Lin-54 homolog (C. elegans) (LIN54)

Restricted Expression:

infant [show more like this]

EST Profile:

Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]

GEO Profiles:

Experimental gene expression data (Gene Expression Omnibus).

cDNA Sources:

brain; lymph node; liver; pharynx; embryonic tissue; thyroid; testis; pancreas; uncharacterized tissue; placenta; kidney; stomach; mammary gland; bone marrow; prostate; vascular; trachea; thymus; intestine; skin; uterus; lung; blood; mixed

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Finding cDNAs

UGID:141871 UniGene Hs.96952 Homo sapiens (human) LIN54

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Lin-54 homolog (C. elegans) (LIN54)

Human protein-coding gene LIN54. Represented by 77 ESTs from 52 cDNA libraries. EST representation biased toward infant. Corresponds to 3 reference sequences (different isoforms). [UniGene 141871 - Hs.96952]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
XP_003898732.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: protein lin-54 homolog isoform 2	P. anubis	100.0	748
XP_517185.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: protein lin-54 homolog isoform 3	P. troglodytes	100.0	748
NP_919258.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	LIN54 gene product	H. sapiens	100.0	748
XP_001083154.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: protein lin-54 homolog, partial	M. mulatta	99.8	812
NP_766302.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Lin54 gene product	M. musculus	98.3	748
NP_001070035.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	lin54 gene product	D. rerio	73.5	770
NP_610879.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Myb-interacting protein 120, isoform A	D. melanogaster	67.2	171
NP_502545.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Protein LIN-54, isoform b	C. elegans	58.8	204
NP_197951.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Tesmin/TSO1-like CXC domain-containing protein	A. thaliana	54.2	166
Other hits (2 of 43) [Show all]		Species	Id(%)	Len(aa)
XP_003640147.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: protein lin-54 homolog isoform 2	C. lupus familiaris	99.5	748
XP_001494323.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: protein lin-54 homolog isoform 2	E. caballus	99.3	748

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	4
Map position:	4q21.22
UniSTS entry:	Chr 1	D11S3114

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

BX537919.1	Homo sapiens mRNA; cDNA DKFZp686L18142 (from clone DKFZp686L18142)	PA
BX640966.1	Homo sapiens mRNA; cDNA DKFZp686G04165 (from clone DKFZp686G04165)	PA
BX640657.1	Homo sapiens mRNA; cDNA DKFZp686I20167 (from clone DKFZp686I20167)	PA
NM_194282.2	Homo sapiens lin-54 homolog (C. elegans) (LIN54), transcript variant 1, mRNA	P
AB111889.1	Homo sapiens mRNA for KIAA2037 protein	P
BC109277.2	Homo sapiens lin-54 homolog (C. elegans), mRNA (cDNA clone IMAGE:40028369), complete cds	P
BC109278.2	Homo sapiens lin-54 homolog (C. elegans), mRNA (cDNA clone MGC:129905 IMAGE:40028371), complete cds	P
AK292769.1	Homo sapiens cDNA FLJ77239 complete cds	P
NM_001115008.1	Homo sapiens lin-54 homolog (C. elegans) (LIN54), transcript variant 3, mRNA	P
NM_001115007.1	Homo sapiens lin-54 homolog (C. elegans) (LIN54), transcript variant 2, mRNA	P
AK294256.1	Homo sapiens cDNA FLJ50070 partial cds, weakly similar to Tesmin	P
AK299787.1	Homo sapiens cDNA FLJ50096 complete cds, weakly similar to Tesmin	P

EST sequences (10 of 77) [Show all sequences]

AI002947.1	Clone IMAGE:1698791	kidney	3' read	A
BX108765.1	Clone IMAGp998E225405_;_IMAGE:2187261	stomach		A
BX091994.1	Clone IMAGp998G175382_;_IMAGE:2178472	uterus		A
AI208524.1	Clone IMAGE:1839320	testis	3' read	A
CB115015.1	Clone L10ChoCK0-4-B09	liver	5' read	A
AI499214.1	Clone IMAGE:2178472	uterus	3' read
AI758142.1	Clone IMAGE:2284351	kidney	3' read	A
AI802568.1	Clone IMAGE:2187261	stomach	3' read	A
CD514631.1	Clone IMAGE:30408522	brain	5' read
AW016457.1	Clone IMAGE:2710827	uncharacterized tissue	3' read	A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria