysin 2 precursor M. musculus 84.5 1788
XP_695417.3 PREDICTED: pappalysin-2-like D. rerio 56.3 1750
Other hits (2 of 19) [Show all]SpeciesId(%)Len(aa)
XP_002808308.1 PREDICTED: LOW QUALITY PROTEIN: pappalysin-2-like M. mulatta 96.5 1793
XP_001498272.1 PREDICTED: pappalysin-2 isoform 1 E. caballus 88.0 1789

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; mixed; uterus; eye; kidney; brain; pancreas; intestine; lung; uncharacterized tissue; pituitary gland; prostate; epididymis; stomach; skin; heart; muscle; bone; liver; testis
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q23-q25
UniSTS entry: Chr 1 A005P32
UniSTS entry: Chr 1 G20401
UniSTS entry: Chr 1 G20532
UniSTS entry: Chr 1 A005V17
UniSTS entry: Chr 1 WI-11981 [Map Viewer]
UniSTS entry: Chr 1 RH12244 [Map Viewer]
UniSTS entry: Chr 1 RH12616
UniSTS entry: Chr 1 PLAC3_8080
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

BX649062.1 Homo sapiens mRNA; cDNA DKFZp779M1134 (from clone DKFZp779M1134) A
BC062665.1 Homo sapiens pappalysin 2, mRNA (cDNA clone IMAGE:4714116) A
AB209369.1 Homo sapiens mRNA for Pappalysin-2 precursorvariant protein P
AJ278348.1 Homo sapiens mRNA for pregnancy-associated plasma protein-E (PAPPE gene) P
BC104644.1 Homo sapiens pappalysin 2, mRNA (cDNA clone IMAGE:4604942) A
BC117193.1 Homo sapiens pappalysin 2, mRNA (cDNA clone IMAGE:40125744), complete cds P
BC117195.1 Homo sapiens pappalysin 2, mRNA (cDNA clone IMAGE:40125746), complete cds P
AF311940.1 Homo sapiens pregnancy-associated plasma preproprotein-A2 mRNA, complete cds P
AF342990.1 Homo sapiens pregnancy-associated plasma protein E2 (PAPPE) mRNA, complete cds, alternatively spliced PA
AF342989.1 Homo sapiens pregnancy-associated plasma protein E1 (PAPPE) mRNA, complete cds, alternatively spliced PA
BC152552.1 Homo sapiens cDNA clone IMAGE:40147673 P
AK096718.1 Homo sapiens cDNA FLJ39399 fis, clone PLACE6011041
NM_021936.2 Homo sapiens pappalysin 2 (PAPPA2), transcript variant 2, mRNA P
NM_020318.2 Homo sapiens pappalysin 2 (PAPPA2), transcript variant 1, mRNA PA

EST sequences (319)

AI052258.1 Clone IMAGE:1675977 mixed 3' read A
R21178.1 Clone IMAGE:130277 placenta 5' read
R21408.1 Clone IMAGE:130078 placenta 3' read
AI088411.1 Clone IMAGE:1696500 uterus 3' read A
AI095734.1 Clone IMAGE:1697254 uterus 3' read A
AI096347.1 Clone IMAGE:1697897 uterus 3' read A
R22796.1 Clone IMAGE:130277 placenta 3' read A
AI127580.1 Clone IMAGE:1710704 uterus 3' read A
AI129688.1 Clone IMAGE:1711627 uterus 3' read A
R23467.1 Clone IMAGE:132097 placenta 5' read
AI146678.1 Clone IMAGE:1697942 uterus 3' read A
R24261.1 Clone IMAGE:131245 placenta 3' read
R24367.1 Clone IMAGE:131245 placenta 5' read
AI151429.1 Clone IMAGE:1721319 uterus 3' read A
BX099965.1 Clone IMAGp998M15210_;_IMAGE:142262 placenta
AI167624.1 Clone IMAGE:1509006 mixed 3' read
AI189116.1 Clone IMAGE:1722279 uterus 3' read A
