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UGID:154191     UniGene Hs.153381     Homo sapiens (human)   DARC
Duffy blood group, chemokine receptor (DARC)

Human protein-coding gene DARC. Represented by 149 ESTs from 72 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 154191 - Hs.153381]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001116423.1 DARC gene product H. sapiens 100.0 337
NP_034175.2 Duffy antigen/chemokine receptor M. musculus 65.0 333
Other hits (2 of 11) [Show all]SpeciesId(%)Len(aa)
XP_001170585.1 PREDICTED: Duffy antigen/chemokine receptor isoform 2 P. troglodytes 99.4 337
XP_003892935.1 PREDICTED: Duffy antigen/chemokine receptor P. anubis 96.1 335

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; pharynx; mixed; mammary gland; vascular; uncharacterized tissue; kidney; placenta; pancreas; testis; eye; cervix; intestine; uterus; heart; thymus; ovary; parathyroid; connective tissue; larynx; bone; adipose tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q21-q22
UniSTS entry: Chr 1 RH70526 [Map Viewer]
UniSTS entry: Chr 1 IB2132 [Map Viewer]
UniSTS entry: Chr 1 PMC24175P1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

BX537430.1 Homo sapiens mRNA; cDNA DKFZp686D15198 (from clone DKFZp686D15198); complete cds PA
NM_002036.3 Homo sapiens Duffy blood group, chemokine receptor (DARC), transcript variant 2, mRNA PA
U01839.1 Human Duffy blood group antigen (Fya-b+) mRNA, complete cds P
AF030521.1 Homo sapiens Duffy blood group antigen mRNA, complete cds P
BC095496.1 Homo sapiens Duffy blood group, chemokine receptor, mRNA (cDNA clone IMAGE:6912772), partial cds P
BC017817.1 Homo sapiens Duffy blood group, chemokine receptor, mRNA (cDNA clone MGC:22402 IMAGE:4696425), complete cds PA
AK291593.1 Homo sapiens cDNA FLJ75122 complete cds, highly similar to Homo sapiens Duffy blood group, chemokine receptor, mRNA PA
AK309521.1 Homo sapiens cDNA, FLJ99562 P
NM_001122951.2 Homo sapiens Duffy blood group, chemokine receptor (DARC), transcript variant 1, mRNA PA
HE572751.1 Homo sapiens partial mRNA for duffy blood group chemokine receptor (DARC gene), allele S326F P
JX081310.1 Homo sapiens Duffy antigen chemokine receptor (DARC) mRNA, complete cds P
AY167991.1 Homo sapiens Duffy antigen (FY) mRNA, FY-B allele, complete cds P

EST sequences (149)

