Rho guanine nucleotide exchange factor (GEF) 33 (ARHGEF33)

Restricted Expression:

fetus [show more like this]

EST Profile:

Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]

GEO Profiles:

Experimental gene expression data (Gene Expression Omnibus).

cDNA Sources:

mixed; brain; lung; testis; pancreas; ovary

NCBI

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UGID:142762 UniGene Hs.99841 Homo sapiens (human) ARHGEF33

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Rho guanine nucleotide exchange factor (GEF) 33 (ARHGEF33)

Human protein-coding gene ARHGEF33. Represented by 48 ESTs from 14 cDNA libraries. EST representation biased toward fetus. Corresponds to reference sequence NM_001145451.2. [UniGene 142762 - Hs.99841]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_001138923.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	ARHGEF33 gene product	H. sapiens	100.0	869
XP_525737.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: rho guanine nucleotide exchange factor 33	P. troglodytes	99.8	869
XP_003908584.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: rho guanine nucleotide exchange factor 33	P. anubis	99.5	871
NP_001138924.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	rho guanine nucleotide exchange factor 33	M. musculus	94.6	849
Other hits (2 of 13) [Show all]		Species	Id(%)	Len(aa)
XP_002799285.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: hypothetical protein LOC713710	M. mulatta	99.1	851
XP_540156.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: rho guanine nucleotide exchange factor 33	C. lupus familiaris	97.5	872

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	2
Map position:	2p22.1
UniSTS entry:	Chr 2	G43628
UniSTS entry:	Chr 2	G59825
UniSTS entry:	Chr 2	RH102201

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (3)

AK123375.1	Homo sapiens cDNA FLJ41381 fis, clone BRCAN2011316	PA
AK094554.1	Homo sapiens cDNA FLJ37235 fis, clone BRAMY2002525
NM_001145451.2	Homo sapiens Rho guanine nucleotide exchange factor (GEF) 33 (ARHGEF33), mRNA	PA

EST sequences (10 of 48) [Show all sequences]

AI002334.1	Clone IMAGE:1601507	lung	3' read	P
AA909992.1	Clone IMAGE:1523139	mixed	3' read
AI125676.1	Clone IMAGE:1736796	testis	3' read	P
BX116314.1	Clone IMAGp998C245514_;_IMAGE:2229071	pancreas		A
BX108565.1	Clone IMAGp998D134413_;_IMAGE:1736796	testis		P
AI223322.1	Clone IMAGE:1840607	mixed	3' read	A
AI623510.1	Clone IMAGE:2229071	pancreas	3' read	A
AI684434.1	Clone IMAGE:2302632	mixed	3' read	P
CD511897.1	Clone IMAGE:30406813	mixed	5' read
Z40670.1	Clone c-2cd11	brain	3' read	A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria