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UGID:158392     UniGene Hs.173716     Homo sapiens (human)   ADAM33
ADAM metallopeptidase domain 33 (ADAM33)

Human protein-coding gene ADAM33. Represented by 219 ESTs from 44 cDNA libraries. EST representation biased toward blastocyst. Corresponds to 2 reference sequences (different isoforms). [UniGene 158392 - Hs.173716]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_079496.1 ADAM33 gene product H. sapiens 100.0 812
NP_291093.2 Adam33 gene product M. musculus 74.3 782
XP_693712.5 PREDICTED: disintegrin and metalloproteinase domain-containing protein 19 D. rerio 56.5 685
NP_001080914.1 ADAM metallopeptidase domain 33 X. laevis 55.1 737
Other hits (2 of 28) [Show all]SpeciesId(%)Len(aa)
XP_514485.3 PREDICTED: disintegrin and metalloproteinase domain-containing protein 33 P. troglodytes 97.9 620
XP_003905059.1 PREDICTED: LOW QUALITY PROTEIN: disintegrin and metalloproteinase domain-containing protein 33 P. anubis 93.5 811

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: blastocyst [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uterus; uncharacterized tissue; brain; testis; skin; pancreas; placenta; thymus; mouth; trachea; embryonic tissue; vascular; adipose tissue; prostate; muscle; thyroid; mixed; lung; ganglia; stomach; nerve; eye
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 20
Map position: 20p13
UniSTS entry: Chr 20 PMC196627P2
UniSTS entry: Chr 20 PMC196627P4
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (23)

AY223855.1 Homo sapiens clone 6 a disintegrin and metalloprotease 33 mRNA, partial cds P
AY223854.1 Homo sapiens clone 5 a disintegrin and metalloprotease 33 mRNA, partial cds P
AY223853.1 Homo sapiens clone 4 a disintegrin and metalloprotease 33 mRNA, partial cds
AY223852.1 Homo sapiens clone 3 a disintegrin and metalloprotease 33 mRNA, partial cds P
AY223851.1 Homo sapiens clone 2 a disintegrin and metalloprotease 33 mRNA, partial cds P
AY223850.1 Homo sapiens clone 1 a disintegrin and metalloprotease 33 mRNA, partial cds P
AK126498.1 Homo sapiens cDNA FLJ44534 fis, clone UTERU3004616 P
AK126487.1 Homo sapiens cDNA FLJ44523 fis, clone UTERU3003116 P
AK123015.1 Homo sapiens cDNA FLJ16827 fis, clone UTERU3011273, moderately similar to ADAM 12 precursor (EC 3.4.24.-) P
AY358314.1 Homo sapiens clone DNA76788 Adam33 (UNQ873) mRNA, complete cds PA
BC062663.1 Homo sapiens ADAM metallopeptidase domain 33, mRNA (cDNA clone IMAGE:30405083), complete cds PA
AK226148.1 Homo sapiens mRNA for ADAM metallopeptidase domain 33 isoform beta preproprotein variant, clone: ah04724 P
BC125112.1 Homo sapiens ADAM metallopeptidase domain 33, mRNA (cDNA clone IMAGE:40118830), complete cds P
BC125113.1 Homo sapiens ADAM metallopeptidase domain 33, mRNA (cDNA clone MGC:149823 IMAGE:40118831), complete cds P
AB055891.1 Homo sapiens ADAM33 mRNA for metalloprotease disintegrin, complete cds P
NM_025220.2 Homo sapiens ADAM metallopeptidase domain 33 (ADAM33), transcript variant 1, mRNA PA
AF466287.1 Homo sapiens tissue-type uterus a disintegrin and metalloprotease domain 33 (ADAM33) mRNA, complete cds PA
AK095953.1 Homo sapiens cDNA FLJ38634 fis, clone HHDPC2001432, weakly similar to ADAM 12 PRECURSOR (EC 3.4.24.-) P
AK092627.1 Homo sapiens cDNA FLJ35308 fis, clone PROST2009909 P