AI189129.1 Clone IMAGE:1722308 uterus 3' read
AI189289.1 Clone IMAGE:1722826 placenta 3' read
AI221072.1 Clone IMAGE:1759042 placenta 3' read
R28290.1 Clone IMAGE:134736 placenta 3' read A
R28351.1 Clone IMAGE:133626 placenta 3' read
R28555.1 Clone IMAGE:133626 placenta 5' read
R30918.1 Clone IMAGE:134072 placenta 5' read
AI247861.1 Clone IMAGE:1848861 mixed 3' read A
AI273506.1 Clone IMAGE:1876672 mixed 3' read A
AI274143.1 Clone IMAGE:1876452 mixed 3' read
AI435078.1 Clone IMAGE:2126396 mixed 3' read
AI436332.1 Clone IMAGE:2126255 mixed 3' read A
AI373926.1 Clone IMAGE:2041910 uterus 3' read A
AI469828.1 Clone IMAGE:2148520 mixed 3' read
AI469936.1 Clone IMAGE:2148627 mixed 3' read A
AI492466.1 Clone IMAGE:2131792 kidney 3' read A
AI580272.1 Clone IMAGE:2161085 kidney 3' read A
AI580767.1 Clone IMAGE:2043110 uterus 3' read A
AI631762.1 Clone IMAGE:2300124 kidney 3' read
AI742900.1 Clone IMAGE:2368257 mixed 3' read A
AI768227.1 Clone IMAGE:2371629 mixed 3' read
BX280813.1 Clone IMAGp998C202227_;_IMAGE:897355 kidney
AI864245.1 Clone IMAGE:2369828 mixed 3' read A
CB992643.1 Clone IMAGE:30339124 placenta 5' read P
CB992910.1 Clone IMAGE:30330912 placenta 5' read P
CB993111.1 Clone IMAGE:30335200 placenta 5' read P
CB995260.1 Clone IMAGE:30339954 placenta 5' read P
CB961346.1 Clone IMAGE:30337790 placenta 5' read
BX399177.2 Clone CS0DI070YP19 placenta 5' read
BX324772.2 Clone CS0DI040YL15 placenta 3' read
BX337486.2 Clone CS0DI042YO08 placenta 3' read
BX324773.2 Clone CS0DI040YL15 placenta 5' read
BX337487.2 Clone CS0DI042YO08 placenta 5' read
BX329125.2 Clone CS0DI084YF21 placenta 3' read P
BX348427.2 Clone CS0DI084YF21 placenta 5' read P
BX379932.2 Clone CS0DI041YF07 placenta 3' read
BX380768.1 Clone CS0DI057YK22 placenta 3' read
BX379933.2 Clone CS0DI041YF07 placenta 5' read P
BX380769.2 Clone CS0DI057YK22 placenta 5' read
BX399176.2 Clone CS0DI070YP19 placenta 3' read
BX397668.2 Clone CS0DI041YE03 placenta 3' read
BX397669.2 Clone CS0DI041YE03 placenta 5' read
BX439558.2 Clone CS0DE011YP20 placenta 5' read
BX451429.2 Clone CS0DE011YP20 placenta 5' read
BX491718.1 Clone DKFZp781F2312 uncharacterized tissue 5' read
BX498343.1 Clone DKFZp779C1739 liver 5' read
AW028523.1 Clone IMAGE:2530796 kidney 3' read A
AW080708.1 Clone IMAGE:2585489 intestine 3' read A
CF527876.1 Clone UI-1-BC0-adz-f-10-0-UI placenta 3' read A
CF528120.1 Clone UI-1-BC0-aeb-h-10-0-UI placenta 3' read A
CF528139.1 Clone UI-1-BC0-aeh-c-07-0-UI placenta 3' read A
AW235574.1 Clone IMAGE:2694209 kidney 3' read A
R62533.1 Clone IMAGE:139170 placenta 5' read
R62534.1 Clone IMAGE:139170 placenta 3' read A
R63531.1 Clone IMAGE:138749 placenta 3' read A
R63580.1 Clone IMAGE:138749 placenta 5' read
R65875.1 Clone IMAGE:140065 placenta 5' read
CK299736.1 Clone UI-E-EJ1-ajw-d-16-0-UI eye 3' read A
R70514.1 Clone IMAGE:142262 placenta 3' read
CF349948.1 placenta A
R70612.1 Clone IMAGE:142262 placenta 5' read
R71502.1 Clone IMAGE:142902 placenta 3' read A
R71555.1 Clone IMAGE:142902 placenta 5' read
R77180.1 Clone IMAGE:144111 placenta 5' read
R77961.1 Clone IMAGE:145764 placenta 3' read
R78335.1 Clone IMAGE:145764 placenta 5' read
CK906096.1 Clone IMAGE:5674838 pancreas 5' read
R81477.1 Clone IMAGE:147609 placenta 5' read P
H01988.1 Clone IMAGE:150676 placenta 3' read A
H02082.1 Clone IMAGE:150676 placenta 5' read
H04319.1 Clone IMAGE:149303 placenta 3' read
R68658.1 Clone IMAGE:139210 placenta 3' read
R68710.1 Clone IMAGE:139210 placenta 5' read P
BP321271.1 Clone PLR06506 placenta 5' read P
BE501917.1 Clone IMAGE:3185047 kidney 3' read A
BE677836.1 Clone IMAGE:3299383 mixed 3' read
BP394696.1 Clone hbt01624 pancreas 3' read
BP398745.1 Clone htp-55-92 pancreas 3' read A
BE765388.1 brain
BE784919.1 Clone IMAGE:3881843 lung 5' read
BE788935.1 Clone IMAGE:3883752 lung 5' read
BE767610.1 placenta
R92321.1 Clone IMAGE:195879 mixed 5' read
BE929257.1 placenta
BE929488.1 placenta P
BE929515.1 placenta
BE929549.1 placenta
BE930982.1 placenta
BE931064.1 placenta
BF085149.1 placenta
AV753382.1 Clone NPDBCH04 pituitary gland 5' read P
BF114764.1 Clone IMAGE:3391469 mixed 3' read
BF114823.1 Clone IMAGE:3391545 mixed 3' read A
H51275.1 Clone IMAGE:194031 mixed 3' read
H51848.1 Clone IMAGE:194031 mixed 5' read
BF196448.1 Clone IMAGE:3135382 kidney 3' read A
BF365042.1 brain
BF367086.1 placenta P
BF366974.1 placenta P
BF368342.1 placenta P
BF368781.1 placenta
DA101067.1 Clone BRACE3013107 brain 5' read P
DA537993.1 Clone FEKID2000710 kidney 5' read
DA521298.1 Clone FEBRA2011391 brain 5' read
H72471.1 Clone IMAGE:214062 mixed 5' read
BF061470.1 Clone IMAGE:3389843 mixed 3' read A
H72872.1 Clone IMAGE:214062 mixed 3' read A
DA843222.1 Clone PLACE6010862 placenta 5' read
DA843362.1 Clone PLACE6011041 placenta 5' read
BF431925.1 Clone IMAGE:3273858 mixed 3' read
DA852441.1 Clone PLACE7002404 placenta 5' read P
DA846436.1 Clone PLACE6014892 placenta 5' read
BF435151.1 Clone IMAGE:3268689 mixed 3' read
BF435840.1 Clone IMAGE:3268688 mixed 3' read
DA854075.1 Clone PLACE7004461 placenta 5' read P
DA854259.1 Clone PLACE7004694 placenta 5' read P
DA854273.1 Clone PLACE7004710 placenta 5' read
DA854784.1 Clone PLACE7005331 placenta 5' read
DA849517.1 Clone PLACE6018870 placenta 5' read
DA830253.1 Clone PLACE1004702 placenta 5' read
DA830630.1 Clone PLACE1005452 placenta 5' read
DA793778.1 Clone OCBBF2033931 brain 5' read
BF589540.1 Clone IMAGE:3254060 prostate 3' read P
DR979967.1 Clone ID_15439 placenta 3' read A
DA828179.1 Clone PLACE1000586 placenta 5' read
DA829360.1 Clone PLACE1002902 placenta 5' read
DB375339.1 Clone PLACE1004702 placenta 3' read A
DB375889.1 Clone PLACE1005452 placenta 3' read A
DB376335.1 Clone PLACE1006053 placenta 3' read A
