> Uncoupling protein 3 (mitochondrial, proton carrier) (UCP3)
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UGID:142919     UniGene Hs.101337     Homo sapiens (human)   UCP3 Order cDNA clone, Links
Uncoupling protein 3 (mitochondrial, proton carrier) (UCP3)

Human protein-coding gene UCP3. Represented by 44 ESTs from 30 cDNA libraries. EST representation biased toward adult. Corresponds to 2 reference sequences (different isoforms). [UniGene 142919 - Hs.101337]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003347.1 UCP3 gene product H. sapiens 100.0 311
NP_033490.1 Ucp3 gene product M. musculus 85.7 307
NP_001080223.1 uncoupling protein 2 (mitochondrial, proton carrier) X. laevis 73.3 306
NP_571251.1 ucp2 gene product D. rerio 71.5 309
NP_190979.1 uncoupling mitochondrial protein 1 A. thaliana 48.1 295
XP_001695417.1 uncoupling protein C. reinhardtii 47.3 292
Other hits (2 of 46) [Show all]SpeciesId(%)Len(aa)
XP_001174875.1 PREDICTED: mitochondrial uncoupling protein 3 isoform 4 P. troglodytes 99.0 311
XP_001115599.1 PREDICTED: mitochondrial uncoupling protein 3 M. mulatta 96.5 311

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uncharacterized tissue; muscle; lung; mammary gland; testis; heart; uterus; prostate; mouth; liver; blood; spinal cord; eye; mixed; connective tissue; brain; vascular; intestine; embryonic tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q13.4
UniSTS entry: UCP3
UniSTS entry: Chr 11 RH65723 [Map Viewer]
UniSTS entry: Chr 11 D11S2240E [Map Viewer]
UniSTS entry: Chr 11 D11S2239E [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

NM_003356.3 Homo sapiens uncoupling protein 3 (mitochondrial, proton carrier) (UCP3), nuclear gene encoding mitochondrial protein, transcript variant long, mRNA PA
NM_022803.2 Homo sapiens uncoupling protein 3 (mitochondrial, proton carrier) (UCP3), nuclear gene encoding mitochondrial protein, transcript variant short, mRNA PA
BC008392.1 Homo sapiens uncoupling protein 3 (mitochondrial, proton carrier), mRNA (cDNA clone MGC:14479 IMAGE:4291158), complete cds PA
AK291889.1 Homo sapiens cDNA FLJ78613 complete cds, highly similar to Homo sapiens uncoupling protein 3 (mitochondrial, proton carrier) (UCP3), transcript variant short, mRNA P
AK290630.1 Homo sapiens cDNA FLJ77071 complete cds, highly similar to Homo sapiens uncoupling protein 3 (mitochondrial, proton carrier) (UCP3), transcript variant short, mRNA P
AK309873.1 Homo sapiens cDNA, FLJ99914 P
AK092685.1 Homo sapiens cDNA FLJ35366 fis, clone SKMUS2001215, highly similar to MITOCHONDRIAL UNCOUPLING PROTEIN 3 P
U82818.1 Homo sapiens UCP3S mRNA, complete cds PA
U84763.1 Homo sapiens UCP3 mRNA, complete cds P
AF001787.1 Homo sapiens uncoupling protein 3 mRNA, complete cds P
AF011449.1 Homo sapiens uncoupling protein-3 (UCP3) mRNA, nuclear gene encoding mitochondrial protein, complete cds P

EST sequences (44)

AI214734.1 Clone IMAGE:1840233 testis 3' read
AI632296.1 Clone IMAGE:2241514 uncharacterized tissue 3' read A
AI670961.1 Clone IMAGE:2305443 uncharacterized tissue 3' read A
Z28895.1 Clone B6C05 muscle
Z25295.1 Clone B6C05 muscle
Z28919.1 Clone C1A09 muscle
AI968020.1 Clone IMAGE:2516729 uncharacterized tissue 3' read A
AW295096.1 Clone IMAGE:2730345 uncharacterized tissue 3' read A
AW439483.1 Clone IMAGE:2778929 uterus 3' read A
CD616918.1 uncharacterized tissue P
CD616919.1 uncharacterized tissue P
AW589767.1 Clone IMAGE:2946200 uncharacterized tissue 3' read A
AW589893.1 Clone IMAGE:2946692 uncharacterized tissue 3' read A
AW770912.1 Clone IMAGE:3009496 lung 3' read A
AW970807.1 uncharacterized tissue
BE061953.1 mammary gland
CV023110.1 mixed 5' read P
CV407165.1 mammary gland
BE844207.1 testis
DN998196.1 Clone TC111702 mammary gland 5' read
BF670349.1 Clone IMAGE:4291158 muscle 5' read
DA566940.1 Clone HEART2010077 heart 5' read P
DA876189.1 Clone PROST2014241 prostate 5' read P
DA876282.1 Clone PROST2014359 prostate 5' read
DA894002.1 Clone SKMUS2001215 muscle 5' read P
DB020112.1 Clone TESTI2000166 testis 5' read
DA824916.1 Clone PERIC2005858 heart 5' read P
DA897213.1 Clone SKMUS2005192 muscle 5' read P
BF507985.1 Clone IMAGE:3088884 uncharacterized tissue 3' read A
DA899881.1 Clone SKMUS2008541 muscle 5' read P
DA763595.1 Clone NTONG2003779 mouth 5' read P
DB330941.1 Clone SKMUS2001215 muscle 3' read A
DW414312.1 liver
BG236319.1 Clone IMAGE:4142152 blood 3' read A
AL596731.1 Clone DKFZp451B221 spinal cord 5' read P
BM715026.1 Clone UI-E-EJ0-aht-b-19-0-UI eye 5' read
BQ446444.1 Clone UI-H-EU1-azz-d-24-0-UI connective tissue 3' read A
BF921552.1 brain
C14769.1 Clone 087B08 vascular 5' read
AA192553.1 Clone IMAGE:628529 muscle 3' read A
AA192136.1 Clone IMAGE:628529 muscle 5' read
BU739937.1 Clone UI-E-EJ0-aht-b-19-0-UI eye 3' read A
AA552167.1 Clone IMAGE:938069 intestine 3' read A
AA779805.1 Clone IMAGE:1034583 embryonic tissue 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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