AK300429.1 Homo sapiens cDNA FLJ60155 complete cds, highly similar to ADAM 33 precursor (EC 3.4.24.-) (Adisintegrin and metalloproteinase domain 33) P
AK304037.1 Homo sapiens cDNA FLJ54728 complete cds, highly similar to ADAM 33 precursor (EC 3.4.24.-) (Adisintegrin and metalloproteinase domain 33) P
AF466289.1 Homo sapiens tissue-type whole lung a disintegrin and metalloprotease domain 33 (ADAM33) mRNA, 5' UTR and partial cds
NM_153202.1 Homo sapiens ADAM metallopeptidase domain 33 (ADAM33), transcript variant 2, mRNA PA

EST sequences (219)

R23385.1 Clone IMAGE:131485 placenta 5' read
BX103461.1 Clone IMAGp998L14182_;_IMAGE:131485 placenta A
AI635622.1 Clone IMAGE:2289183 uterus 3' read A
CB269146.1 adipose tissue 5' read
CD172502.1 Clone IMAGE:30375755 brain 5' read
CD299381.1 Clone IMAGE:30405083 vascular 5' read
CD511532.1 Clone IMAGE:30405880 vascular 5' read
CD558327.1 Clone IMAGE:30396702 brain 5' read
AW131070.1 Clone IMAGE:2622123 stomach 3' read A
CF125127.1 Clone IMAGE:30558469 lung 5' read P
CD632562.1 uncharacterized tissue
CD632563.1 uncharacterized tissue
CD632564.1 uncharacterized tissue
CD632565.1 uncharacterized tissue
CD632566.1 uncharacterized tissue
CD632574.1 uncharacterized tissue
CD632575.1 uncharacterized tissue
CD632576.1 uncharacterized tissue
CD632577.1 uncharacterized tissue
CD632578.1 uncharacterized tissue
CD632579.1 uncharacterized tissue P
CD632580.1 uncharacterized tissue P
CD632581.1 uncharacterized tissue
CD632582.1 uncharacterized tissue
CD632590.1 uncharacterized tissue
CD632591.1 uncharacterized tissue
CD632592.1 uncharacterized tissue
CD632593.1 uncharacterized tissue
CD632594.1 uncharacterized tissue
CD632595.1 uncharacterized tissue
CD632596.1 uncharacterized tissue
CD632567.1 uncharacterized tissue
CD632568.1 uncharacterized tissue
CD632569.1 uncharacterized tissue
CD632570.1 uncharacterized tissue
CD632571.1 uncharacterized tissue
CD632572.1 uncharacterized tissue
CD632573.1 uncharacterized tissue
CD632583.1 uncharacterized tissue
CD632584.1 uncharacterized tissue
CD632585.1 uncharacterized tissue
CD632586.1 uncharacterized tissue
CD632587.1 uncharacterized tissue
CD632588.1 uncharacterized tissue P
CD632589.1 uncharacterized tissue
AW594247.1 Clone IMAGE:2949663 uncharacterized tissue 3' read A
AW796671.1 uterus
CK823842.1 Clone IMAGE:5634087 pancreas 3' read
CK823843.1 Clone IMAGE:5634087 pancreas 5' read
CN402132.1 embryonic tissue 5' read P
CN402131.1 embryonic tissue 5' read
CX781322.1 Clone IMAGE:30928969 embryonic tissue 5' read P
DR007214.1 Clone TC123902 testis 5' read P
BF091806.1 testis
DA240428.1 Clone BRAWH3037978 brain 5' read P
DA195557.1 Clone BRAMY4001028 brain 5' read P
DA321722.1 Clone BRHIP3015056 brain 5' read P
DA126587.1 Clone BRACE3049617 brain 5' read P
DA238582.1 Clone BRAWH3035756 brain 5' read P
DA239497.1 Clone BRAWH3036855 brain 5' read P
DA214975.1 Clone BRAWH3005201 brain 5' read P
DA327247.1 Clone BRHIP3023097 brain 5' read P
DA184999.1 Clone BRAMY3003939 brain 5' read P
DA191330.1 Clone BRAMY3014192 brain 5' read P
DA218378.1 Clone BRAWH3009532 brain 5' read P
DA107186.1 Clone BRACE3021841 brain 5' read P
DA108934.1 Clone BRACE3025308 brain 5' read P
DA574470.1 Clone HHDPC2001432 skin 5' read P
BF855368.1 prostate
DA453701.1 Clone CTONG2026682 mouth 5' read P
DB043367.1 Clone TESTI2031040 testis 5' read
DA862115.1 Clone PLACE7015123 placenta 5' read P
DA857183.1 Clone PLACE7008410 placenta 5' read P