AI031548.1 Clone IMAGE:1650048 parathyroid 3' read PA
AI092154.1 Clone IMAGE:1694171 heart 3' read PA
AI094929.1 Clone IMAGE:1687126 brain 3' read PA
T26349.1 thymus
AI290303.1 Clone IMAGE:1880589 mixed 3' read P
AI318397.1 Clone IMAGE:1912256 intestine 3' read PA
AI342118.1 Clone IMAGE:1949075 uterus 3' read PA
AI342121.1 Clone IMAGE:1949081 uterus 3' read PA
AI358998.1 Clone IMAGE:2013006 brain 3' read PA
T15925.1 brain 3' read A
AI367298.1 Clone IMAGE:1933093 mixed 3' read PA
AI479828.1 Clone IMAGE:2163419 brain 3' read PA
AI493965.1 Clone IMAGE:2030493 kidney 3' read PA
AI568490.1 Clone IMAGE:2170045 brain 3' read PA
AI766342.1 Clone IMAGE:2385141 kidney 3' read A
AI769588.1 Clone IMAGE:2403814 kidney 3' read PA
BX281058.1 Clone IMAGp998G026739_;_IMAGE:2698393 cervix P
CB959180.1 Clone IMAGE:30351405 mixed 5' read P
CD246179.1 Clone IMAGE:6912772 mixed 5' read P
CD357725.1 Clone IMAGE:30404418 vascular 5' read P
CD359452.1 Clone IMAGE:30386752 testis 5' read P
CD515324.1 Clone IMAGE:30407967 brain 5' read P
AW016922.1 Clone IMAGE:2711970 uncharacterized tissue 3' read PA
CD558729.1 Clone IMAGE:30395349 brain 5' read P
AW024541.1 Clone IMAGE:2526029 kidney 3' read PA
CD687551.1 pharynx P
CD689657.1 pharynx P
CD690012.1 pharynx P
CD687159.1 pharynx P
CD691132.1 pharynx P
CD692448.1 pharynx P
CD695692.1 pharynx P
CD696862.1 pharynx P
CD698026.1 pharynx
CD699515.1 pharynx P
CD701182.1 pharynx P
CD708221.1 pharynx P
CD703172.1 pharynx P
CD705125.1 pharynx
CD705202.1 pharynx P
CD709396.1 pharynx P
AW166473.1 Clone IMAGE:2697455 cervix 3' read PA
AW170565.1 Clone IMAGE:2698393 cervix 3' read PA
F11127.1 Clone c-3ac12 brain 3' read A
AW340869.1 Clone IMAGE:2873558 kidney 3' read PA
AW351464.1 mammary gland
R73130.1 Clone IMAGE:156103 mammary gland 3' read
R73187.1 Clone IMAGE:156103 mammary gland 5' read P
AW974081.1 uncharacterized tissue P
H11752.1 Clone IMAGE:47806 brain 3' read
H11831.1 Clone IMAGE:47806 brain 5' read
H14638.1 Clone IMAGE:159395 mammary gland 3' read A
H14932.1 Clone IMAGE:159395 mammary gland 5' read
BE222481.1 Clone IMAGE:3180815 lung 3' read P
CO929812.1 Clone IMAGE:7211816 mixed 3' read P
CO933343.1 Clone IMAGE:7262024 mixed 5' read P
CO933366.1 Clone IMAGE:7262024 mixed 3' read
BP317883.1 Clone PCD05953 heart 5' read P
BP319196.1 Clone PCD09429 heart 5' read P
BP319514.1 Clone PCD11042 heart 5' read P
BP329032.1 Clone RCT02325 intestine 5' read P
BP330579.1 Clone RCT06885 intestine 5' read P
BP346568.1 Clone SZB00566 brain 5' read P
CV373019.1 lung
CV373081.1 lung
CV373715.1 placenta
CV373851.1 placenta
CV374065.1 placenta
BE467284.1 Clone IMAGE:3212709 lung 3' read P
BE502006.1 Clone IMAGE:3196973 uncharacterized tissue 3' read PA
BE504071.1 Clone IMAGE:3211284 lung 3' read P
H30166.1 Clone IMAGE:182134 mammary gland 5' read P
H30181.1 Clone IMAGE:182228 mammary gland 5' read
BP386093.1 Clone hbt04609 pancreas 3' read P
BP387003.1 Clone hbt06487 pancreas 3' read P
H39902.1 Clone IMAGE:181704 mammary gland 5' read
DN993684.1 Clone TC125243 brain 5' read P
BE939059.1 testis
T27909.1 eye 5' read
DA079970.1 Clone BRACE2032943 brain 5' read
DA348240.1 Clone BRSSN2009990 brain 5' read