DB372626.1 Clone PLACE1000586 placenta 3' read A
DB328535.1 Clone PLACE6011041 placenta 3' read A
DB328856.1 Clone PLACE7005331 placenta 3' read P
DB374150.1 Clone PLACE1002902 placenta 3' read A
BF771223.1 epididymis P
BF998868.1 placenta P
BG000795.1 placenta P
BG000921.1 placenta P
BG001260.1 placenta P
BG001261.1 placenta P
BG001463.1 placenta P
BG001950.1 placenta
BG001959.1 placenta
BG003085.1 placenta P
BG003883.1 placenta
BG004258.1 placenta P
BG004411.1 placenta
BG004593.1 placenta P
BG005163.1 placenta
BG006594.1 placenta P
BG006619.1 placenta
BG007083.1 placenta
BG008685.1 placenta
BG012201.1 placenta
BG012208.1 placenta
BG012209.1 placenta
BG014301.1 placenta P
BG015475.1 placenta P
BG015703.1 placenta P
BF985477.1 placenta P
BF985716.1 placenta P
BF986325.1 placenta
BF987012.1 placenta
BF987740.1 placenta
BF987743.1 placenta
BF987746.1 placenta
BF987938.1 placenta
BF988653.1 placenta
BF988858.1 placenta
BF988860.1 placenta P
BF988867.1 placenta
BF988919.1 placenta
BF988922.1 placenta P
BF988928.1 placenta P
BF988952.1 placenta P
BF988953.1 placenta P
BF989071.1 placenta
BF989135.1 placenta
BF989318.1 placenta P
BF989325.1 placenta P
BF989327.1 placenta P
BF989332.1 placenta
BF989334.1 placenta P
BF989793.1 placenta
BF990233.1 placenta
BF990262.1 placenta
BF990643.1 placenta P
BF991167.1 placenta
BF992342.1 placenta
BF992375.1 placenta P
BF993980.1 placenta P
BF994393.1 placenta P
BF995158.1 placenta P
BF995327.1 placenta
BF995336.1 placenta
BF995650.1 placenta P
BF995812.1 placenta
BF995964.1 placenta P
BF996402.1 placenta P
BF996614.1 placenta
BF958351.1 brain
AL538708.3 Clone CS0DF037YH10 brain 5' read
AL554447.3 Clone CS0DI084YF21 placenta 5' read P
N30053.1 Clone IMAGE:258599 placenta 3' read
N30722.1 Clone IMAGE:257424 placenta 3' read
AL567462.3 Clone CS0DF037YH10 brain 3' read
AL577141.1 Clone CS0DI084YF21 placenta 3' read P
BG354569.1 Clone 200386 placenta
N41334.1 Clone IMAGE:257424 placenta 5' read
BG434754.1 Clone IMAGE:4604942 placenta 5' read
BG436219.1 Clone IMAGE:4605753 placenta 5' read
BG436383.1 Clone IMAGE:4619435 placenta 5' read
BG570905.1 Clone IMAGE:4714116 placenta 5' read
BG571874.1 Clone IMAGE:4720565 placenta 5' read
BG572482.1 Clone IMAGE:4721073 placenta 5' read A
BG572831.1 Clone IMAGE:4721707 placenta 5' read
N49277.1 Clone IMAGE:280389 brain 3' read A
BG623398.1 Clone IMAGE:4770178 placenta 5' read
BI048360.1 stomach
BI050091.1 placenta
BI050099.1 placenta
BI051442.1 placenta
BI052094.1 placenta
BI052274.1 placenta
BI052339.1 placenta
BI052698.1 placenta
BI052703.1 placenta P
BI054365.1 placenta
BI054761.1 placenta
BI057213.1 placenta P
BI058131.1 placenta
ES313666.1 skin P
EL948261.1 eye 5' read
BM127457.1 Clone IMAGE:5674838 pancreas 5' read
BM682425.1 Clone UI-E-EJ0-aio-c-17-0-UI eye 3' read A
BM723192.1 Clone UI-E-EJ0-aio-c-17-0-UI eye 5' read A