DA872842.1 Clone PROST2009909 prostate 5' read P
DB146179.1 Clone THYMU3021306 thymus 5' read P
DB225158.1 Clone TRACH3016959 trachea 5' read P
DB226968.1 Clone TRACH3019318 trachea 5' read P
DB351604.1 Clone UTERU2017623 uterus 3' read A
DB273211.1 Clone UTERU2035743 uterus 5' read P
DB162932.1 Clone THYMU3044049 thymus 5' read P
DB280083.1 Clone UTERU3006649 uterus 5' read P
DB280088.1 Clone UTERU3006656 uterus 5' read P
DB280110.1 Clone UTERU3006680 uterus 5' read P
DB352335.1 Clone UTERU3004616 uterus 3' read A
DB280218.1 Clone UTERU3006821 uterus 5' read P
DB280306.1 Clone UTERU3006931 uterus 5' read
DB280406.1 Clone UTERU3007056 uterus 5' read P
DB352648.1 Clone UTERU3011273 uterus 3' read A
DB281114.1 Clone UTERU3007971 uterus 5' read P
DB281312.1 Clone UTERU3008241 uterus 5' read P
DB281536.1 Clone UTERU3008523 uterus 5' read P
DB079816.1 Clone TESTI4025152 testis 5' read P
DB281817.1 Clone UTERU3008879 uterus 5' read P
DB275451.1 Clone UTERU3000489 uterus 5' read
DB275482.1 Clone UTERU3000534 uterus 5' read P
DB275632.1 Clone UTERU3000729 uterus 5' read P
DB275863.1 Clone UTERU3001041 uterus 5' read P
DB282322.1 Clone UTERU3009529 uterus 5' read P
DB282404.1 Clone UTERU3009628 uterus 5' read P
DB282415.1 Clone UTERU3009643 uterus 5' read P
DB276108.1 Clone UTERU3001386 uterus 5' read P
DB276130.1 Clone UTERU3001413 uterus 5' read P
DB276178.1 Clone UTERU3001487 uterus 5' read P
DB282832.1 Clone UTERU3010217 uterus 5' read P
DB276705.1 Clone UTERU3002173 uterus 5' read P
DB237197.1 Clone TRACH3032769 trachea 5' read P
DB283006.1 Clone UTERU3010459 uterus 5' read P
DB283166.1 Clone UTERU3010690 uterus 5' read P
DB283251.1 Clone UTERU3010795 uterus 5' read P
DB283253.1 Clone UTERU3010798 uterus 5' read P
DB283258.1 Clone UTERU3010804 uterus 5' read P
DB277021.1 Clone UTERU3002569 uterus 5' read P
DB283621.1 Clone UTERU3011273 uterus 5' read P
DB283768.1 Clone UTERU3011456 uterus 5' read
DB283855.1 Clone UTERU3011568 uterus 5' read P
DB277400.1 Clone UTERU3003043 uterus 5' read P
DB277411.1 Clone UTERU3003059 uterus 5' read P
DB277437.1 Clone UTERU3003090 uterus 5' read P
DB277459.1 Clone UTERU3003116 uterus 5' read
DB277952.1 Clone UTERU3003799 uterus 5' read P
DB061353.1 Clone TESTI4001190 testis 5' read P
DB290121.1 Clone UTERU3020045 uterus 5' read P
DB290163.1 Clone UTERU3020100 uterus 5' read P
DB284050.1 Clone UTERU3011819 uterus 5' read P
DB290684.1 Clone UTERU3020783 uterus 5' read P
DB284161.1 Clone UTERU3011977 uterus 5' read P
DB290794.1 Clone UTERU3020922 uterus 5' read P
DB284605.1 Clone UTERU3012592 uterus 5' read P
DB278180.1 Clone UTERU3004114 uterus 5' read P
DB278223.1 Clone UTERU3004182 uterus 5' read P
DB278300.1 Clone UTERU3004276 uterus 5' read P
DB278371.1 Clone UTERU3004371 uterus 5' read P
DB278556.1 Clone UTERU3004616 uterus 5' read P
DB278623.1 Clone UTERU3004710 uterus 5' read P
DB278868.1 Clone UTERU3005015 uterus 5' read
DB278901.1 Clone UTERU3005060 uterus 5' read P
DB291006.1 Clone UTERU3021236 uterus 5' read P
DB330013.1 Clone PROST2009909 prostate 3' read A
DB291335.1 Clone UTERU3021688 uterus 5' read P
DB291497.1 Clone UTERU3021906 uterus 5' read P
DB285006.1 Clone UTERU3013122 uterus 5' read P
DB291622.1 Clone UTERU3022069 uterus 5' read P
DB285117.1 Clone UTERU3013262 uterus 5' read P
DB285267.1 Clone UTERU3013449 uterus 5' read P