DA060713.1 Clone BRACE2009082 brain 5' read
DA055409.1 Clone BRACE2001436 brain 5' read
DA065480.1 Clone BRACE2014902 brain 5' read
DA065676.1 Clone BRACE2015142 brain 5' read
DA065725.1 Clone BRACE2015207 brain 5' read
DA065757.1 Clone BRACE2015246 brain 5' read
DA059891.1 Clone BRACE2008028 brain 5' read
DA069161.1 Clone BRACE2019474 brain 5' read
DA077416.1 Clone BRACE2029758 brain 5' read
BF852236.1 lung P
DA584914.1 Clone HLUNG2005003 lung 5' read
DA591572.1 Clone HLUNG2013804 lung 5' read P
DA513608.1 Clone FEBRA2001029 brain 5' read
DA592014.1 Clone HLUNG2014354 lung 5' read P
DA520849.1 Clone FEBRA2010816 brain 5' read
DA593126.1 Clone HLUNG2015741 lung 5' read P
DA593623.1 Clone HLUNG2016362 lung 5' read P
DA483687.1 Clone FCBBF2000073 brain 5' read
DA595249.1 Clone HLUNG2018412 lung 5' read P
DA774161.1 Clone OCBBF2007789 brain 5' read
DA849450.1 Clone PLACE6018793 placenta 5' read
DB024278.1 Clone TESTI2005766 testis 5' read
DB273974.1 Clone UTERU2036807 uterus 5' read P
DB366923.1 Clone NT2RP2005952 testis 3' read PA
DB327991.1 Clone PLACE5000012 placenta 3' read PA
BF939778.1 Clone IMAGE:3440923 brain 3' read PA
BG507061.1 Clone IMAGE:4071072 lung 5' read
BG548238.1 Clone IMAGE:4703446 lung 5' read
BG539935.1 Clone IMAGE:4692082 lung 5' read P
BG541700.1 Clone IMAGE:4695763 lung 5' read P
BG542543.1 Clone IMAGE:4696425 lung 5' read P
N62732.1 Clone IMAGE:289022 brain 3' read A
BG991498.1 larynx P
N78456.1 Clone IMAGE:289022 brain 5' read P
EL735542.1 mixed 5' read P
BI488438.1 Clone IMAGE:5191760 brain 5' read
EL948881.1 eye 5' read P
BI819401.1 Clone IMAGE:5175619 mixed 5' read P
BM671230.1 Clone UI-E-CQ1-agc-m-12-0-UI brain 3' read PA
BM697018.1 Clone UI-E-DW0-agl-n-14-0-UI eye 5' read
BM702006.1 Clone UI-E-CQ1-aex-l-16-0-UI brain 5' read P
BM702895.1 Clone UI-E-CK1-afi-e-15-0-UI eye 5' read P
BM708111.1 Clone UI-E-CI1-aft-j-03-0-UI eye 5' read P
BM710069.1 Clone UI-E-CQ1-agc-m-12-0-UI brain 5' read P
BM725971.1 Clone UI-E-EJ0-aih-f-20-0-UI eye 5' read PA
BM972973.1 Clone UI-CF-EC1-abt-a-16-0-UI lung 3' read PA
BM990686.1 Clone IMAGE:5863338 lung 3' read PA
BM998664.1 Clone IMAGE:5886118 connective tissue 3' read PA
BQ333184.1 lung
FN124949.1 Clone 183650_2442_3967
FN062887.1 Clone 022871_2350_2710
BU683321.1 Clone UI-CF-EC1-ace-m-14-0-UI lung 3' read PA
BU729667.1 Clone UI-E-CQ1-aey-l-16-0-UI brain 3' read PA
BU729842.1 Clone UI-E-CK1-afi-e-15-0-UI eye 3' read PA
BU731963.1 Clone UI-E-CI1-aft-j-03-0-UI eye 3' read PA
AA284947.1 Clone IMAGE:713954 ovary 3' read PA
AA285100.1 Clone IMAGE:713954 ovary 5' read
CA425659.1 Clone UI-H-FE1-bdy-p-24-0-UI bone 3' read PA
CA435450.1 Clone UI-H-DT0-atu-o-15-0-UI connective tissue 3' read PA
T74141.1 Clone IMAGE:22411 brain 5' read
T82477.1 Clone IMAGE:22411 brain 3' read A
M78802.1 Clone HHCMF86 brain P
AA482092.1 Clone IMAGE:756284 ovary 3' read PA
AA480120.1 Clone IMAGE:756284 ovary 5' read P
AA568867.1 Clone IMAGE:1061384 adipose tissue P
AA724903.1 Clone 1341603 parathyroid 3' read A
AA855034.1 Clone IMAGE:1401824 parathyroid 3' read PA
AA916897.1 Clone IMAGE:1441781 mammary gland 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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