BM726954.1 Clone UI-E-EJ0-air-j-07-0-UI eye 5' read
W79312.1 Clone IMAGE:346954 heart 5' read
W79393.1 Clone IMAGE:346954 heart 3' read A
AL710559.1 Clone DKFZp686M146 muscle 5' read P
BQ012383.1 Clone UI-1-BC1p-asn-g-09-0-UI placenta 3' read A
BQ012877.1 Clone UI-1-BC1-asn-g-09-0-UI placenta 3' read A
BQ021951.1 Clone UI-1-BB0-acw-f-06-0-UI placenta 3' read A
BQ028475.1 Clone IMAGE:3107110 uncharacterized tissue 3' read A
T53732.1 Clone IMAGE:69043 placenta 5' read
BQ184681.1 Clone UI-E-EJ1-ajn-c-08-0-UI eye 3' read A
BQ186109.1 Clone UI-E-EJ1-ajn-c-08-0-UI eye 5' read A
BQ188495.1 Clone UI-E-EJ1-ajw-d-16-0-UI eye 5' read A
AA004923.1 Clone IMAGE:428464 mixed 5' read
AA004924.1 Clone IMAGE:428464 mixed 3' read A
AA005343.1 Clone IMAGE:428488 mixed 5' read
AA005344.1 Clone IMAGE:428488 mixed 3' read
T54319.1 Clone IMAGE:69044 placenta 3' read
T54325.1 Clone IMAGE:69043 placenta 3' read
BQ365045.1 placenta P
BQ365362.1 placenta
BQ368023.1 placenta P
BQ368379.1 placenta
BQ370355.1 placenta
BQ370373.1 placenta
BQ370804.1 placenta
BQ370902.1 placenta
BQ433015.1 Clone IMAGE:6010297 lung 5' read
AA040640.1 Clone IMAGE:487328 uterus 5' read
AA043125.1 Clone IMAGE:486172 uterus 3' read A
AA043602.1 Clone IMAGE:486172 uterus 5' read
AA045517.1 Clone IMAGE:487328 uterus 3' read A
AA046497.1 Clone IMAGE:488357 uterus 3' read A
AA046769.1 Clone IMAGE:488357 uterus 5' read
AA047826.1 Clone IMAGE:380308 eye 3' read A
AA047852.1 Clone IMAGE:380304 eye 5' read
AA058945.1 Clone IMAGE:512480 eye 3' read A
AA059406.1 Clone IMAGE:512480 eye 5' read
AA121913.1 Clone IMAGE:566180 eye 5' read
AA136839.1 Clone IMAGE:491102 uterus 3' read A
AA136995.1 Clone IMAGE:491102 uterus 5' read
AA151581.1 Clone IMAGE:503142 uterus 3' read
AA149397.1 Clone IMAGE:503142 uterus 5' read
BU633638.1 Clone UI-H-FL1-bgv-e-22-0-UI bone 3' read A
AA233323.1 Clone IMAGE:668701 mixed 5' read
AA233324.1 Clone IMAGE:668701 mixed 3' read A
BU741222.1 Clone UI-E-EJ0-air-j-07-0-UI eye 3' read A
BU752022.1 Clone UI-1-BB0-acz-d-12-0-UI placenta 3' read A
BU752090.1 Clone UI-1-BB0-adf-c-12-0-UI placenta 3' read A
BU929245.1 Clone IMAGE:6663038 placenta 5' read
BU929761.1 Clone IMAGE:6663783 placenta 5' read
AA257076.1 Clone IMAGE:682188 mixed 3' read
AA256967.1 Clone IMAGE:682188 mixed 5' read
CA429458.1 Clone UI-H-FH1-bfm-j-05-0-UI bone 3' read A
AA367560.1 placenta
AA367643.1 placenta
AA367644.1 placenta A
AA367785.1 placenta A
AA367756.1 placenta
AA368081.1 placenta
AA368226.1 placenta P
AA368801.1 placenta
T89460.1 Clone IMAGE:116764 mixed 3' read A
T89548.1 Clone IMAGE:116764 mixed 5' read
AA496709.1 Clone IMAGE:897357 kidney 3' read
AA496765.1 Clone IMAGE:897355 kidney 5' read
AA625494.1 Clone IMAGE:1047314 mixed 5' read
AA682228.1 Clone 1293107 testis 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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