DB291846.1 Clone UTERU3022361 uterus 5' read P
DB285502.1 Clone UTERU3013773 uterus 5' read P
DB285629.1 Clone UTERU3013941 uterus 5' read P
DB285669.1 Clone UTERU3013993 uterus 5' read P
DB285710.1 Clone UTERU3014046 uterus 5' read P
DB279171.1 Clone UTERU3005439 uterus 5' read P
DB285797.1 Clone UTERU3014161 uterus 5' read P
DB279237.1 Clone UTERU3005527 uterus 5' read P
DB279323.1 Clone UTERU3005636 uterus 5' read P
DB285913.1 Clone UTERU3014319 uterus 5' read P
DB285986.1 Clone UTERU3014420 uterus 5' read P
DB279423.1 Clone UTERU3005773 uterus 5' read
DB279486.1 Clone UTERU3005855 uterus 5' read P
DB279652.1 Clone UTERU3006071 uterus 5' read P
DB318936.1 Clone HHDPC2001432 skin 3' read
DB292047.1 Clone UTERU3022642 uterus 5' read P
DB063480.1 Clone TESTI4003952 testis 5' read P
DB292248.1 Clone UTERU3022915 uterus 5' read P
DB292612.1 Clone UTERU3023419 uterus 5' read P
DB286536.1 Clone UTERU3015162 uterus 5' read P
DB286668.1 Clone UTERU3015335 uterus 5' read P
DB286740.1 Clone UTERU3015435 uterus 5' read P
DB220359.1 Clone TRACH3010677 trachea 5' read P
DB214684.1 Clone TRACH3003132 trachea 5' read P
DB064030.1 Clone TESTI4004683 testis 5' read P
DB064910.1 Clone TESTI4005817 testis 5' read P
DB287030.1 Clone UTERU3015828 uterus 5' read P
DB287048.1 Clone UTERU3015852 uterus 5' read P
DB260306.1 Clone UTERU2017623 uterus 5' read
DB287214.1 Clone UTERU3016084 uterus 5' read P
DB287342.1 Clone UTERU3016257 uterus 5' read P
DB287387.1 Clone UTERU3016311 uterus 5' read P
DB287694.1 Clone UTERU3016715 uterus 5' read P
DB287835.1 Clone UTERU3016887 uterus 5' read P
DB287863.1 Clone UTERU3016932 uterus 5' read P
DB287950.1 Clone UTERU3017051 uterus 5' read P
DB065841.1 Clone TESTI4007015 testis 5' read P
DB288096.1 Clone UTERU3017251 uterus 5' read P
DB288205.1 Clone UTERU3017390 uterus 5' read P
DB099139.1 Clone TESTI4050783 testis 5' read P
DB289252.1 Clone UTERU3018822 uterus 5' read P
DB289838.1 Clone UTERU3019670 uterus 5' read P
DB289895.1 Clone UTERU3019746 uterus 5' read P
DB223230.1 Clone TRACH3014467 trachea 5' read P
BF990485.1 placenta
F19469.2 Clone NOTAVAIL04072 muscle
BI004270.1 thyroid
EL736607.1 mixed 5' read P
ES309184.1 skin P
ES310548.1 skin P
ES310668.1 skin P
DC422172.1 Clone UTERU3000050 uterus 5' read P
DC422678.1 Clone UTERU3006255 uterus 5' read P
DC422776.1 Clone UTERU3007649 uterus 5' read P
DC422859.1 Clone UTERU3008614 uterus 5' read P
DC415596.1 Clone TRACH3003287 trachea 5' read P
DC400361.1 Clone TESTI4005124 testis 5' read P
DC334883.1 Clone BRHIP3027748 brain 5' read P
BI826766.1 Clone IMAGE:5169013 brain 5' read
BM510563.1 Clone IMAGE:5634087 pancreas 3' read A
BM511392.1 Clone IMAGE:5634087 pancreas 5' read
BQ694108.1 adipose tissue 5' read P
BQ880218.1 Clone IMAGE:6185898 ganglia 5' read
BQ922126.1 Clone IMAGE:6201261 nerve 5' read
BU150601.1 Clone IMAGE:6178372 ganglia 5' read P
AA197050.1 Clone IMAGE:608906 eye 5' read
BU783941.1 Clone IMAGE:6124276 pancreas 3' read
BU784209.1 Clone IMAGE:6124276 pancreas 5' read
HY000187.1 Clone H04D001J03 testis P
HY017503.1 Clone H04D059G19 testis P
HY021179.1 Clone H04D071J09 testis P
HY023475.1 Clone H04D080C04 testis P
HY204230.1 Clone H04D071J09 testis P
AA442551.1 Clone IMAGE:759465 embryonic tissue 5' read P
T98408.1 Clone IMAGE:122092 mixed 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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