> Gremlin 2, DAN family BMP antagonist (GREM2)
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UGID:142265     UniGene Hs.98206     Homo sapiens (human)   GREM2
Gremlin 2, DAN family BMP antagonist (GREM2)

Human protein-coding gene GREM2. Represented by 65 ESTs from 43 cDNA libraries. Corresponds to reference sequence NM_022469.3. [UniGene 142265 - Hs.98206]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001095526.1 PREDICTED: gremlin-2 M. mulatta 100.0 167
XP_003893758.1 PREDICTED: gremlin-2 P. anubis 100.0 167
XP_525111.2 PREDICTED: gremlin-2 P. troglodytes 100.0 167
NP_071914.3 GREM2 gene product H. sapiens 100.0 167
NP_035955.1 gremlin-2 precursor M. musculus 95.8 167
NP_001017704.1 grem2 gene product D. rerio 71.8 162
NP_001083746.1 gremlin-1 precursor X. laevis 62.8 172
Other hits (2 of 22) [Show all]SpeciesId(%)Len(aa)
XP_547488.1 PREDICTED: gremlin-2 C. lupus familiaris 98.2 167
XP_001492621.2 PREDICTED: gremlin-2-like E. caballus 98.2 167

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; embryonic tissue; bone; intestine; uncharacterized tissue; prostate; uterus; vascular; connective tissue; placenta; mixed; lung; heart; stomach; adrenal gland; ovary
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q43
UniSTS entry: Chr 1 SHGC-76594 [Map Viewer]
UniSTS entry: Chr 1 A004V04 [Map Viewer]
UniSTS entry: Chr 1 RH68323 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (3)

BC046632.1 Homo sapiens gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis), mRNA (cDNA clone MGC:44218 IMAGE:5288555), complete cds PA
AK024848.1 Homo sapiens cDNA: FLJ21195 fis, clone COL00185 PA
NM_022469.3 Homo sapiens gremlin 2, DAN family BMP antagonist (GREM2), mRNA PA

EST sequences (10 of 65) [Show all sequences]

R17151.1 Clone IMAGE:31902 brain 5' read
AI097232.1 Clone IMAGE:1707191 heart 3' read A
AI151500.1 Clone IMAGE:1715888 placenta 3' read A
BX117421.1 Clone IMAGp998F19152_;_IMAGE:31902 brain A
BX089942.1 Clone IMAGp998J085590_;_IMAGE:2258407 stomach
R25728.1 Clone IMAGE:36690 brain 5' read
AI200117.1 Clone IMAGE:1757327 placenta 3' read A
AI597757.1 Clone IMAGE:2258407 stomach 3' read
R43248.1 Clone IMAGE:31902 brain 3' read A
AI797592.1 Clone IMAGE:2348296 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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