> Apolipoprotein A-I (APOA1)
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UGID:141543     UniGene Hs.93194     Homo sapiens (human)   APOA1 Order cDNA clone, Links
Apolipoprotein A-I (APOA1)

Human protein-coding gene APOA1. Represented by 726 ESTs from 77 cDNA libraries. EST representation biased toward liver tumor. Corresponds to reference sequence NM_000039.1. [UniGene 141543 - Hs.93194]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001153383.1 PREDICTED: apolipoprotein A-I isoform 2 P. troglodytes 100.0 266
NP_000030.1 APOA1 gene product H. sapiens 100.0 266
NP_033822.2 Apoa1 gene product M. musculus 72.7 263
NP_001079732.1 apolipoprotein A-I precursor X. laevis 45.0 202
Other hits (2 of 13) [Show all]SpeciesId(%)Len(aa)
XP_001090535.1 PREDICTED: apolipoprotein A-I isoform 1 M. mulatta 97.0 266
NP_001106116.1 APOA1 gene product P. anubis 97.0 266

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: liver tumor [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: liver; mixed; testis; spleen; lung; uncharacterized tissue; brain; embryonic tissue; heart; ovary; placenta; pancreas; blood; intestine; thymus; muscle
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q23-q24
UniSTS entry: Chr 11 RH11465
UniSTS entry: Chr 11 RH1581
UniSTS entry: Chr 11 REN72947
UniSTS entry: Chr 11 REN72948
UniSTS entry: Chr 11 G44357
UniSTS entry: Chr 11 GDB:182584
UniSTS entry: Chr 11 REN72940
UniSTS entry: Chr 11 stSG601816
UniSTS entry: Chr 18 D18S1032 [Map Viewer]
UniSTS entry: Chr 18 GDB:177915
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

NM_000039.1 Homo sapiens apolipoprotein A-I (APOA1), mRNA P
M29068.1 Human apolipoprotein A-I mRNA, 3' end P
BC110286.1 Homo sapiens apolipoprotein A-I, mRNA (cDNA clone MGC:117399 IMAGE:5164525), complete cds PA
BC005380.1 Homo sapiens apolipoprotein A-I, mRNA (cDNA clone MGC:12499 IMAGE:3934992), complete cds PA
M27875.1 Human apolipoprotein A-I mRNA, complete cds P
X00566.1 Human mRNA for lipoprotein apoAI P
AK292231.1 Homo sapiens cDNA FLJ75790 complete cds, highly similar to Homo sapiens apolipoprotein A-I (APOA1), mRNA PA
X02162.1 Human mRNA for apolipoprotein AI (apo AI)= PA
M11791.1 Human preproapo-A-I mRNA, complete cds P

EST sequences (10 of 726) [Show all sequences]

AA954987.1 Clone IMAGE:1577794 mixed 3' read A
AA968770.1 Clone IMAGE:1597460 uncharacterized tissue 3' read P
AA969019.1 Clone IMAGE:1579580 mixed 3' read A
AA975501.1 Clone IMAGE:1561203 mixed 3' read PA
AA993248.1 Clone IMAGE:1621170 testis 3' read PA
AA994272.1 Clone IMAGE:1625418 mixed 3' read A
AA888198.1 Clone IMAGE:1436837 liver 3' read A
AI004301.1 Clone IMAGE:1626023 mixed 3' read P
AI005645.1 Clone IMAGE:1641610 testis 3' read A
AI015476.1 Clone IMAGE:1618640 testis 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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