> Serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) (SPINK2)
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UGID:142281     UniGene Hs.98243     Homo sapiens (human)   SPINK2 Order cDNA clone, Links
Serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) (SPINK2)

Human protein-coding gene SPINK2. Represented by 124 ESTs from 26 cDNA libraries. EST representation biased toward fetus. Corresponds to 9 reference sequences (different isoforms). [UniGene 142281 - Hs.98243]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001258647.1 serine protease inhibitor Kazal-type 2 isoform 1 precursor H. sapiens 100.0 133
Other hits (SpeciesId(%)Len(aa)
XP_001136884.1 PREDICTED: uncharacterized protein LOC736082 isoform 2 P. troglodytes 97.8 133
XP_003898900.1 PREDICTED: uncharacterized protein LOC101007785 P. anubis 88.1 133

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: fetus [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; mixed; connective tissue; epididymis; blood; uncharacterized tissue; pancreas; prostate; bone marrow
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q12
UniSTS entry: Chr 4 D4S3141 [Map Viewer]
UniSTS entry: RH11111
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

X57655.1 H.sapiens RNA for acrosin-trypsin inhibitor (HUSI-II) P
CR542135.1 Homo sapiens full open reading frame cDNA clone RZPDo834H0125D for gene SPINK2, serine protease inhibitor, Kazal type, 2 (acrosin-trypsin inhibitor); complete cds, without stopcodon P
NM_021114.3 Homo sapiens serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) (SPINK2), transcript variant 2, mRNA PA
BC022514.1 Homo sapiens serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor), mRNA (cDNA clone MGC:26562 IMAGE:4812189), complete cds PA
AK312222.1 Homo sapiens cDNA, FLJ92511, Homo sapiens serine protease inhibitor, Kazal type, 2(acrosin-trypsin inhibitor) (SPINK2), mRNA PA
GU727622.1 Homo sapiens epididymis tissue protein Li 172 mRNA, complete cds P
NR_073419.1 Homo sapiens serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) (SPINK2), transcript variant 9, non-coding RNA A
NR_073417.1 Homo sapiens serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) (SPINK2), transcript variant 7, non-coding RNA A
NM_001271721.1 Homo sapiens serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) (SPINK2), transcript variant 5, mRNA PA
NM_001271720.1 Homo sapiens serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) (SPINK2), transcript variant 4, mRNA PA
NM_001271719.1 Homo sapiens serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) (SPINK2), transcript variant 3, mRNA PA
NR_073418.1 Homo sapiens serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) (SPINK2), transcript variant 8, non-coding RNA A
NM_001271722.1 Homo sapiens serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) (SPINK2), transcript variant 6, mRNA PA
NM_001271718.1 Homo sapiens serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) (SPINK2), transcript variant 1, mRNA PA

EST sequences (10 of 124) [Show all sequences]

AA973772.1 Clone IMAGE:1586504 uncharacterized tissue 3' read A
AI001827.1 Clone IMAGE:1638118 testis 3' read
AI126426.1 Clone IMAGE:1735582 testis 3' read P
AI138846.1 Clone IMAGE:1737988 testis 3' read A
BM422396.1 testis A
BM422425.1 testis A
BM422945.1 testis
BM422980.1 testis
AA905437.1 Clone IMAGE:1506202 mixed 3' read A
AI350434.1 Clone IMAGE:1947880 uncharacterized tissue 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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